Results 51 to 60 of about 132,194 (344)

Pharmacokinetics and pharmacodynamics of fluoroquinolones [PDF]

Clinical Microbiology and Infection, 1998
'Division of Clinical Pharmacology, Department of Medicine, Albany Medical College, Albany, New York, USA; 21NSERM U479, Service d'Hematologie et d'Immunologie Biologiques, CHU Xavier BICHAT, Paris, France; 3Department of Infectious Diseases, Uppsala University Hospital, Uppsala, Sweden; 4Hoechst Marion Roussel Inc, Bridgewater, New Jersey, USA; 5Med ...
Marie-Thérèse Labro, Willi Weber, Fritz Sörgel, George L. Drusano, Paul Mendes, Otto Cars, Pramod M. Shah   +6 more
openaire   +3 more sources

Evaluation of the efficacy and safety of high dose short duration enrofloxacin treatment regimen for uncomplicated urinary tract infections in dogs. [PDF]

, 2012
BackgroundUncomplicated urinary tract infections (UTI) in dogs usually are treated with antimicrobial drugs for 10-14 days. Shorter duration antimicrobial regimens have been evaluated in human patients.HypothesisA high dose short duration (HDSD ...
Chew, DJ, Daniels, JB, Irom, S, Keil, D, Settje, T, Smith, A, Sykes, JE, Wang, Y, Westropp, JL   +8 more
core   +1 more source

Fluoroquinolones and Biofilm: A Narrative Review

Pharmaceuticals
Background: Biofilm-associated infections frequently span multiple body sites and represent a significant clinical challenge, often requiring a multidisciplinary approach involving surgery and antimicrobial therapy.
Nicholas Geremia, Federico Giovagnorio, Agnese Colpani, Andrea De Vito, Alexandru Botan, Giacomo Stroffolini, Dan-Alexandru Toc, Verena Zerbato, Luigi Principe, Giordano Madeddu, Roberto Luzzati, Saverio Giuseppe Parisi, Stefano Di Bella   +12 more
doaj   +1 more source

The insulinotropic effect of fluoroquinolones [PDF]

Biochemical Pharmacology, 2009
Antimicrobial fluoroquinolones induce, with strongly varying frequency, life-threatening hypoglycemias, which is explained by their ability to block K(ATP) channels in pancreatic B-cells and thus to initiate insulin secretion. In apparent contradiction to this, we observed that none of the fluoroquinolones in this study (gatifloxacin, moxifloxacin ...
Ingo Rustenbeck, Anja Pflöger, Christine Kriete, H Ghaly, Seher Sahin, Ulrike Holzgrabe, Bernd J. Zünkler   +6 more
openaire   +3 more sources

Potency of marbofloxacin for pig pneumonia pathogens Actinobacillus pleuropneumoniae and Pasteurella multocida: Comparison of growth media [PDF]

, 2017
Pharmacodynamic properties of marbofloxacin were established for six isolates each of the pig respiratory tract pathogens, Actinobacillus pleuropneumoniae and Pasteurella multocida.
Dorey, L, Hobson, S, Lees, P
core   +1 more source

Fluoroquinolones and collagen associated severe adverse events: a longitudinal cohort study

BMJ Open, 2015
Objectives Fluoroquinolone-associated tendon ruptures are a recognised complication, but other severe collagen-associated adverse events may also be possible.
N. Daneman, Hong Lu, D. Redelmeier
semanticscholar   +1 more source

Results of A Local Combination Therapy Antibiogram For \u3cem\u3ePseudomonas Aeruginosa\u3c/em\u3e Isolates: Is Double Worth The Trouble? [PDF]

, 2017
Purpose: To determine the frequency at which fluoroquinolones and aminoglycosides demonstrate in vitro activity against non-urinary, non-skin/skin structure Pseudomonas aeruginosa isolates exhibiting decreased susceptibilities to one or more β-lactam ...
Davis, Jim, Dilworth, Thomas J., Elshaboury, Ramy, Munson, Erik, Song, Matthew   +4 more
core   +1 more source

A Photothermal‐Photocatalytic Textile With Efficient Thermal Management for Boosting Ciprofloxacin Purification

Aggregate, EarlyView.
A photothermal‐photocatalytic textile with carbon fiber felts decorated with TiO₂ films is proposed to purify ciprofloxacin (CIP) in water. It shows high solar absorption and efficient water evaporation. The local thermal effect can effectively enhance the catalytic degradation.
Yuge Wang, Lipei Ren, Yan Zhuang, Dongfang Liu, Zhixun Zhang, Lei Zhuo, Qian Zhang, Xiwei Guo, Xingfang Xiao, He Zhu   +9 more
wiley   +1 more source

Cardiac toxicity of fluoroquinolones and bedaquiline

Туберкулез и болезни лёгких, 2019
The review analyzes data on the impact of fluoroquinolones and bedaquiline on the cardiac conduction system. The dependence of the cardiotoxic effect of fluoroquinolones on their influence on the potassium channels of cardiomyocytes is presented.
G. N. Mozhokinа, A. G. Sаmoylovа
doaj   +1 more source

Patients at Risk for Aortic Rupture Often Exposed to Fluoroquinolones during Hospitalization

Antimicrobial Agents and Chemotherapy, 2018
Several studies have indicated that fluoroquinolone use may be associated with an increased risk of aortic aneurysm or dissection (AAD). Because patients with AAD or Marfan syndrome are at increased risk for aortic rupture, we performed a retrospective ...
W. C. Frankel, B. Trautner, Andrew Spiegelman, L. Grigoryan, S. Lemaire   +4 more
semanticscholar   +1 more source