Results 21 to 30 of about 14,712 (219)
Quinolones comprise a series of synthetic bactericidal agents with a broad spectrum of activity and good bioavailability. An important feature of these molecules is their capacity to bind metal ions in complexes with relevant biological and analytical ...
Ana-Mădălina Măciucă+2 more
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Adherence to Hospital Antibiotic Policy for Treatment of Escherichia coli ESBL in Urine [PDF]
Introduction: Escherichia coli are the most common uropathogen worldwide accounting for 80% of the Urinary Tract Infections (UTIs). Nosocomial infections caused by Multi-drug resistant Gram negative bacteria expressing Extended Spectrum β Lactamase ...
R. Someshwaran+3 more
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Risk Factors and Treatment Outcome Analysis Associated with Second-Line Drug-Resistant Tuberculosis
The present study aimed at analyzing the treatment outcomes and risk factors associated with fluoroquinolone drug resistance having mutations in the gyrA and gyrB genes.
Muralidhar Aaina+5 more
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Fluoroquinolones are a widely-prescribed, broad-spectrum class of antibiotics with several oral formulations notable for their high bioavailability. For certain infections, fluoroquinolones are the first line or only treatment choice.
Stuart K. Pitman+5 more
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Pharmaceuticals in waters represent a worldwide problem of today. Advanced oxidation processes (AOPs) are being researched for elimination of the ecological hazard.
Melanie Voigt+6 more
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Fluoroquinolones and Biofilm: A Narrative Review
Background: Biofilm-associated infections frequently span multiple body sites and represent a significant clinical challenge, often requiring a multidisciplinary approach involving surgery and antimicrobial therapy.
Nicholas Geremia+12 more
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Pharmacokinetics and pharmacodynamics of fluoroquinolones [PDF]
'Division of Clinical Pharmacology, Department of Medicine, Albany Medical College, Albany, New York, USA; 21NSERM U479, Service d'Hematologie et d'Immunologie Biologiques, CHU Xavier BICHAT, Paris, France; 3Department of Infectious Diseases, Uppsala University Hospital, Uppsala, Sweden; 4Hoechst Marion Roussel Inc, Bridgewater, New Jersey, USA; 5Med ...
Marie-Thérèse Labro+6 more
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The insulinotropic effect of fluoroquinolones [PDF]
Antimicrobial fluoroquinolones induce, with strongly varying frequency, life-threatening hypoglycemias, which is explained by their ability to block K(ATP) channels in pancreatic B-cells and thus to initiate insulin secretion. In apparent contradiction to this, we observed that none of the fluoroquinolones in this study (gatifloxacin, moxifloxacin ...
Ingo Rustenbeck+6 more
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Introduction: Fluoroquinolones are a class of broad-spectrum antibiotics widely used to treat various bacterial infections. Despite their effectiveness, increasing evidence links fluoroquinolones to tendinopathy and tendon rupture, with cases occurring ...
Emilia Kucharczyk+2 more
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Cardiac toxicity of fluoroquinolones and bedaquiline
The review analyzes data on the impact of fluoroquinolones and bedaquiline on the cardiac conduction system. The dependence of the cardiotoxic effect of fluoroquinolones on their influence on the potassium channels of cardiomyocytes is presented.
G. N. Mozhokinа, A. G. Sаmoylovа
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