Results 91 to 100 of about 105,478 (251)

Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa, Birhanetensay Masresha Altaye, Yuh‐Pyng Sher   +2 more
wiley   +1 more source

Study of the antimutagenic effects of plant polyphenols under the action of genotoxicants

Journal of Education, Health and Sport, 2019
In the test of dominant lethal germ cell mutations in male rats, the effect of phenobarbital and fluorouracil genotoxicants and their combined administration with the biotrit-C preparation, obtained from wheat seedlings and containing plant polyphenols ...
V. S. Ivanov
doaj  

Development and validation of a nutrition risk screening for patients with childhood cancer in Brazil (NUTRICCAN)

Nutrition in Clinical Practice, EarlyView.
Abstract Background Diagnosing malnutrition in patients with pediatric cancer is challenging because tumor masses can interfere with anthropometric measurements. STRONGkids considers cancer a general risk factor, whereas Screening Tool for Childhood Cancer (SCAN) classifies patients as at risk or not, potentially missing those who need nutrition ...
Cristiane Ferreira Marçon, Carolina Araújo dos Santos, Fernanda Luisa Ceragioli Oliveira   +2 more
wiley   +1 more source

Quantum Chemical Properties of Fluorouracil/XZn11O12 (X = Zn, Cu, Fe, Ni) Nanocomplexes and Interactions with Human Serum Albumin

ChemistryOpen
This research focused on structural, electronic, and interaction properties of fluorouracil (5‐FU) adsorbed on transition metal (TM)‐doped ZnO nanoclusters (XZn11O12, where X = Zn, Cu, Fe, Ni) using density functional theory (DFT) at the B3LYP/LANL2DZ ...
Mohan Bahadur Kshetri, Navin Sharma, Kamal Khanal, Madhav Prasad Ghimire, Tika Ram Lamichhane   +4 more
doaj   +1 more source

Addressing the distressing: Pancreatic enzyme replacement therapy mitigates abdominal symptoms and weight loss during chemotherapy for advanced pancreatic cancer: A prospective study

Nutrition in Clinical Practice, EarlyView.
Abstract Background Pancreatic enzyme insufficiency (PEI) contributes to symptom burden and malnutrition in advanced pancreatic cancer (aPC). We aimed to evaluate the impact of pancreatic enzyme replacement therapy (PERT) on symptom burden and weight during chemotherapy.
Pamela N. Klassen, Christina A. Kim, Jessica Kasnik, Michael B. Sawyer, Sunita Ghosh, Vickie Baracos, Vera C. Mazurak   +6 more
wiley   +1 more source

Efficacy and Safety of Hepatic Artery Infusion Chemotherapy Combined with Donafenib and Camrelizumab in the Treatment of Patients with Unresectable Hepatocellular Carcinoma: A Retrospective, Single-Arm Study

Journal of Hepatocellular Carcinoma
Chenrui Wu,1,* Zixuan Fu,1,* Long Pan,1 Jiachu Li,2 Yin Zhou,3 Ruirui Sun,1 Yang Gou,1 Yaowu Zhao,1 Zhouyan Wang,1 Yuhao Qiu,1 Ping Huang1 1Department of Hepatobiliary Surgery, First Affiliated Hospital of Chongqing Medical University ...
Wu C, Fu Z, Pan L, Li J, Zhou Y, Sun R, Gou Y, Zhao Y, Wang Z, Qiu Y, Huang P   +10 more
doaj  

Medication prescription patterns in cancer rehabilitation physiatry outpatients: A multicenter retrospective study

PM&R, EarlyView.
Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen, Nafis Eghrari, David Leong, Philip Chang, Jasmine Zheng, Amy Ng, Richard Wilson, Mary Vargo   +7 more
wiley   +1 more source

Current best evidence in pigmentary dermatology

Pigment International
Priyansh Gupta, Priyanka Sangwan, Muthu Sendhil Kumaran   +2 more
doaj   +1 more source

Nanoparticle polymeric micellar paclitaxel compared with paclitaxel for advanced esophageal squamous cell carcinoma

Precision Medical Sciences, EarlyView.
The nanoparticle polymeric micellar paclitaxel plus nedaplatin regimen demonstrates superior efficacy and tolerable toxicities compared to the paclitaxel–nedaplatin combination as a first‐line treatment for advanced esophageal squamous cell carcinoma.
Yu‐Qing Cao, Meng Song, Bing‐jie Xue, Fei‐Yu Wang, Xiang‐Ming Huang, Jie Cao, Ai‐Guo Cao, Xin‐En Huang   +7 more
wiley   +1 more source

Intelligent nano‐platforms in breast cancer therapy: Current advances and future perspectives

Precision Medical Sciences, EarlyView.
The smart nano platform in breast cancer treatment is designed with advanced nanocarriers, including liposomes, hydrogels, porous nanoparticles, and aptamer‐based systems. These systems are capable of targeted drug release and response to environmental stimuli.
Tina Rahimi, Moluk Aivazi
wiley   +1 more source