Results 111 to 120 of about 90,654 (272)

3,4‐Methylenedioxymethamphetamine (MDMA) does not induce robust psychomotor activation and 50‐kHz ultrasonic vocalisations in tryptophan hydroxylase 2 (Tph2)‐deficient rats lacking serotonin in the central nervous system

British Journal of Pharmacology, EarlyView.
Background and Purpose 3,4‐Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy, is a psychostimulant with entactogenic properties and known to induce arousal and euphoria. As an amphetamine derivate, MDMA acts on the monoamine systems in the brain and stimulates release of dopamine (DA), noradrenaline (NA) and serotonin (5‐HT), yet their ...
Tianhua Wang, Rainer K. W. Schwarting, Markus Wöhr   +2 more
wiley   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, EarlyView.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

Fluoxetine prevents Aβ1-42-induced toxicity via a paracrine signaling mediated by Transforming-Growth-Factor-β1

Frontiers in Pharmacology, 2016
Selective reuptake inhibitors (SSRIs), such as fluoxetine and sertraline, increase circulating Transforming-Growth-Factor-β1 (TGF-ß1) levels in depressed patients,and are currently studied for their neuroprotective properties in Alzheimer’s disease (AD).
Filippo Caraci, Filippo Caraci, Fabio Tascedda, Sara Merlo, Cristina Benatti, Simona Federica Spampinato, Antonio Munafò, Gian Marco Leggio, Ferdinando Nicoletti, Ferdinando Nicoletti, Nicoletta Brunello, Filippo Drago, Maria Angela Sortino, Agata Copani, Agata Copani   +14 more
doaj   +1 more source

Dexfenfluramine, Fluoxetine, and Weight Loss Among Female Carbohydrate Cravers [PDF]

, 1993
Judith J. Wurtman, Richard J. Wurtman, Eliot Berry, Ray E. Gleason, Hannah Goldberg, J Mcdermott, Merton J. Kahne, Rita Tsay   +7 more
openalex   +1 more source

Adjuvant Use of Melatonin with Fluoxetine for Management of Fibromyalgia

Medicine Science, 2013
Fibromyalgia (FMS) is a chronic musculoskeletal disorder characterized by generalized muscular pain and tenderness at specific anatomical sites. Although melatonin was effective in treating the pain associated with this syndrome, no defined clinical ...
Saad Abdulrahman Hussain, Ihab Ibrahim Alkhalifa, Nizar Abdullateef Jassim   +2 more
doaj   +1 more source

A Placebo Controlled Crossover Trial of Liquid Fluoxetine on Repetitive Behaviors in Childhood and Adolescent Autism [PDF]

, 2004
Eric Hollander, Ann Phillips, William F. Chaplin, Karen Zagursky, Sherie Novotny, Stacey Wasserman, Rupa Iyengar   +6 more
openalex   +1 more source

Reasons for patient reluctance to take preventive medications for migraine: Results of the OVERCOME (US) study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This study was undertaken to evaluate patient reasons for nonadoption of migraine‐preventive medications. Despite clear recommendations and eligibility criteria for migraine‐preventive treatment by the American Headache Society and the availability of these treatments, many people with migraine are not taking appropriate ...
Jessica Ailani, Rose Okonkwo, Elizabeth Johnston, Helen Hochstetler, Betzaida Martinez, Anthony Zagar, Robert A. Nicholson, Bert B. Vargas, E. Jolanda Muenzel, Richard B. Lipton   +9 more
wiley   +1 more source

The serotonin reuptake inhibitor Fluoxetine inhibits SARS-CoV-2 [PDF]

, 2020
Melissa Zimniak, Luisa Kirschner, Helen Hilpert, Jürgen Seibel, Jochen Bodem   +4 more
openalex   +1 more source

Antipsychotic Use Among Intellectually Disabled Individuals With Rare Genetic Variants That Confer Risk for Schizophrenia

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Rare genetic variation can predispose individuals to the development of schizophrenia, with certain genes and copy number variants (CNVs) conferring risk at the exome/genome‐wide level. Despite this strong association, little is known about antipsychotic effectiveness and tolerability among individuals with most of these disorders ...
Mark Ainsley Colijn
wiley   +1 more source

Effect of Anti-stress Activity of Fluoxetine on Restrained Stress Induced Male Albino Rats in Hematological Parameters and Whole Brain Histopathology [PDF]

, 2017
Rohini S. Kori, Ravindranath H. Aladkatti, Soaham Desai, Kusal K. Das   +3 more
openalex   +1 more source