Results 111 to 120 of about 80,403 (271)

Fluoxetine protection in decompression sickness in mice is enhanced by blocking TREK-1 potassium channel with the spadin antidepressant.

Frontiers in Physiology, 2016
In mice, disseminated coagulation, inflammation and ischemia induce neurological damages that can lead to the death. These symptoms result from circulating bubbles generated by a pathogenic decompression.
Nicolas eVallée, Kate eLambrechts, Kate eLambrechts, Sébastien eDe Maistre, Perrine eRoyal, Jean eMazella, Marc eBorsotto, Catherine eHeurteaux, Jacques eAbraini, Jacques eAbraini, Jacques eAbraini, Jean-Jacques eRisso, Jean-Eric eBlatteau   +12 more
doaj   +1 more source

Polypharmacy among adolescents and adults with cerebral palsy in a clinical setting

PM&R, EarlyView.
Abstract Background Adolescents and adults with cerebral palsy often experience multimorbidity related to their condition, which primarily affects movement and posture but is also associated with pain, epilepsy, mood disorders, and other conditions. As such, these patients are often prescribed a range of medications to manage symptoms, thereby putting ...
Caitlin Cassidy, Joshua C. Wiener, Karen Pratt, Laura Brunton   +3 more
wiley   +1 more source

De novo TANC2 stop‐loss variant associated with developmental impairment and drug‐resistant epilepsy

Epileptic Disorders, EarlyView.
Matthew A. Hintermayer, Kenneth A. Myers
wiley   +1 more source

Comparative Efficacy of Elinzanetant Versus Other Non‐Hormonal Pharmaceutical Therapies for the Treatment of Moderate‐to‐Severe Vasomotor Symptoms Associated With Menopause: A Network Meta‐Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Elinzanetant, a novel, dual neurokinin‐targeted therapy, has been approved in various geographies for the treatment of moderate‐to‐severe vasomotor symptoms (VMS) associated with menopause. Objective To compare the efficacy of elinzanetant with non‐hormonal pharmaceutical treatments (nHT) in alleviating VMS.
Piotr Wojciechowski, Klaudia Kolonko, Andromachi Giannopoulou, Beata Smela, Elżbieta Olewinska, Kristina Rosa Bolling, Jenifer Sassarini, Lee P. Shulman, Vikram Talaulikar   +8 more
wiley   +1 more source

Impacts of early intervention with fluoxetine following early neonatal immune activation on depression-like behaviors and body weight in mice [PDF]

Several reports have suggested that early neonatal immune activation adversely influences the hypothalamic– pituitary–adrenal (HPA) axis development in humans and animal models.
امانی, محمد, ببری, شیرین, بختیاری, امیر, دوستی, محمد حسین, زارع, پیمان, سالاری, علی اکبر, مجیدی ذوالبنین, نعیمه   +6 more
core   +1 more source

How Changing Food Preferences and Technology Are Transforming Food Markets

Journal of Agricultural Economics, EarlyView.
ABSTRACT The foods that consumers purchase and how they purchase food are changing over time. In this article, we discuss how health prioritization and environmental concerns, combined with new technologies, are changing consumers' food preferences and retail choices.
Jill J. McCluskey, Jillian Hyink
wiley   +1 more source

‘I, Me, Myself’: Selfhood and Melancholy in the Journals of Gertrude Savile (1697–1758)

Journal for Eighteenth-Century Studies, EarlyView.
Abstract This article examines the journals of Gertrude Savile from 1727 in light of recent scholarship on early modern and eighteenth‐century melancholy. The concept had myriad associations with medicine, physiology, the imagination, and feeling, but questions remain about how melancholy during this period was considered by those outside the narrow ...
Daniel Beaumont
wiley   +1 more source

Selective Serotonin Reuptake Inhibitor Treatment in Adolescence and Subsequent Risk of Nonaffective Psychosis: A Quasi‐Experimental Study

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Objective Psychotic disorders are frequently preceded by common mental disorders (CMDs), like depression and anxiety. It remains unclear whether treating CMDs in adolescence can reduce subsequent psychosis risk. We applied quasi‐experimental methods to national register data to assess whether a causal relationship exists between selective ...
Ioanna Kougianou, Animesh Talukder, Kirstie O′ Hare, Colm Healy, Ian Kelleher   +4 more
wiley   +1 more source

The association between the fluoxetine use and the occurrence of coronary heart disease: a nationwide retrospective cohort study

BMC Cardiovascular Disorders
Background We explored if the administration of fluoxetine, recognized for its potential in adipocyte browning, entails a differential risk of coronary heart disease (CHD) in comparison to other SSRI medications.
Fang-Ling Li, Yu-Tse Sheih, Ming-Hsun Lin, Yong-Chen Chen, Wen-Tung Wu, Tsung-Kun Lin, Yu‐Ching Chou, Chien‐An Sun   +7 more
doaj   +1 more source

Comparative effectiveness, safety and acceptability of pharmacological and psychosocial interventions for the treatment of cannabis use disorder: A network meta‐analysis

Addiction, EarlyView.
Abstract Aim Our primary aim was to conduct a network meta‐analysis (NMA) for the effectiveness, safety and acceptability of all psychosocial interventions and all pharmacotherapies for cannabis use disorder (CUD). Methods We conducted a NMA of studies identified from two completed systematic reviews examining the effectiveness, safety and ...
Monika Halicka, Francesca Spiga, Tom P. Freeman, Suzanne Nielsen, Jelena Savović, Julian P. T. Higgins, Deborah M. Caldwell   +6 more
wiley   +1 more source