Results 31 to 40 of about 64,835 (235)

Impact of Fluoroquinolones on Tendon Health: A Comprehensive Overview for the General Population and Athletes

Quality in Sport
Introduction: Fluoroquinolones are a class of broad-spectrum antibiotics widely used to treat various bacterial infections. Despite their effectiveness, increasing evidence links fluoroquinolones to tendinopathy and tendon rupture, with cases occurring ...
Emilia Kucharczyk, Natalia Kucharczyk, Karolina Pawłuszkiewicz   +2 more
doaj   +1 more source

A Rare Instance of Levofloxacin Induced Myoclonus [PDF]

Journal of Clinical and Diagnostic Research, 2017
Levofloxacin is a widely used fluoroquinolone, mainly as a respiratory antimicrobial agent. It is employed as a second line therapeutic modality in pulmonary tuberculosis as well.
Sushil Kiran Kunder, A. Avinash, Veena Nayak, Amod Tilak   +3 more
doaj   +1 more source

Fluoroquinolones and Biofilm: A Narrative Review

Pharmaceuticals
Background: Biofilm-associated infections frequently span multiple body sites and represent a significant clinical challenge, often requiring a multidisciplinary approach involving surgery and antimicrobial therapy.
Nicholas Geremia, Federico Giovagnorio, Agnese Colpani, Andrea De Vito, Alexandru Botan, Giacomo Stroffolini, Dan-Alexandru Toc, Verena Zerbato, Luigi Principe, Giordano Madeddu, Roberto Luzzati, Saverio Giuseppe Parisi, Stefano Di Bella   +12 more
doaj   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Recurrent cystitis in women: principles of rational therapy

Медицинский совет, 2022
Introduction. Urinary tract infections (UTIs) are one of the most common disease among women.Aim. To determine the efficacy and tolerability of furazidin in the treatment of patients with exacerbation of chronic recurrent cystitis.Material and methods. a 
E. V. Kulchavenya, S. Yu. Shevchenko, D. P. Kholtobin   +2 more
doaj   +1 more source

An Engineered Solidified Peptide Hemocyte Sponge as Nanomotor Storage to Combat Bacterial Colitis

Advanced Science, EarlyView.
Peptides immobilized via nickel coordination can stabilize the framework structure. Following coating with red blood cell membranes, these constructs are capable of continuously sequestering endotoxins and mitigating colonic pathogenic damage by alleviating bacterial‐induced ferroptosis.
Yuxin Fang, Jianming Yan, Tongxin Yu, Zichuan An, Kaikai Lv, Chenyu Xue, Hongyang Yu, Na Dong, Anshan Shan   +8 more
wiley   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

7-(1-Methyl-3-Pyrrolyl-)-4,6-Dinitrobenzofuroxan Reduces the Frequency of Antibiotic Resistance Mutations Induced by Ciprofloxacin in Bacteria [PDF]

International Journal of Biomedicine, 2016
The aim of the present study was to investigate biological properties of the novel nitrobenzoxadiazole derivative 7-(1-methyl-3-pyrrolyl-)-4,6-dinitrobenzofuroxan.
Vladimir A. Chistyakov, Evgeniya V. Prazdnova, Evgeniya Y. Kharchenko, Sergey V. Kurbatov, Mikhail M. Batiushin, Ekaterina S. Levitskaya, Maria S. Mazanko, Mikhail N. Churilov   +7 more
doaj   +1 more source

Assessment of Knowledge Regarding Safety Profile, Use, and Boxed Warnings of Fluoroquinolones Among Healthcare Professionals in Saudi Arabia: A Potential Implication for Drug Regulatory Authorities

Frontiers in Medicine, 2022
BackgroundDespite a series of “boxed warnings” (BWs) issued by the US Food and Drug Administration (FDA), fluoroquinolones (FQs) are among the most prescribed antibiotics across the world.
Tauqeer Hussain Mallhi, Abdullah Salah Alanazi, Abdullah Salah Alanazi, Yusra Habib Khan, Nasser Hadal Alotaibi, Muhammad Salman, Abdulaziz Ibrahim Alzarea, Salah-Ud-Din Khan, Nabil K. Alruwaili, Alaa Salah Alenazi, Ahmed D. Alatawi, Zafar Iqbal, Muhammad Hammad Butt, Muhammad Shahid Iqbal   +13 more
doaj   +1 more source

Cardiotoxicity of fluoroquinolones [PDF]

Journal of Antimicrobial Chemotherapy, 2002
Currently marketed fluoroquinolones enjoy an admirable safety profile that is not matched by any other antibiotic group. The widespread use of fluoroquinolones in the elderly, who are susceptible to cardiac arrhythmias because of underlying heart diseases, metabolic derangement and use of anti-arrhythmic agents and other medications that prolong the QT
Ethan, Rubinstein, John, Camm
openaire   +2 more sources