Control of Rhipicephalus microplus on taurine cattle with fluralaner in a subtropical region
Parasites & VectorsBackground In Rio Grande do Sul, Brazil, a region with a subtropical climate, Rhipicephalus microplus is present in taurine cattle raised for beef and milk. In addition, ticks resistant to multiple acaricides are present in this region.
Tiago Gallina +10 more
doaj +4 more sources
G3'MTMD3 in the insect GABA receptor subunit, RDL, confers resistance to broflanilide and fluralaner. [PDF]
PLoS Genetics, 2023 Meta-diamides (e.g. broflanilide) and isoxazolines (e.g. fluralaner) are novel insecticides that target the resistant to dieldrin (RDL) subunit of insect γ-aminobutyric acid receptors (GABARs).
Yichi Zhang +10 more
doaj +8 more sources
Mosquitocidal Activity and Mode of Action of the Isoxazoline Fluralaner [PDF]
International Journal of Environmental Research and Public Health, 2017 Mosquitoes, such as Aedes aegypti and Anopheles gambiae, are important vectors of human diseases. Fluralaner, a recently introduced parasiticide, was evaluated as a mosquitocide in this study. On Ae. aegypti and An. gambiae fourth-instar larvae, fluralaner had 24-h LC50 (lethal concentration for 50% mortality) values of 1.8 ppb and 0.4 ppb ...
Jiang, Shiyao +3 more
openaire +3 more sources
Safety of topical administration of fluralaner plus moxidectin concurrently with praziquantel in cats [PDF]
Parasites & Vectors, 2018 Background Fluralaner provides efficacy against feline ectoparasites following topical administration. Moxidectin is routinely used to treat gastrointestinal nematode infections and prevent heartworm disease caused by Dirofilaria immitis. Praziquantel is
Feli M. Walther +2 more
doaj +4 more sources
Plasma pharmacokinetic profile of fluralaner (Bravecto™) and ivermectin following concurrent administration to dogs [PDF]
Parasites & Vectors, 2015 Background Fluralaner is a novel systemic ectoparasiticide for dogs providing immediate and persistent flea, tick and mite control after a single oral dose.
Feli M. Walther +2 more
doaj +2 more sources
The effect of food on the pharmacokinetics of oral fluralaner in dogs [PDF]
Parasites & Vectors, 2014 Background Fluralaner is a novel systemic ectoparasiticide for dogs providing long-acting flea- and tick-control after a single oral dose. The pharmacokinetics of orally administered drugs may be influenced by feeding.
Feli M Walther +3 more
doaj +3 more sources
Efficacy of fluralaner against canine generalized demodicosis [PDF]
Brazilian Journal of Veterinary Medicine, 2019 Demodicosis is a parasitic dermatopathy, resulting from the excessive proliferation of Demodex mites. The rate at which this disease is encountered in the pet clinic is high, despite recent advances in the treatment of the disease. The aim of this study, which was conducted in Brazil, was to analyze the efficacy of fluralaner in the treatment of ...
Lopes, Natália Lôres +5 more
openaire +6 more sources
Topical, contact, and oral susceptibility of adult Culicoides biting midges (Diptera: Ceratopogonidae) to fluralaner [PDF]
Parasites & Vectors, 2023 Background Culicoides biting midges (Diptera: Ceratopogonidae) are economically important blood-feeding pests closely associated with livestock production. They are the principal vectors of two hemorrhagic disease viruses affecting both wild and domestic
Blythe E. Lawson, Emily G. McDermott
doaj +2 more sources
Theoretical and Experimental Study of Molecular Interactions of Fluralaner with Lipid Membranes
Journal of Agricultural and Food Chemistry, 2023 Fluralaner is a relatively new insecticide belonging to the isoxazoline group, whose action mechanism involves the blocking of GABAA-receptors in the insect nervous system. Because of its high hydrophobicity, fluralaner could bioaccumulate and reach toxic local concentrations.
María Salomé Gastaldi +4 more
openaire +4 more sources
Efficacy of fluralaner against Otodectes cynotis infestations in dogs and cats [PDF]
Parasites & Vectors, 2017 The efficacy of fluralaner for the treatment of Otodectes cynotis infestations in dogs and cats was evaluated after oral (dogs) or topical administration (dogs and cats). Twenty-four dogs and sixteen cats were experimentally infested with O. cynotis and randomly allocated to equal sized groups (n = 8/group).
Taenzler, Janina +4 more
openaire +4 more sources