Results 131 to 140 of about 174,614 (242)

Application of high‐dose‐rate endorectal brachytherapy in the treatment of locally advanced rectal cancer

Precision Radiation Oncology, EarlyView.
This image compares the studies included in this article with the meta‐analysis from the Cochrane Library, indicating that the incorporation of brachytherapy in neoadjuvant treatment for rectal cancer can achieve better pathological response rates. Additionally, the use of brachytherapy can reduce the local recurrence rate in patients.
Tianyao Wang, Yifan Tao, Guanghui Gan, Long Chen, Yuan Xu, Fei Sun, Xiaoting Xu   +6 more
wiley   +1 more source

Oleanolic acid enhanced the anticancer effect of fluorouracil by regulating Ca2+ levels in hepatocellular carcinoma cells. [PDF]

Braz J Med Biol Res
Dong J, Gao Y, Li P, Chen P, Lv Y, Liu Y, Zhang S, Zhang M, Wang Y.   +8 more
europepmc   +1 more source

Mechanistic Learning for Predicting Survival Outcomes in Head and Neck Squamous Cell Carcinoma

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 540-550, March 2025.
ABSTRACT We employed a mechanistic learning approach, integrating on‐treatment tumor kinetics (TK) modeling with various machine learning (ML) models to address the challenge of predicting post‐progression survival (PPS)—the duration from the time of documented disease progression to death—and overall survival (OS) in Head and Neck Squamous Cell ...
Kevin Atsou, Anne Auperin, Jôel Guigay, Sébastien Salas, Sebastien Benzekry   +4 more
wiley   +1 more source

Controlled release of 5-fluorouracil from microporous zeolites [PDF]

, 2014
Bouropoulos, Nikolaos, Cox, Paul A., Ewart, Sinead, Fatouros, Dimitrios G., Kachrimanis, Kyriakos, Moschovi, Anastasia Maria, Nikolakis, Vladimiros, Niopas, Ioannis, Siokou, Angeliki, Spanakis, Marios, Sygellou, Lamprini, Theodoropoulos, Dimitrios, Vizirianakis, Ioannis S.   +12 more
core   +1 more source

Metastatic pancreatic acinar cell carcinoma with <i>BRCA2</i> gene alternation resected after modified FORFIRINOX therapy: a case report and literature review. [PDF]

J Gastrointest Oncol
Sugata S, Yamaguchi A, Kamada H, Semba S, Kato N, Teraoka Y, Mizumoto T, Tamaru Y, Hatakeyama T, Kouno H, Shibata Y, Tazuma S, Sudo T, Yamamoto R, Kuraoka K, Yoshida S, Oka S.   +16 more
europepmc   +1 more source

Nucleic Acid‐Modified Nanoparticles for Cancer Therapeutic Applications

Small, EarlyView.
Nucleic acid‐modified nanoparticles act as functional hybrids for chemodynamic, photodynamic, photothermal, and gene therapy of cancer cells. These are exemplified with aptamer‐modified catalytic nanoparticles, photosensitizer‐oligonucleotide functionalized nanoparticles, drug‐loaded stimuli‐responsive nucleic acid‐caged nanoparticle carriers, and ...
Yunlong Qin, Xinghua Chen, Itamar Willner   +2 more
wiley   +1 more source

Differential Effects of Rutin and Its Aglycone Quercetin on Cytotoxicity and Chemosensitization of HCT 116 Colon Cancer Cells to Anticancer Drugs 5-Fluorouracil and Doxorubicin. [PDF]

Biology (Basel)
Suman I, Jezidžić A, Dobrić D, Domitrović R.   +3 more
europepmc   +1 more source

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

Small, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai, Dhwani Rana, Mitali Patel, Neha Bajwa, Rajendra Prasad, Lalitkumar K. Vora   +5 more
wiley   +1 more source

Combination of 5-Fluorouracil and Thymoquinone for Enhanced Cytotoxicity, Genotoxicity and Apoptosis In Colorectal Cancer: In Vitro and In Vivo Studies. [PDF]

J Biochem Mol Toxicol
Guler EM, Bozali K, Huseyinbas O, Celikten M, Kocyigit A.   +4 more
europepmc   +1 more source

Nanomedicine Approaches for Autophagy Modulation in Cancer Therapy

Small Science, EarlyView.
Autophagy modulation holds promise for enhancing cancer treatment, yet clinical translation remains challenging. This review explores nanomedicine‐based strategies to improve autophagy‐targeting drugs, highlighting their synergy with chemotherapy, immunotherapy, phototherapy, and gene therapy. It also discusses nanoparticle design and clinical progress,
Sohaib Mahri, Rodolfo Villa, Ya‐Ping Shiau, Menghuan Tang, Kelsey Jane Racacho, Qiufang Zong, Saiful Islam Chowdhury, Tan Hua, Felipe Godinez, Andrew Birkeland, Tzu‐Yin Lin, Yuanpei Li   +11 more
wiley   +1 more source