Results 21 to 30 of about 14,712 (219)

Quinolone Complexes with Lanthanide Ions: An Insight into their Analytical Applications and Biological Activity

open access: yesMolecules, 2020
Quinolones comprise a series of synthetic bactericidal agents with a broad spectrum of activity and good bioavailability. An important feature of these molecules is their capacity to bind metal ions in complexes with relevant biological and analytical ...
Ana-Mădălina Măciucă   +2 more
doaj   +1 more source

Adherence to Hospital Antibiotic Policy for Treatment of Escherichia coli ESBL in Urine [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: Escherichia coli are the most common uropathogen worldwide accounting for 80% of the Urinary Tract Infections (UTIs). Nosocomial infections caused by Multi-drug resistant Gram negative bacteria expressing Extended Spectrum β Lactamase ...
R. Someshwaran   +3 more
doaj   +1 more source

Risk Factors and Treatment Outcome Analysis Associated with Second-Line Drug-Resistant Tuberculosis

open access: yesJournal of Respiration, 2021
The present study aimed at analyzing the treatment outcomes and risk factors associated with fluoroquinolone drug resistance having mutations in the gyrA and gyrB genes.
Muralidhar Aaina   +5 more
doaj   +1 more source

Revisiting Oral Fluoroquinolone and Multivalent Cation Drug-Drug Interactions: Are They Still Relevant?

open access: yesAntibiotics, 2019
Fluoroquinolones are a widely-prescribed, broad-spectrum class of antibiotics with several oral formulations notable for their high bioavailability. For certain infections, fluoroquinolones are the first line or only treatment choice.
Stuart K. Pitman   +5 more
doaj   +1 more source

Lomefloxacin—Occurrence in the German River Erft, Its Photo-Induced Elimination, and Assessment of Ecotoxicity

open access: yesClean Technologies, 2020
Pharmaceuticals in waters represent a worldwide problem of today. Advanced oxidation processes (AOPs) are being researched for elimination of the ecological hazard.
Melanie Voigt   +6 more
doaj   +1 more source

Fluoroquinolones and Biofilm: A Narrative Review

open access: yesPharmaceuticals
Background: Biofilm-associated infections frequently span multiple body sites and represent a significant clinical challenge, often requiring a multidisciplinary approach involving surgery and antimicrobial therapy.
Nicholas Geremia   +12 more
doaj   +1 more source

Pharmacokinetics and pharmacodynamics of fluoroquinolones [PDF]

open access: yesClinical Microbiology and Infection, 1998
'Division of Clinical Pharmacology, Department of Medicine, Albany Medical College, Albany, New York, USA; 21NSERM U479, Service d'Hematologie et d'Immunologie Biologiques, CHU Xavier BICHAT, Paris, France; 3Department of Infectious Diseases, Uppsala University Hospital, Uppsala, Sweden; 4Hoechst Marion Roussel Inc, Bridgewater, New Jersey, USA; 5Med ...
Marie-Thérèse Labro   +6 more
openaire   +3 more sources

The insulinotropic effect of fluoroquinolones [PDF]

open access: yesBiochemical Pharmacology, 2009
Antimicrobial fluoroquinolones induce, with strongly varying frequency, life-threatening hypoglycemias, which is explained by their ability to block K(ATP) channels in pancreatic B-cells and thus to initiate insulin secretion. In apparent contradiction to this, we observed that none of the fluoroquinolones in this study (gatifloxacin, moxifloxacin ...
Ingo Rustenbeck   +6 more
openaire   +3 more sources

Impact of Fluoroquinolones on Tendon Health: A Comprehensive Overview for the General Population and Athletes

open access: yesQuality in Sport
Introduction: Fluoroquinolones are a class of broad-spectrum antibiotics widely used to treat various bacterial infections. Despite their effectiveness, increasing evidence links fluoroquinolones to tendinopathy and tendon rupture, with cases occurring ...
Emilia Kucharczyk   +2 more
doaj   +1 more source

Cardiac toxicity of fluoroquinolones and bedaquiline

open access: yesТуберкулез и болезни лёгких, 2019
The review analyzes data on the impact of fluoroquinolones and bedaquiline on the cardiac conduction system. The dependence of the cardiotoxic effect of fluoroquinolones on their influence on the potassium channels of cardiomyocytes is presented.
G. N. Mozhokinа, A. G. Sаmoylovа
doaj   +1 more source

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