Results 211 to 220 of about 95,509 (260)
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Infectious Disease Clinics of North America, 2000
The fluoroquinolone class of antimicrobial agents has expanded dramatically in the last 5 years and will continue to grow over the next decade. This article discusses the newer fluoroquinolones in detail, including pharmacokinetics, pharmacodynamics, safety, and drug interactions, and the spectrum of in vitro activity.
J A, O'Donnell, S P, Gelone
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The fluoroquinolone class of antimicrobial agents has expanded dramatically in the last 5 years and will continue to grow over the next decade. This article discusses the newer fluoroquinolones in detail, including pharmacokinetics, pharmacodynamics, safety, and drug interactions, and the spectrum of in vitro activity.
J A, O'Donnell, S P, Gelone
+5 more sources
Mayo Clinic Proceedings, 1991
The fluoroquinolone class of antibiotics promises to become as diverse and as important as beta-lactam agents. The fluoroquinolones inhibit bacterial DNA gyrase and are bactericidal. All fluoroquinolones have potent activity against most gram-negative bacteria; ciprofloxacin is the most active against Pseudomonas aeruginosa.
R C, Walker, A J, Wright
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The fluoroquinolone class of antibiotics promises to become as diverse and as important as beta-lactam agents. The fluoroquinolones inhibit bacterial DNA gyrase and are bactericidal. All fluoroquinolones have potent activity against most gram-negative bacteria; ciprofloxacin is the most active against Pseudomonas aeruginosa.
R C, Walker, A J, Wright
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Infectious Disease Clinics of North America, 1995
Since the introduction of the floroquinolones for clinical use in the late 1980s, they have been used successfully for a large number of clinical situations. As experience accumulates, the indications and optimal use of these agents gradually become more clear.
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Since the introduction of the floroquinolones for clinical use in the late 1980s, they have been used successfully for a large number of clinical situations. As experience accumulates, the indications and optimal use of these agents gradually become more clear.
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Mayo Clinic Proceedings, 1999
The quinolones are broad-spectrum antibacterial agents that have a novel mechanism of action. As synthetic compounds, these agents have been developed extensively to optimize antimicrobial activity, pharmacokinetic properties, and drug safety. Although earlier quinolones were effective only in the genitourinary and gastrointestinal tracts and only had ...
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The quinolones are broad-spectrum antibacterial agents that have a novel mechanism of action. As synthetic compounds, these agents have been developed extensively to optimize antimicrobial activity, pharmacokinetic properties, and drug safety. Although earlier quinolones were effective only in the genitourinary and gastrointestinal tracts and only had ...
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Postgraduate Medicine, 1991
Fluoroquinolones are the newest antibiotics for treatment of some infections caused by highly resistant bacteria (eg, Pseudomonas aeruginosa). Clinically sound indications for these drugs include resistant infections of the urinary, intestinal, and respiratory tracts; otitis externa; osteomyelitis; foot infections in diabetic patients; and late ...
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Fluoroquinolones are the newest antibiotics for treatment of some infections caused by highly resistant bacteria (eg, Pseudomonas aeruginosa). Clinically sound indications for these drugs include resistant infections of the urinary, intestinal, and respiratory tracts; otitis externa; osteomyelitis; foot infections in diabetic patients; and late ...
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Ophthalmology, 2009
To report a possible association between fluoroquinolones and diplopia.Database study.A total of 171 subjects were studied.Spontaneous reports from the National Registry of Drug-Induced Ocular Side Effects, World Health Organization, and Food and Drug Administration were collected on fluoroquinolones and diplopia.Data garnered from the spontaneous ...
Frederick W, Fraunfelder +1 more
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To report a possible association between fluoroquinolones and diplopia.Database study.A total of 171 subjects were studied.Spontaneous reports from the National Registry of Drug-Induced Ocular Side Effects, World Health Organization, and Food and Drug Administration were collected on fluoroquinolones and diplopia.Data garnered from the spontaneous ...
Frederick W, Fraunfelder +1 more
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Journal of the American Academy of Orthopaedic Surgeons, 2002
Alan M, Levine, John R, DiBona
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Alan M, Levine, John R, DiBona
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1998
Abstract Quinolones have been used therapeutically for more than 30 years, predominantly for treatment of urinary tract infections. As the antimicrobial and pharrnacokinetic characteristics of the older quinolones, such as nalidixic acid or oxolinic acid, were far from optimal, they have been considered second-line therapeutics.
Ralf Stahlmann, Hartmut Lode
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Abstract Quinolones have been used therapeutically for more than 30 years, predominantly for treatment of urinary tract infections. As the antimicrobial and pharrnacokinetic characteristics of the older quinolones, such as nalidixic acid or oxolinic acid, were far from optimal, they have been considered second-line therapeutics.
Ralf Stahlmann, Hartmut Lode
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