Results 151 to 160 of about 107,610 (251)

Inhibition of P‐glycoprotein using photoimmunotherapy in peritoneal metastasis mouse model

Photochemistry and Photobiology, EarlyView.
Photoimmunotherapy (PIT) using photoimmunoconjugates (PICs) can inhibit the function of the ATP‐binding cassette (ABC) transporter P‐glycoprotein (P‐gp) in a mouse model of peritoneal carcinomatosis. Sterile‐filtered PIC was administered in vivo via intraperitoneal (IP) injection 20 days after IP tumor cell implantation of P‐gp‐overexpressing NCI/ADR ...
Kaitlyn A. Moore, Brian Schnoor, Kathryn L. McNaughton, Idrisa Rahman, Benjamin D. Powers, Dana M. Roque, Huang‐Chiao Huang   +6 more
wiley   +1 more source

Complete Response with Modified FLOX in Metastatic Colon Cancer: A Case Report

Journal of Coloproctology
Denis Artico Galhera, Camila Motta Venchiarutti Moniz   +1 more
doaj   +1 more source

Retraction: Real-World Outcomes of Peri-Operative Chemotherapy With Fluorouracil, Leucovorin, Oxaliplatin, and Docetaxel in Upper Gastrointestinal Cancers: An Audit of Patients Diagnosed Between 2017 and 2020 at the Christie Hospital. [PDF]

Cureus
Sabry M, Mahmoud Y, Hatahet Y, Patel R, Ibrahim N.   +4 more
europepmc   +1 more source

Understanding Exosomes in Hair Regeneration

Periodontology 2000, EarlyView.
Abstract Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome‐mediated interventions as a novel cell‐free regenerative approach for hair ...
Paras Ahmad, Catherine Davies, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Formulation of 5-fluorouracil loaded chitosan-based nanoparticles and evaluation of its cytotoxic effects against MCF-7 human breast cancer cells. [PDF]

PLoS One
Ekpo IA, Ovenseri AC, Abdullateef A, Durmaz B.   +3 more
europepmc   +1 more source

Pathophysiology of the gut–eye axis in a Sjögren's disease‐like dry eye mouse model: An exploratory evaluation of dietary heat‐treated Enterococcus faecalis FK‐23

Experimental Physiology, EarlyView.
Abstract Sjögren's disease is an autoimmune disease characterized by severe dry eye, but its pathophysiology remains unclear. Non‐obese diabetic (NOD) mice develop Sjögren's disease‐like dry eye prior to the onset of diabetes. Although intestinal immune abnormalities precede diabetes in NOD mice, their relationship to dry eye remains poorly understood.
Kenji Goto, Shigekazu Takemura, Yukiko Minamiyama, Toshikazu Yoshikawa   +3 more
wiley   +1 more source

The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity

The Journal of Physiology, EarlyView.
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas, Debbie J. Otto, Daniel Stratton, Katja Rietdorf, Daniel M. Johnson, Calum J. McMullen   +5 more
wiley   +1 more source

Thymoquinone and pentoxifylline modulate 5-fluorouracil-induced senescence and apoptosis in colorectal cancer spheroids. [PDF]

Res Pharm Sci
Makalani F, Ghanbari A, Tabandeh MR, Nasta TZ, Souq AJ, Jalili C.   +5 more
europepmc   +1 more source

Transpapillary Placement of a Multihole Covered Metal Stent Using a 5.9‐Fr Delivery System Through a Forward‐viewing Endoscope in Malignant Biliary Obstruction With Type I Duodenal Stenosis

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Concurrent malignant biliary obstruction (MBO) and type I duodenal stenosis represent a technically demanding scenario, as luminal narrowing frequently precludes passage of a standard side‐viewing duodenoscope and limits conventional transpapillary drainage.
Kengo Matsumoto, Daisuke Kondo, Satoru Okabe, Naoto Osugi, Akira Doi, Masashi Yamamoto, Shiro Hayashi, Koji Fukui, Tsutomu Nishida   +8 more
wiley   +1 more source

Cyclodextrin-Based Nanocarriers for 5-Fluorouracil: Cholesteryl Modification Enhances Antitumor Activity Against Colorectal Cancer Cells. [PDF]

Int J Nanomedicine
Skonieczna B, Maliszewski B, Wasiluk N, Car H, Wilczewska AZ, Misiak P, Niemirowicz-Laskowska K.   +6 more
europepmc   +1 more source