Results 61 to 70 of about 33,112 (265)
Investigating the suitability of high content image analysis as a tool to assess the reversibility of foamy alveolar macrophage phenotypes in vitro. [PDF]
, 2020 Many potential inhaled medicines fail during development due to the induction of a highly vacuolated or “foamy” alveolar macrophage phenotype response in pre-clinical studies.
Hoffman, Ewelina +2 more
core +2 more sources
PM&R, EarlyView.Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen +7 more
wiley +1 more source
Anti-leukotriene compared to inhaled corticosteroid for recurrent wheezing in children under five years of age: A randomized clinical trial [PDF]
Journal of Research in Clinical MedicineIntroduction: Asthma is the common chronic disease in childhood. One of the major symptoms of asthma in children is wheezing. According to the international guidelines, inhaled corticosteroid (ICS) is prescribed for treating recurrent wheezing in ...
Mahnaz Sadeghi-Shabestari +3 more
doaj +1 more source
Respirology, EarlyView.ABSTRACT Chronic obstructive pulmonary disease (COPD) remains the third leading cause of death worldwide, and conventional bronchodilator‐based therapies have limited efficacy in preventing exacerbations and disease progression. The 2024–2026 period represents a historic inflection point: three mechanistically distinct agents received Food and Drug ...
Naoya Fujino, Hisatoshi Sugiura
wiley +1 more source
Validation of the Human Ozone Challenge Model as a Tool for Assessing Anti-Inflammatory Drugs in Early Development [PDF]
, 2005 This study aimed to test the utility of the ozone challenge model for profiling novel compounds designed to reduce airway inflammation. The authors used a randomized, doubledummy, double-blind, placebo-controlled 3-period crossover design alternating ...
Gibson, Anthony +9 more
core +1 more source
Allergy, EarlyView.Adipokine secretion from adipose tissue may be involved in obesity‐related asthma, but it is unknown how adipokine levels relate to asthma characteristics. Plasma adipokines were measured in well‐characterized lean, overweight or obese patients with mild‐to‐moderate or severe asthma.
Lars I. Andersson +20 more
wiley +1 more source
Availability and Costs of Allergic Rhinitis Treatments Across the World: A Survey of ARIA Experts
Allergy, EarlyView.We surveyed experts of the ARIA group on the costs of medications for allergic rhinitis in the respective countries. Overall, oral antihistamines are the cheapest medications while fixed combinations of antihistamines + corticosteroids are the most expensive.
Maria Clara Urbano +75 more
wiley +1 more source
International Journal of COPD, 2020 Ji-Ho Lee,1,* You Hyun Park,2,* Dae Ryong Kang,3 Seok Jeong Lee,1 Myoung Kyu Lee,1 Sang-Ha Kim,1 Suk Joong Yong,1 Won-Yeon Lee1 1Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea; 2Department of Biostatistics ...
Lee JH +7 more
doaj
The clinical effectiveness and cost-effectiveness of inhaler devices used in the routine management of chronic asthma in older children: a systematic review and economic evaluation [PDF]
, 2002 Background: This review examines the clinical effectiveness and cost-effectiveness of hand-held inhalers to deliver medication for the routine management of chronic asthma in children aged between 5 and 15 years.
Beverley, C. +4 more
core +1 more source
Allergy, EarlyView.ABSTRACT Background To achieve adequate symptom control, patients with allergic rhinitis (AR) often need to increase their medication dose or add other treatments (co‐medication). We aimed to perform a systematic review to compare the efficacy and safety of AR medications for increased dose versus co‐medication.
Bernardo Sousa‐Pinto +44 more
wiley +1 more source