Safety of concurrent treatment of dogs with fluralaner (Bravecto™) and milbemycin oxime - praziquantel [PDF]
Background Fluralaner (Bravecto™; Merck/MSD Animal Health) is a novel systemic ectoparasiticide for dogs providing long-acting flea and tick control after a single oral dose.
Feli M Walther +4 more
doaj +3 more sources
Flea and tick treatment satisfaction, preference, and adherence reported by cat owners in the U.S., U.K., or France who treated their cats with transdermal fluralaner [PDF]
Background: Fluralaner (Bravecto®) is an isoxazoline class compound that is the only topically applied systemic ectoparasiticide approved for dosing at up to 12-week intervals for flea and tick control in cats.
Robert Philip Lavan +4 more
doaj +1 more source
Flea and tick treatment satisfaction, preference, and adherence of U.S. cat owners prescribed topical fluralaner (Bravecto® Topical Solution for Cats) [PDF]
Background: Fluralaner is a novel isoxazoline compound and the only systemically distributed ectoparasiticide approved in the United States for re-dosing at up to 12-week intervals for flea and tick control in cats.
Robert Lavan +3 more
doaj +1 more source
Centripetal Axonal Transport as a Gateway to the CNS for Veterinary Antiparasitics: Bypassing the Blood-Brain Barrier, Clinical Impact in Vulnerable Age Groups, and the Potential Facilitating Role of PFAS. [PDF]
The widespread use of veterinary antiparasitics, including neonicotinoids, isoxazolines, avermectins, and pyrethroids, is essential for canine health but raises concerns regarding potential neurotoxicity, particularly in young and geriatric animals.
Britti D, Marabelli R, Calzetta L.
europepmc +2 more sources
Mosquitocidal Activity and Mode of Action of the Isoxazoline Fluralaner [PDF]
Mosquitoes, such as Aedes aegypti and Anopheles gambiae, are important vectors of human diseases. Fluralaner, a recently introduced parasiticide, was evaluated as a mosquitocide in this study. On Ae. aegypti and An. gambiae fourth-instar larvae, fluralaner had 24-h LC50 (lethal concentration for 50% mortality) values of 1.8 ppb and 0.4 ppb ...
Jiang, Shiyao +3 more
openaire +2 more sources
A comparison of the efficacy of selamectin and fluralaner in the treatment of the canaries infected with dermanyssus gallinae [PDF]
Dermanyssus gallinae is a hematophagous ectoparasite responsible for anaemia, weight loss, itching, dermatitis, and also decreased egg production in many domestic and wild bird species.
Çağatay ESİN +2 more
doaj +1 more source
Background Sarcoptic mange causes significant animal welfare and occasional conservation concerns for bare-nosed wombats (Vombatus ursinus) throughout their range.
Vicky Wilkinson +13 more
doaj +1 more source
Safety of concurrent treatment of cats with fluralaner and emodepsid–praziquantel [PDF]
Fluralaner is a novel systemic ectoparasiticide for cats providing immediate and persistent flea- and tick-control after a single topical dose. Emodepsid and praziquantel are routinely used to control intestinal worm infections in cats. The safety of concurrent use of fluralaner and a commercially available emodepsid-praziquantel combination topical ...
Walther, Feli M. +2 more
openaire +2 more sources
Functional Characterization of the Cat and Dog Wild-Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany. [PDF]
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Siegl L +6 more
europepmc +2 more sources
The Potential of Fluralaner as a Bait Toxicant to Control Pest Yellowjackets in California
The western yellowjacket, Vespula pensylvanica (Saussure), is an important seasonal pest of recreational and outdoor venues in the western United States. Its propensity to scavenge food increases the likelihood of stinging incidences. Control measures are limited to intensive trapping and treating subterranean nests.
Michael K. Rust +11 more
openaire +5 more sources

