Results 11 to 20 of about 64,835 (235)

Prevalence, risk factors and treatment outcomes of fluoroquinolones-associated tendinopathy in tuberculosis patients at university hospital, Thailand

open access: yesHeliyon, 2023
Background: Tuberculosis (TB) is an epidemic disease in Thailand. Fluoroquinolones are used to treat TB and have a lengthy treatment course. Therefore, many patients may have adverse effects from these medications.
Jirarat Chongboonwatana   +2 more
doaj   +1 more source

Association Between Aortic Aneurysm and Aortic Dissection With Fluoroquinolones Use in Patients With Urinary Tract Infections: A Population‐Based Cohort Study

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Fluoroquinolones are first‐line antibiotics recommended for the treatment of complicated urinary tract infections (UTIs), with frequent reports of adverse effects of aortic aneurysm (AA) and aortic dissection (AD).
Yin‐Yang Chen   +6 more
doaj   +1 more source

Fluoroquinolones’ Biological Activities against Laboratory Microbes and Cancer Cell Lines

open access: yesMolecules, 2022
Development of novel derivatives to rein in and fight bacteria have never been more demanding, as microbial resistance strains are alarmingly increasing.
Ghadeer A. R. Y. Suaifan   +2 more
doaj   +1 more source

Fluoroquinolone Antimicrobial Agents [PDF]

open access: yesNew England Journal of Medicine, 1989
The fluoroquinolones, a new class of potent orally absorbed antimicrobial agents, are reviewed, considering structure, mechanisms of action and resistance, spectrum, variables affecting activity in vitro, pharmacokinetic properties, clinical efficacy, emergence of resistance, and tolerability. The primary bacterial target is the enzyme deoxyribonucleic
D C, Hooper, J S, Wolfson
openaire   +3 more sources

Transporter and metabolizer gene polymorphisms affect fluoroquinolone pharmacokinetic parameters

open access: yesFrontiers in Pharmacology, 2022
Tuberculosis (TB) is an infectious disease that occurs globally. Treatment of TB has been hindered by problems with multidrug-resistant strains (MDR-TB). Fluoroquinolones are one of the main drugs used for the treatment of MDR-TB.
Nurul Annisa   +5 more
doaj   +1 more source

The Resistance Mechanism of Mycoplasma bovis From Yaks in Tibet to Fluoroquinolones and Aminoglycosides

open access: yesFrontiers in Veterinary Science, 2022
Mycoplasma bovis (M. bovis) is one of the important pathogens for yaks. Aminoglycosides and fluoroquinolones are frequently used medications for the treatment of M. bovis. Drug-resistant strains were inevitable with the abuse of antibiotics.
Jiaqiang Niu   +5 more
doaj   +1 more source

The incidence of collagen-associated adverse events in pediatric population with the use of fluoroquinolones: a nationwide cohort study in Taiwan

open access: yesBMC Pediatrics, 2020
Background To evaluate the safety of using fluoroquinolones in pediatric population in Taiwan. Methods Patients aged 0~18 years old with fluoroquinolones prescriptions ≥5 consecutive days during year 2000 to 2013 were selected from the National Health ...
Pei-Han Yu   +6 more
doaj   +1 more source

Systemic use of fluoroquinolone in children [PDF]

open access: yesKorean Journal of Pediatrics, 2013
Fluoroquinolones are an important class of antibiotics that are widely used in adult patients because of their broad spectrum of activity, good tissue penetration, and oral bioavailability.
Soo-Han Choi   +2 more
doaj   +1 more source

A Review of the Resistance Mechanisms for β-Lactams, Macrolides and Fluoroquinolones among Streptococcus pneumoniae

open access: yesMedicina, 2023
Streptococcus pneumoniae (S. pneumoniae) is a bacterial species often associated with the occurrence of community-acquired pneumonia (CAP). CAP refers to a specific kind of pneumonia that occurs in individuals who acquire the infection outside of a ...
Nurul Izzaty Najwa Zahari   +14 more
doaj   +1 more source

Concentrations of Ciprofloxacin in the World’s Rivers Are Associated with the Prevalence of Fluoroquinolone Resistance in Escherichia coli: A Global Ecological Analysis

open access: yesAntibiotics, 2022
Background: Extremely low concentrations of ciprofloxacin may select for antimicrobial resistance. A recent global survey found that ciprofloxacin concentrations exceeded safe levels at 64 sites. In this study, I assessed if national median ciprofloxacin
Chris Kenyon
doaj   +1 more source

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