Results 11 to 20 of about 47,292 (179)

Oxytocin exerts harmful cardiac repolarization prolonging effects in drug-induced LQTS

International Journal of Cardiology: Heart & Vasculature, 2022
Background: Oxytocin is used therapeutically in psychiatric patients. Many of these also receive anti-depressant or anti-psychotic drugs causing acquired long-QT-syndrome (LQTS) by blocking HERG/IKr.
Paul Kreifels, Ilona Bodi, Tibor Hornyik, Gerlind Franke, Stefanie Perez-Feliz, R. Lewetag, Robin Moss, Alessandro Castiglione, David Ziupa, Manfred Zehender, Michael Brunner, Christoph Bode, Katja E. Odening   +12 more
doaj   +1 more source

Open Channel Block of Kv3.1 Currents by Fluoxetine

Journal of Pharmacological Sciences, 2008
The action of fluoxetine, a serotonin reuptake inhibitor, on the cloned neuronal rat Kv3.1 channels stably expressed in Chinese hamster ovary cells was investigated using the whole-cell patch-clamp technique.
Min Ji Sung, Hye Sook Ahn, Sang June Hahn, Bok Hee Choi   +3 more
doaj   +1 more source

Impact of Fluoxetine on Behavioral Invigoration of Appetitive and Aversively Motivated Responses: Interaction With Dopamine Depletion

Frontiers in Behavioral Neuroscience, 2021
Impaired behavioral activation and effort-related motivational dysfunctions like fatigue and anergia are debilitating treatment-resistant symptoms of depression. Depressed people show a bias towards the selection of low effort activities. To determine if
Carla Carratalá-Ros, Laura López-Cruz, Andrea Martínez-Verdú, Régulo Olivares-García, John D. Salamone, Mercè Correa   +5 more
doaj   +1 more source

Study on anti-inflammatory and immunomodulatory effects of fluoxetine in rat models of inflammation

European Journal of Inflammation, 2015
The aim of the present study was to evaluate the anti-inflammatory effect of fluoxetine in carrageenan- and lipoplysaccharide-induced models of inflammation by investigating the changes in serum levels of pro-inflammatory cytokine TNF-α and anti ...
Ilia Kostadinov, Delian Delev, Atanaska Petrova, Irina Stanimirova, Krassimira Draganova, Peter Kruzliak, Ivanka Kostadinova, Marianna Murdjeva   +7 more
doaj   +1 more source

Effect of fluoxetine on cyclic adenosine monophosphate response to follicle-stimulating hormone in HEK cells

Veterinary Integrative Sciences, 2022
Fluoxetine is an antidepressant that acts as a selective serotonin reuptake inhibitor. Fluoxetine has exhibited different mechanisms of action on many different cell lines.
Thi Tho Nguyen, Thi Mong Diep Nguyen
doaj   +1 more source

The Possible Role of Fluoxetine in Adenomyosis: An Animal Experiment with Clinical Correlations [PDF]

Journal of Clinical and Diagnostic Research, 2013
Introduction: Fluoxetine is a commonly prescribed drug which is used in the psychiatric practice and adenomyosis is a common medical problem in women of the reproductive age group.
Parama Sengupta, Abhishek Sharma, Gautameswar Mazumdar, Indranil Banerjee, Santanu K Tripathi, Chiranjib Bagchi, Nina Das   +6 more
doaj   +1 more source

Fluoxetine-induced Hypotension: A Case Report

Pharmaceutical and Biomedical Research, 2023
Fluoxetine is a Selective Serotonin Reuptake Inhibitor (SSRI) that exerts its anti-depressive effect by blocking the presynaptic reuptake of the neurotransmitter serotonin, 5-hydroxytryptamine (5-HT).
Seyed Hamzeh Hosseini, Neda Zamani, Amirhossein Ahmadi   +2 more
doaj  

Fluoxetine attenuates neuroinflammation in early brain injury after subarachnoid hemorrhage: a possible role for the regulation of TLR4/MyD88/NF-κB signaling pathway

Journal of Neuroinflammation, 2018
Background Neuroinflammation is closely associated with functional outcome in subarachnoid hemorrhage (SAH) patients. Our recent study demonstrated that fluoxetine inhibited NLRP3 inflammasome activation and attenuated necrotic cell death in early brain ...
Fu-yi Liu, Jing Cai, Chun Wang, Wu Ruan, Guo-ping Guan, Hai-zhou Pan, Jian-ru Li, Cong Qian, Jing-sen Chen, Lin Wang, Gao Chen   +10 more
doaj   +1 more source

Morphological aspects of dentin-pulp complex development in the offspring of rats treated with fluoxetine during pregnancy

Brazilian Journal of Oral Sciences, 2015
Aim: To evaluate the morphological aspects of coronal dentinogenesis in the first molars of 1- and 5-day-old rats whose mothers were treated with fluoxetine hydrochloride during pregnancy.
Isabela Maria de Albuquerque Santiago, Luciana Silva Regueira, Priscylla Gonçalves Correia, Robério José Barbosa de Alcântara, Joaquim Evêncio Neto, Liriane Baratella-Evêncio   +5 more
doaj   +1 more source

Detecting fluoxetine and norfluoxetine in wild bird tissues and feathers

Environment International, 2019
The contamination of the environment with human pharmaceuticals is widespread and demand for such products is mounting globally. Wild vertebrates may be at particular risk from any effects from pharmaceuticals, because of the evolutionary conservation of
Sophia E. Whitlock, M. Glória Pereira, Julie Lane, Darren Sleep, Richard F. Shore, Kathryn E. Arnold   +5 more
doaj   +1 more source