Results 51 to 60 of about 18,308 (279)

Recovery of viral RNA and infectious foot-and-mouth disease virus from positive lateral-flow devices [PDF]

open access: yes, 2014
Foot-and-mouth disease Virus (FMDV) is an economically important, highly contagious picornavirus that affects both wild and domesticated cloven hooved animals. In developing countries, the effective laboratory diagnosis of foot-and-mouth disease (FMD) is
Armson, Bryony   +10 more
core   +2 more sources

A gold nanoparticle strip for simultaneously evaluating FMDV immunized antibody level and discriminating FMDV vaccinated animals from infected animals

open access: goldRSC Advances, 2019
A gold nanoparticle strip was developed for rapidly evaluating FMDV type O antibody level and simultaneously discriminating FMDV vaccinated animals from infected animals.
Suzhen Yang   +5 more
openalex   +5 more sources

The High Immunity Induced by the Virus-Like Particles of Foot-and-Mouth Disease Virus Serotype O

open access: yesFrontiers in Veterinary Science, 2021
Foot-and-mouth disease (FMD), caused by FMD virus (FMDV), is a highly contagious and economically devastating viral disease of cloven-hoofed animals worldwide.
Yan Xiao   +13 more
doaj   +1 more source

Failure of vaccination to prevent outbreaks of foot-and-mouth disease [PDF]

open access: yes, 1996
Outbreaks of foot-and-mouth disease persist in dairy cattle herds in Saudi Arabia despite revaccination at intervals of 4-6 months. Vaccine trials provide data on antibody responses following vaccination.
A. Pearson   +12 more
core   +2 more sources

The Application of the Gibson Assembly Method in the Production of Two pKLS3 Vector-Derived Infectious Clones of Foot-and-Mouth Disease Virus

open access: yesVaccines, 2023
The construction of a full-length infectious clone, essential for molecular virological study and vaccine development, is quite a challenge for viruses with long genomes or possessing complex nucleotide sequence structures.
Ploypailin Semkum   +5 more
doaj   +1 more source

Viral Genome Segmentation Can Result from a Trade-Off between Genetic Content and Particle Stability [PDF]

open access: yes, 2011
The evolutionary benefit of viral genome segmentation is a classical, yet unsolved question in evolutionary biology and RNA genetics. Theoretical studies anticipated that replication of shorter RNA segments could provide a replicative advantage over ...
Arias, Armando   +7 more
core   +3 more sources

An anti-picornaviral strategy based on the crystal structure of foot-and-mouth disease virus 2C protein

open access: yesCell Reports, 2022
Summary: The foot-and-mouth disease virus (FMDV) 2C protein shares conserved motifs with enterovirus 2Cs despite low sequence identity. Here, we determine the crystal structure of an FMDV 2C fragment to 1.83 Å resolution, which comprises an ATPase domain,
Chu Zhang   +10 more
doaj  

Foot-and-Mouth Disease Virus 3C Protease Antagonizes Interferon Signaling and C142T Substitution Attenuates the FMD Virus

open access: yesFrontiers in Microbiology, 2021
3C protease (3Cpro), a chymotrypsin-like cysteine protease encoded by the foot-and-mouth disease virus (FMDV), plays an essential role in processing the FMDV P1 polyprotein into individual viral capsid proteins in FMDV replication.
Pathum Ekanayaka   +10 more
doaj   +1 more source

Differentiation of Foot-and-Mouth Disease-Infected pigs from Vaccinated Pigs Using Antibody-Detecting Sandwich ELISA [PDF]

open access: yes, 2011
The presence of serum antibodies for nonstructural proteins of the foot-and-mouth disease virus (FMDV) can differentiate FMDV-infected animals from vaccinated animals.
Aldo DEKKER   +10 more
core   +3 more sources

Sec62 Regulates Endoplasmic Reticulum Stress and Autophagy Balance to Affect Foot-and-Mouth Disease Virus Replication

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Endoplasmic reticulum (ER) stress-induced autophagy is closely associated with viral infection and propagation. However, the intrinsic link between ER stress, autophagy, and viral replication during foot-and-mouth disease virus (FMDV) infection is not ...
Jin’en Wu   +6 more
doaj   +1 more source

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