Results 101 to 110 of about 290,304 (371)

Experimental Study Evaluating the Effect of Combined Methotrexate and Fluorouracil Therapy on Anemia in Mice With L1210 Lymphoid Leukemia

open access: yesPteridines, 1997
Combined methotrexate (MTX) and fluorouracil (FU) has heen used for many years to treat neoplastic diseases. However, clinical and laboratory snldies are still carried out to explain the changes that the therapeutic and toxic effects undergo when MTX and
Graczyk Julita
doaj   +1 more source

Minimal hepatic toxicity of Onyx-015: spatial restriction of coxsackie-adenoviral receptor in normal liver. [PDF]

open access: yes, 2007
We administered an adenoviral vector, Onyx-015, into the hepatic artery of patients with metastatic colorectal cancer involving the liver. Thirty-five patients enrolled in this multi-institutional phase I/II trial received up to eight arterial infusions ...
Au, T   +5 more
core  

Durable response using regorafenib in an elderly patient with metastatic colorectal cancer: case report. [PDF]

open access: yes, 2015
Regorafenib, an oral multikinase inhibitor, was approved in September 2012 by the US Food and Drug Administration for the treatment of patients with metastatic colorectal cancer.
Herman, June   +3 more
core   +3 more sources

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

open access: yesAdvanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Treatment of porokeratosis of Mibelli with combined use of topical fluorouracil and calcipotriene

open access: yesJAAD Case Reports, 2021
Jennifer E. Yeh, MD, PhD   +2 more
doaj   +1 more source

Effect of Fluorouracil Combined With Harmine on Induction of Apoptosis in Apoptosis Induction in Pancreatic Cancer Cells (AsPC-1) and the Expression of Apoptotic Genes (BAX, P53, Caspase-3, and Caspase-9)

open access: yesComplementary Medicine Journal of Faculty of Nursing and Midwifery, 2022
Objective: Pancreatic cancer is one of the deadliest cancers related to the digestive system in the world. Due to the increasing resistance of cancer cells to chemotherapy and its side effects, there is a need for drugs with fewer side effects and ...
Fereshte Sirjani   +2 more
doaj  

Effects of Mitomycin C in Early Conjunctival Inflammation after Pterygium Surgery [PDF]

open access: yes, 2016
Purpose: The purpose of this study was to compare inflammatory events and graft characteristics 1 month and 6 months after conjunctival limbal autograft (CLAU) with and without intraoperative mitomycin C (MMC).
Asaad Ammaar, Mouafk   +4 more
core   +2 more sources

DPYD and Fluorouracil-Based Chemotherapy: Mini Review and Case Report

open access: yesPharmaceutics, 2019
5-Fluorouracil remains a foundational component of chemotherapy for solid tumour malignancies. While considered a generally safe and effective chemotherapeutic, 5-fluorouracil has demonstrated severe adverse event rates of up to 30%.
Theodore J Wigle   +3 more
semanticscholar   +1 more source

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

open access: yesAdvanced Science, EarlyView.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu   +8 more
wiley   +1 more source

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