Results 251 to 260 of about 290,304 (371)

Hepatic arterial infusion is effective in patients with unresectable colorectal liver metastases refractory to standard systemic chemotherapy: A retrospective cohort study. [PDF]

PLoS One
Ishii M, Itano O, Iwamoto H, Takami Y, Okada N, Inoue T, Itano S.   +6 more
europepmc   +1 more source

Long-term sequelae of Palmar-Plantar erythrodysaesthesia syndrome secondary to 5-fluorouracil therapy.

, 1995
G. Banfield, I D Crate, Carrie L. Griffiths   +2 more
openalex   +1 more source

Targeting Genome Maintenance Defects of Cancers Using Chain‐Terminating Nucleoside Analogs

Cancer Science, EarlyView.
Nucleoside analogs interfere with DNA replication either by their chain‐terminating properties or by serving as DNA damage on the template. The genome maintenance pathways required to maintain cellular tolerance to each nucleoside analog vary depending on the drug.
Ryotaro Kawasumi, Rubaiat E. Tabassum, Kouji Hirota   +2 more
wiley   +1 more source

Optimal neoadjuvant regimens for locally advanced gastric and gastroesophageal junction cancer: a systematic review and bayesian network meta-analysis. [PDF]

World J Surg Oncol
Fan WQ, Wu YT, Li H, Xu H, Zhu YY, Cheng YR, Peng YH.   +6 more
europepmc   +1 more source

368eP Real-world outcomes of nanoliposomal irinotecan plus fluorouracil in second-line treatment of advanced pancreatic cancer: A multicenter retrospective study from Thailand [PDF]

T. Thambamroong, Chirawadee Sathitruangsak, Suebpong Tanasanvimon, W. Laosuangkoon, R. Meesart, Nuttapong Ngamphaiboon, Naiyarat Prasongsook, N. Pakvisal, Charuwan Akewanlop, Krittiya Korphaisarn, T. Suksombooncharoen, Chanchai Charonpongsuntorn, S. Sa-Nguansai, Teerada Siripoon, Kosin Wirasorn, E. Sirachainan   +15 more
openalex   +1 more source

Decoding Senescence‐Driven Heterogeneity in Early‐Onset Colorectal Cancer for Prognostic and Therapeutic Stratification

Cancer Science, EarlyView.
We uncovered pronounced and heterogeneous tumor senescence in EOCRC, independent of age. By integrating multi‐omics and single‐cell analyses, we developed EO‐Senscore, a prognostic tool that stratifies patients by immune phenotype and therapy response, enabling precision treatment using immunotherapy or senolytic agents. ABSTRACT Early‐onset colorectal
Du Cai, Mingru Mai, Rende Huang, Haoning Qi, Xingzhi Feng, Qianling Gao, Yinmeng Zhang, Chenghang Li, Xiaojian Wu, Yize Mao, Zihuan Yang, Feng Gao   +11 more
wiley   +1 more source

Complete Response with Modified FLOX in Metastatic Colon Cancer: A Case Report

Journal of Coloproctology
Denis Artico Galhera, Camila Motta Venchiarutti Moniz   +1 more
doaj   +1 more source

Beta-Blockers as Potential Adjuvants in Melanoma Treatment. [PDF]

Toxics
Rama L, Almeida M, Jose J, Pereira ML, Oliveira M.   +4 more
europepmc   +1 more source

SUSD2 Promotes Metastasis and Primary Tumor Growth in Pancreatic Cancer Cells via Integrin–FAK Signaling Activation

Cancer Science, EarlyView.
This study investigates the role of Sushi domain‐containing 2 (SUSD2) in pancreatic ductal adenocarcinoma (PDAC) and demonstrates that SUSD2 enhances both metastasis and primary tumor growth by promoting integrin β1–FAK signaling. SUSD2 interacts with integrin β1, enhancing adhesion to extracellular matrix (ECM) components such as collagen 1 and ...
Junjiro Yoshida, Tomokazu Ohishi, Isao Momose, Shun‐ichi Ohba, Kyohei Kurosawa, Akiko Harakawa, Hiroyuki Inoue, Minori Senoo, Daisuke Tatsuda, Hikaru Abe, Atsushi Masamune, Manabu Kawada   +11 more
wiley   +1 more source

Prevalence of uncommon side effects of 5-fluorouracil and capecitabine in Saudi patients with cancer: A cross-sectional observational study. [PDF]

Medicine (Baltimore)
Aljadeed R, Altuwaijri N, Almalag HM, Alnaim LS, Alanazi NH, Alsaweed LA, Al Aloola N, Alsabhan JF, Bawazeer GA, Al Juffali L, Alkofide H, Alfaraj R, Alkhudair N, Aljadeed R, Almoghirah H, Alkhelb DA, Almohaimeed R.   +16 more
europepmc   +1 more source