Results 101 to 110 of about 107,610 (251)
VIEW, EarlyView.Pancreatic ductal adenocarcinoma exhibits marked angiogenic and immune heterogeneity. We identified 28 angiogenesis‐associated immune genes and developed a seven‐gene AIGScore model comprising FGF2, ADGRB3, MMP2, TYMP, VASH1, VEGFD, and ITGAV. A high AIGScore was associated with poor survival, an immunosuppressive tumor microenvironment, and reduced ...
Qing Chang +4 more
wiley +1 more source
A Prediction Model for the Differential Diagnosis of Bowen's Disease and Bowenoid Actinic Keratosis
The Journal of Dermatology, EarlyView.ABSTRACT Bowen's disease and bowenoid actinic keratosis share overlapping clinical and histopathological features, and there is no clear consensus regarding their differential diagnosis. This study aimed to identify clinicopathological differences between the two diseases and to develop a diagnostic prediction model in a Korean population.
Byeonghyun Joo +6 more
wiley +1 more source
Protective Effect of Oleuropein on 5-Fluorouracil-Induced Ovarian Damage [PDF]
Journal of Ardabil University of Medical SciencesBackground: 5-fluorouracil is one of the chemotherapy drugs that has destructive effects on body tissues such as the heart, liver, kidney, brain and reproductive system in humans and animals. Reproductive dysfunction is considered to be an important side
Mahshid Khajavi +3 more
doaj
Asia-Pacific Journal of Clinical Oncology, EarlyView.In advanced rectal cancer patients receiving total neoadjuvant therapy (TNT), overall tumor response did not differ by diabetes status or metformin use. However, among diabetic patients, metformin use was associated with higher overall complete response rates. These findings suggest a potential benefit of metformin in enhancing TNT response in diabetic
Sergei Bedrikovetski +7 more
wiley +1 more source
Asia-Pacific Journal of Clinical Oncology, EarlyView.This study investigated the real‐world use of CDK4/6 inhibitors in Australian patients with HR+/HER2‐ advanced or metastatic breast cancer, providing data on patient demographics, treatment patterns, and outcomes with palbociclib. ABSTRACT Background There is limited real‐world data on the use of CDK4/6 inhibitors in Australian patients with HR+/HER2 ...
Louise Nott +8 more
wiley +1 more source
Asia-Pacific Journal of Clinical Oncology, EarlyView.There is limited understanding of the impact of underlying RAS/RAF mutational status on total neoadjuvant therapy metastatic tumor response rates in curative Stage IV rectal cancer patients. Complete metastatic tumor response to TNT was demonstrated in half as many mRAS as wtRAS patients and disease progression was higher in patients harboring RAS ...
Tracy R. Fitzsimmons +8 more
wiley +1 more source
Local Injections of Fluorouracil for Eyelid Hordeolum. [PDF]
Plast Reconstr Surg Glob OpenQin M +6 more
europepmc +1 more source
ANZ Journal of Surgery, EarlyView.ABSTRACT Background There is compelling evidence that treating high‐grade squamous intraepithelial lesions (HSIL), the anal squamous cell cancer (ASCC) precursor, reduces the risk of developing ASCC. Using high‐resolution anoscopy (HRA), surgical excision, ablative and topical therapies are widely used to treat HSIL.
Matthew Joseph Marino +5 more
wiley +1 more source
Plasma 5-Fluorouracil Exposure, Clinical Outcomes, and Therapeutic Drug Monitoring in Advanced Colorectal Cancer. [PDF]
Cancers (Basel)Sakuyama N +4 more
europepmc +1 more source
Direct comparison of efficacy of combining ivermectin versus five first-line chemotherapy drugs with recombinant methioninase against colon-cancer cells. [PDF]
Front OncolKim J +7 more
europepmc +1 more source