Results 71 to 80 of about 283,224 (387)

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

Advanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham, Jose Gabriel Castro, Lisette C. Werba, Joseph Amitrano, Luke Fardone, Kevin P. Francis, Anand Ramamurthi, Michael J. Layden, Helen O. McCarthy, Tomas Gonzalez‐Fernandez   +9 more
wiley   +1 more source

Resistance of gloves and protective clothing materials to permeation of cytostatic solutions

International Journal of Occupational Medicine and Environmental Health, 2018
Objectives The objective of the work was to determine the resistance of selected protective clothing and glove materials to permeation of cytostatics such as docetaxel, fluorouracil, and doxorubicin.
Sylwia Krzemińska, Małgorzata Pośniak, Małgorzata Szewczyńska   +2 more
doaj   +1 more source

Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy [PDF]

, 2017
BACKGROUND. Actinic keratosis is a precursor to cutaneous squamous cell carcinoma. Long treatment durations and severe side effects have limited the efficacy of current actinic keratosis treatments.
Ahu Turkoz, Andras Schaffer, Arturo P. Saavedra, Cipolat, Fenske, Hengameh Mirzaalian, Jean-Pierre Eliane, Lynn A. Cornelius, Mary Tabacchi, Michael Wallendorf, Raphael Kopan, Salasche, Sara Moradi Tuchayi, Seckin, Shadmehr Demehri, Sindhu Manivasagam, Stockfleth, Trevor J. Cunningham, Warino   +18 more
core   +2 more sources

Metal Nanoclusters for Cancer Imaging and Treatment

Advanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu, Ziping Wang, Qiaofeng Yao, Ping Zhang, Jianping Xie, Xun Yuan   +5 more
wiley   +1 more source

Advanced Oral Delivery Systems for Nutraceuticals

Advanced Healthcare Materials, EarlyView.
Emerging delivery technologies are explored to overcome barriers to oral nutraceutical absorption. Traditional carriers are compared with novel platforms including biodegradable polymers, MOFs, MPNs, and 3D printing. These systems enhance bioavailability, control release, and enable personalized nutrition.
Xin Yang, Linzixuan Zhang, Zhiling Zheng, Robert Langer, Ana Jaklenec   +4 more
wiley   +1 more source

Filtering bleb activation in the early post-operative period after fistulizing surgery

Oftalʹmologiâ, 2014
The article presents a case report of a patient with a cystic bleb in the early postoperative period after trabeculectomy. Patient complained of discomfort in a recently (4 weeks) operated eye.
S. Yu. Petrov, A. A. Antonov, S. V. Vostrukhin, L. A. Panyushkina, D. M. Safonova   +4 more
doaj   +1 more source

Chemo-immune synergetic therapy of esophageal carcinoma: trastuzumab modified, cisplatin and fluorouracil co-delivered lipid–polymer hybrid nanoparticles

Drug Delivery, 2020
Esophageal cancer is the sixth most common cause of cancer-related death worldwide. Peptide modified nanoparticles have been engineered as novel strategies to improve esophageal adenocarcinoma (EAC) therapy. This study aimed to develop a trastuzumab (TAB)
Qingxia Fu, Jiancheng Wang, Hong Liu
doaj   +1 more source

Feasibility and morbidity of combined hyperthermia and radiochemotherapy in recurrent rectal cancer - Preliminary results [PDF]

, 2003
Background: The local recurrence rate of colorectal cancer has been significantly reduced due to the use of combined radiochemotherapy. Despite this improvement regarding locally advanced tumour recurrences, the treatment strategy for pre-treated ...
Abdel-Rahman, Sultan, Dühmke, Eckhart, Ertl-Wagner, Birgit, Issels, Rolf-Dieter, Krych, M., Pachmann, S., Schaffer, Moshe, Schaffer, Pamela Manuela   +7 more
core   +1 more source

Transforming Cancer Diagnosis and Therapy Through Fluorescent Hydrogels: A Review

Advanced Healthcare Materials, EarlyView.
This article reviews fluorescent hydrogel systems for cancer detection, monitoring, and therapy. Mimicking the tumor microenvironment, these hydrogels enable real‐time imaging and targeted drug delivery. The review discusses design strategies, labeling techniques, and applications, highlighting challenges and future opportunities in cancer diagnostics ...
Elahe Masaeli, Seshasai Srinivasan, Amin Reza Rajabzadeh   +2 more
wiley   +1 more source

Visual acuity after trabeculectomy [PDF]

Vojnosanitetski Pregled, 2005
Background/Aim. In this study we compared the two groups of glaucoma patients who had underwent trabeculectomy, with or without intraoperative application of antimetabolite 5-Fluorouracile (5 FU). Methods. We followed up 50 glaucoma patients (group I) in
Buzarovska-Blaževska Karolina, Jordanova-Dimovska Vesna, Vukosavljević Miroslav, Džajkovska Elena   +3 more
doaj   +1 more source