Results 131 to 140 of about 142,003 (296)

The antiangiogenic properties of sulfated β-cyclodextrins in anticancer formulations incorporating 5-fluorouracil

, 2013
Sulfated β-cyclodextrins (S-β-CDs) are useful excipients for improving the solubility of drugs. One such formulation incorporating 5-fluorouracil (5-FU), termed FD(S), showed improved efficacy over 5-FU alone in orthotopic carcinoma xenograft models. S-β-
Marie Ranson (19586413), Anna Bezos (678524), Christopher R Parish (20212950), Clare Watson (20126469), Julie Locke (20117169), Kara Perrow (19585660)   +5 more
core   +1 more source

Core-Shell Magnetic Nanocarriers: Fe3O4-Hydroxyapatite/Polysuccinimide Hybrids for Enhanced Oral Bioavailability of Fluorouracil

International Journal of Nanomedicine
Wenhui Zhang,1 Qiang Wang,2 Fengguo Zhai,1 Xingjun Fan,3 Fanqin Meng,1 Guangzhi Shen,1 Ying Zhu,1 Jingdan Cao,1 Fengbo Yu1 1School of Pharmacy, Mudanjiang Medical University, Mudanjiang, 157011, People’s Republic of China; 2Hongqi People Hospital ...
Zhang W, Wang Q, Zhai F, Fan X, Meng F, Shen G, Zhu Y, Cao J, Yu F   +8 more
doaj  

Correction to "Long Noncoding RNA OVAAL Enhances Nucleotide Synthesis Through Pyruvate Carboxylase to Promote 5-Fluorouracil Resistance in Gastric Cancer". [PDF]

Cancer Sci
Cancer Science, EarlyView.
europepmc   +2 more sources

Dihydropyrimidine Dehydrogenase Genotype–Phenotype Correlations in Plasma and Peripheral Blood Mononuclear Cells

Clinical Pharmacology &Therapeutics, EarlyView.
The chemotherapeutic 5‐fluorouracil (5‐FU) is commonly used to treat solid tumors, especially colorectal cancer. Deleterious variants in DPYD, which encodes dihydropyrimidine dehydrogenase (DPD), are strongly associated with severe and potentially lethal 5‐FU toxicity.
Brianna M. Bembenek, Seid Hamzic, Kelly J. Bouchonville, Carlo R. Largiadèr, Steven M. Offer   +4 more
wiley   +1 more source

Chronotherapy with 5-Fluorouracil and Folinic Acid in Advanced Colorectal Carcinoma [PDF]

, 1994
Hallek, M., Emmerich, B., Lang, S., Langenmayer, Irmgard, Rump, W., Eibl-Eibesfeldt, B., Adler, S.   +6 more
core   +1 more source

“Nature's Polymer Reimagined: Conventional and Green Routes to Pectin, Its Bioactive Promise and Industrial Applications”

Food Chemistry International, EarlyView.
Pectin, a versatile natural polymer, is extracted through conventional and emerging green extraction methods, offering multifunctional bioactive properties useful in food, pharmaceutical, and environmental applications. ABSTRACT Pectin, a molecular tapestry woven from diverse polysaccharides, holds a pivotal role across food, pharmaceutical, and ...
Afra Anika Rafique, Aunwesha Sahani, Md Morsaline Billah, Kazi Mohammed Didarul Islam   +3 more
wiley   +1 more source

Application of chemotherapy combined with immunotherapy in first-line treatment of advanced esophageal cancer: fluorouracil or paclitaxel? – a meta-analysis

Frontiers in Oncology
IntroductionImmunotherapy combined with chemotherapy is now the first-line standard for metastatic/recurrent esophageal cancer, with rapid immunotherapy advancements significantly improving patient outcomes.
Xiaochen Chen, Xiaochen Chen, Huiping Yan, Hongyang Zhao, Pengfei Zhu   +4 more
doaj   +1 more source

Head and Neck Lymph Node Metastases From Cancer of Unknown Primary: Outcomes From p16‐Guided Mucosal Radiotherapy

Head &Neck, EarlyView.
ABSTRACT Background The AJCC 8th edition distinguishes p16‐positive oropharyngeal head and neck carcinoma of unknown primary (HNCUP) due to its superior prognosis. However, standardized radiation volume guidelines are lacking. This study evaluates the safety of p16‐guided mucosal volume reduction.
Philippe Harris, Dhiya‐Eddine Mabrouki, Felix‐Phuc Nguyen‐Tan, Edith Filion, Olivier Ballivy, Brian O'Sullivan, Apostolos Christopoulos, Tareck Ayad, Louis Guertin, Eric Bissada, Paul Tabet, Denis Soulières, Antoine Desilets, Alexandre Pellan Cheng, Robert Doucet, Laurent Létourneau‐Guillon, Houda Bahig   +16 more
wiley   +1 more source

Trismus and Health‐Related Quality of Life in HNC Patients up to 10 Years Post‐Radiotherapy Completion

Head &Neck, EarlyView.
ABSTRACT Background This prospective study investigates trismus prevalence, quality of life (QOL), and trismus‐related symptoms in HNC patients up to 10 years post‐radiotherapy (RT). Methods A total of 211 patients with HNC receiving RT were followed pretreatment, 12, 60, and 120 months post‐RT.
Therese Karlsson, Lisa Tuomi, Caterina Finizia   +2 more
wiley   +1 more source

Postoperative electrocardiography changes: To worry or not to worry

Annals of Noninvasive Electrocardiology
Abnormal postoperative electrocardiograms are not uncommon, oftentimes leading to further cardiac workup especially when the findings are new and not easily explainable.
Chihjen Lee, Janet Shin, Arash Bereliani, Liza Capiendo, Eiman Firoozmand, Roya Yumul   +5 more
doaj   +1 more source