Results 21 to 30 of about 1,337 (171)

Pharmacokinetics of fluralaner in dogs following a single oral or intravenous administration [PDF]

Parasites & Vectors, 2014
Background Fluralaner is a novel systemic insecticide and acaricide. The purpose of these studies was to investigate the pharmacokinetic properties of fluralaner in Beagle dogs following single oral or intravenous (i.v.) administration. Methods Following
Susanne Kilp, Diana Ramirez, Mark J Allan, Rainer KA Roepke, Martin C Nuernberger   +4 more
doaj   +3 more sources

Treatment of dogs with Bravecto® (fluralaner) reduces mosquito survival and fecundity

Parasites & Vectors, 2023
Background Mosquitoes serve as the vector of canine heartworm (Dirofilaria immitis), which represents a significant and persistent threat to canine health. A reduction in the longevity and/or reproductive success of mosquitoes that take a blood meal from
Christopher Charles Evans, Dorothy Normile, Sheryl Gamble, Frank Guerino, Michael T. Dzimianski, Andrew Riddell Moorhead   +5 more
doaj   +3 more sources

Fluralaner activity against life stages of ticks using Rhipicephalus sanguineus and Ornithodoros moubata IN in vitro contact and feeding assays [PDF]

Parasites & Vectors, 2015
Background Fluralaner is a novel isoxazoline eliciting both acaricidal and insecticidal activity through potent blockage of GABA- and glutamate-gated chloride channels.
Heike Williams, Hartmut Zoller, Rainer KA Roepke, Eva Zschiesche, Anja R Heckeroth   +4 more
doaj   +2 more sources

Efficacy of orally administered fluralaner in dogs against laboratory challenge with Haemaphysalis longicornis ticks

Parasites & Vectors, 2019
Background Haemaphysalis longicornis ticks represent an ectoparasitic health threat to dogs. This study evaluated the immediate and persistent efficacy of orally administered fluralaner for control of this tick.
Masanori Toyota, Kyoko Hirama, Tatsumi Suzuki, Rob Armstrong, Tatsuyuki Okinaga   +4 more
doaj   +2 more sources

Fluralaner treatment of chickens kills the southern house mosquito, Culex quinquefasciatus. [PDF]

Med Vet Entomol
Abstract The control of zoonotic and vector‐borne pathogens is challenging due to the limited availability of intervention tools. West Nile virus (WNV) is an example of a globally distributed zoonotic arbovirus that circulates between Culex species (Diptera: Culicidae ...
Knape K, Tian Y, Durden C, Adams DR, Garza M, Carey JB, Hamer SA, Hamer GL.   +7 more
europepmc   +4 more sources

Fecal elimination of fluralaner in different carnivore species after oral administration [PDF]

Frontiers in Veterinary Science
Fluralaner is a recent external parasiticide, first of a new class of drugs (isoxazoline parasiticides). It is widely used in companion animals both for its wide spectrum (fleas, ticks and other mites) but also for its ease of use (oral tablets given once for 1 to three months).
Berny PJ, Belhadj D, España B, Lécu A.
exaly   +5 more sources

SPECTROFLUORIMETRIC DETERMINATION AND OPTIMIZATION OF FLURALANER IN PHARMACEUTICAL FORMULATIONS [PDF]

Al-Azhar Journal of Pharmaceutical Sciences
A sensitive and accurate native spectrofluorimetric method was developed and validated for the quantification of Fluralaner in pharmaceutical formulations.
Yaser Reda, Ahmed Mohamed, Mohamed Hasan, Omneya El-Naggar   +3 more
doaj   +2 more sources

Onset of activity of fluralaner (BRAVECTO™) against Ctenocephalides felis on dogs [PDF]

Parasites & Vectors, 2014
Background Fluralaner (Bravecto™) is a novel systemic insecticide and acaricide that provides long persistent antiparasitic activity following a single administration at the minimum dose of 25 mg/kg body weight.
Janina Taenzler, Christina Wengenmayer, Heike Williams, Josephus Fourie, Eva Zschiesche, Rainer KA Roepke, Anja R Heckeroth   +6 more
doaj   +3 more sources

Clinical efficacy and safety of a single administration of fluralaner injectable suspension (BRAVECTO® injectable) vs. monthly administration of oral afoxolaner (NexGard®) in dogs for tick and flea control over one year under European field conditions [PDF]

Parasites & Vectors
Background Year-round control of canine flea and tick infestations requires owner compliance with recommendations for regular treatments. Compliance failures can result in increased exposure of dogs to tick-borne pathogens and resurgence of flea ...
Ivo Petersen, Susanne Goebel-Lauth, Thierry Pobel, Maria J. Gil, Wolfgang Löhlein, Oliver Wolf, Eva Zschiesche, Bjoern Welzel, Lea Heinau   +8 more
doaj   +2 more sources

Flea and tick treatment satisfaction, preference, and adherence reported by cat owners in the U.S., U.K., or France who treated their cats with transdermal fluralaner [PDF]

Open Veterinary Journal, 2021
Background: Fluralaner (Bravecto®) is an isoxazoline class compound that is the only topically applied systemic ectoparasiticide approved for dosing at up to 12-week intervals for flea and tick control in cats.
Robert Philip Lavan, Rob Armstrong, Hannah Newbury, Dorothy Normile, Celine Hubinois   +4 more
doaj   +1 more source