Results 81 to 90 of about 105,140 (274)

Alleviation of the hepatotoxicity effects of fluoxetine using acetylcysteine with the royal jelly in rats

Egyptian Liver Journal
Background Fluoxetine is commonly used as the initial option for depressive symptoms and other neurological disorders. The repeated use of fluoxetine was related to hepatotoxicity and persistent liver disease.
Azad Hayal Nahy, Manal AbdulKhaliq Ibrahim, Manal N. Alhayder   +2 more
doaj   +1 more source

Study on the effect of fluoxetine against Candida albicans, alone or combined with fluconazole [PDF]

Kouqiang yixue
Objective To evaluate the inhibitory activity of fluoxetine alone and in combination with fluconazole on Candida albicans. Methods This study used standard strains of Candida albicans, clinical isolates of Candida albicans, and drug-resistant strains of ...
SHI Banruo, WU Qiaochu, MIAO Haochen, WEI Xin
doaj   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Serotonin reuptake inhibitors improve muscle stem cell function and muscle regeneration in male mice

Nature Communications
Serotonin reuptake inhibitor antidepressants such as fluoxetine are widely used to treat mood disorders. The mechanisms of action include an increase in extracellular level of serotonin, neurogenesis, and growth of vessels in the brain.
Mylène Fefeu, Michael Blatzer, Anita Kneppers, David Briand, Pierre Rocheteau, Alexandre Haroche, David Hardy, Mélanie Juchet-Martin, Anne Danckaert, François Coudoré, Abdulkarim Tutakhail, Corinne Huchet, Aude Lafoux, Rémi Mounier, Olivier Mir, Raphaël Gaillard, Fabrice Chrétien   +16 more
doaj   +1 more source

Biphasic Regulation of Caveolin-1 Gene Expression by Fluoxetine in Astrocytes: Opposite Effects of PI3K/AKT and MAPK/ERK Signaling Pathways on c-fos

Frontiers in Cellular Neuroscience, 2017
Previously, we reported that fluoxetine acts on 5-HT2B receptor and induces epidermal growth factor receptor (EGFR) transactivation in astrocytes. Recently, we have found that chronic treatment with fluoxetine regulates Caveolin-1 (Cav-1)/PTEN/PI3K/AKT ...
Baoman Li, Shu Jia, Tingting Yue, Li Yang, Chen Huang, Alexej Verkhratsky, Alexej Verkhratsky, Liang Peng   +7 more
doaj   +1 more source

Targeted monitoring for human pharmaceuticals in vulnerable source and final waters [PDF]

, 2012
A range of pharmaceuticals has been detected in soils, surface waters and groundwaters across the world. While the reported concentrations are generally low (i.e. sub μg l-1 in surface waters), the substances have been observed throughout the year across
Bersuder, Phillipe, Boxall, Alistair B.A., Bruemer, Janine, Fussell, Richard, Greenwood, Richard, Monteiro, Sara C., Williams, Richard J.   +6 more
core  

Developmental Fluoxetine Exposure Normalizes the Long-Term Effects of Maternal Stress on Post-Operative Pain in Sprague-Dawley Rat Offspring [PDF]

, 2013
Early life events can significantly alter the development of the nociceptive circuit. In fact, clinical work has shown that maternal adversity, in the form of depression, and concomitant selective serotonin reuptake inhibitor (SSRI) treatment influence ...
Charlier, E. (Erwin), Fillet, M. (Marianne), Houbart, V. (Virginie), Joosten, E.A. (Elbert), Kleef, M. (Maarten) van, Knaepen, L. (Liesbeth), Patijn, J. (Jacob), Pawluski, J.L. (Jodi), Rayen, I. (Ine), Steinbusch, H.W. (Harry), Tibboel, D. (Dick)   +10 more
core   +1 more source

Antidepressants and the risk of hyponatremia: A multi‐institutional cohort study using observational medical outcomes partnership—Common Data Model

British Journal of Clinical Pharmacology, EarlyView.
Aim Hyponatremia is a common yet potentially serious adverse event associated with antidepressants. Identifying the antidepressant class with the least risk of hyponatremia would improve patient safety. Methods Using electronic medical records from 15 hospitals standardized into Observational Medical Outcomes Partnership Common Data Model (2003–2023 ...
Kyungyeon Jung, Ju Hwan Kim, Da Eun Hyeon, Jeongmoon Ji, Min Young Lee, Hayun Choi, Dong Yun Lee, Min Woo Kim, Yoonmin Jang, Seonghoon Hwang, Jaehyeong Cho, Seok Young Song, Sang Youl Rhee, Jae Myung Cha, Won‐Woo Seo, Chang‐Won Jeong, Seung‐Jin Kwag, Woo Jin Kim, Jaeuk Hwang, Min‐ho Kim, Rae Woong Park, Ju‐Young Shin   +21 more
wiley   +1 more source

Alleviative effects of fluoxetine on depressive-like behaviors by epigenetic regulation of BDNF gene transcription in mouse model of post-stroke depression

Scientific Reports, 2017
Fluoxetine, one of the selective serotonin reuptake inhibitor (SSRI) antidepressants, has been thought to be effective for treating post-stroke depression (PSD).
Huijuan Jin, L. Pei, Ya‐nan Li, Hui Zheng, Shuai Yang, Yan-zhen Wan, L. Mao, Yuanpeng Xia, Quanwei He, Man Li, Zhen-yu Yue, Bo Hu   +11 more
semanticscholar   +1 more source

Sentience in cephalopod molluscs: an updated assessment

Biological Reviews, EarlyView.
ABSTRACT This article evaluates the evidence for sentience – the capacity to have feelings – in cephalopod molluscs: octopus, cuttlefish, squid, and nautilus. Our framework includes eight criteria, covering both whether the animal's nervous system could support sentience and whether their behaviour indicates sentience.
Alexandra K. Schnell, Heather Browning, Andrew Crump, Charlotte C. Burn, Jonathan Birch   +4 more
wiley   +1 more source