Results 1 to 10 of about 17,009 (134)

Sulfur compounds navigate redox processes, leukotriene synthesis, and ω-hydroxylation of leukotriene B4 in neutrophil interaction with the bacteria Salmonella typhimurium: the way to manipulate neutrophil swarming [PDF]

Frontiers in Immunology
Neutrophils are the first immune cells recruited by invading pathogens. During interaction with bacteria, neutrophils synthesize leukotriene B4, a potent chemoattractant that, in conjunction with the primary bacterial chemoattractant N-formyl-l-methionyl-
Ekaterina A. Golenkina, Sofia V. Navarnova, Galina M. Viryasova, Svetlana I. Galkina, Tatjana V. Gaponova, Yulia M. Romanova, Galina F. Sud’ina   +6 more
doaj   +2 more sources

Altered Ca²⁺ homeostasis in polymorphonuclear leukocytes from chronic myeloid leukaemia patients [PDF]

Molecular Cancer, 2006
Background In polymorphonuclear leukocytes (PMNL), mobilization of calcium ions is one of the early events triggered by binding of chemoattractant to its receptors.
Revankar Chetana M, Advani Suresh H, Naik Nishigandha R   +2 more
doaj   +2 more sources

Dapsone Alters Phenotypical and Functional Properties of Human Neutrophils In Vitro [PDF]

Molecules
Dapsone is a sulfone used in treating inflammatory skin conditions. Despite its widespread dermatological use, the pharmacological actions of dapsone remain poorly understood.
Sara Rakočević, Vanja Mališ, Ljiljana Kozić, Anđela Dubovina, Marija Drakul, Dejan Bokonjić, Miodrag Čolić, Dušan Mihajlović   +7 more
doaj   +2 more sources

Phenotype remodeling in neutrophilic granulocyte subsets CD64^-CD32⁺CD16⁺CD11B⁺NG, CD64⁺CD32⁺CD16⁺CD11B⁺NG in de novo experimental model of viral-bacterial infection in vitro

Инфекция и иммунитет, 2021
A search for new targeted therapeutic strategies based on examining immunopathogenetic mechanisms for emerging co-infections is relevant and may further contribute not only to optimizing choice of immunotropic drugs, but also to achieving positive ...
I. V. Nesterova, G. A. Chudilova, T. V. Rusinova, V. N. Pavlenko, Ya. A. Yutskevich, N. K. Barova, V. A. Tarakanov   +6 more
doaj   +1 more source

Exhaustive Exercise Increases Spontaneous but Not fMLP-Induced Production of Reactive Oxygen Species by Circulating Phagocytes in Amateur Sportsmen

Biology, 2022
Strenuous exercise alters the oxidative response of blood phagocytes to various agonists. However, little is known about spontaneous post exercise oxidant production by these cells.
Adam Chmielecki, Krzysztof Bortnik, Szymon Galczynski, Gianluca Padula, Hanna Jerczynska, Robert Stawski, Dariusz Nowak   +6 more
doaj   +1 more source

Effects of Feeding Fermented Mulberry Leaf Powder on Growth Performance, Slaughter Performance, and Meat Quality in Chicken Broilers

Animals, 2021
This study was conducted to investigate the effects of feeding fermented mulberry leaf powder (FMLP) on growth performance, slaughter performance, and meat quality of broilers. A total of 360 1-day-old chickens were randomly divided into 5 groups.
Yanan Ding, Xiaodie Jiang, Xiaofeng Yao, Haihan Zhang, Zehe Song, Xi He, Rong Cao   +6 more
doaj   +1 more source

Serum of limb remote ischemic postconditioning inhibits fMLP-triggered activation and reactive oxygen species releasing of rat neutrophils

Redox Report, 2021
Objectives The study explores the protective role of the peripheral serum of limb remote ischemic postconditioning (LRIP) in reducing the reactive oxygen species (ROS) levels and neutrophil activation, which are responsible for the deleterious ...
Gangling Chen, Jiangwei Zhang, Mingyue Sheng, Sanli Zhang, Qi Wu, Lei Liu, Boyang Yu, Junping Kou   +7 more
doaj   +1 more source

LRRK2 is involved in the chemotaxis of neutrophils and differentiated HL-60 cells, and the inhibition of LRRK2 kinase activity increases fMLP-induced chemotactic activity

Cell Communication and Signaling, 2023
Background Neutrophils depend heavily on glycolysis for energy production under normal conditions. In contrast, neutrophils require energy supplied by mitochondrial oxidative phosphorylation (OXPHOS) during chemotaxis. However, the mechanism by which the
Yuichi Mazaki, Haruka Handa, Yoshizuki Fumoto, Takahiro Horinouchi, Yasuhito Onodera   +4 more
doaj   +1 more source

Novel nano-carriers with N-formylmethionyl-leucyl-phenylalanine-modified liposomes improve effects of C16-angiopoietin 1 in acute animal model of multiple sclerosis

Drug Delivery, 2023
Gradual loss of neuronal structure and function due to impaired blood–brain barrier (BBB) and neuroinflammation are important factors in multiple sclerosis (MS) progression. Our previous studies demonstrated that the C16 peptide and angiopoietin 1 (Ang-1)
Xiao-Xiao Fu, Han Qu, Jing Wang, Hua-Ying Cai, Hong Jiang, Hao-Hao Chen, Shu Han   +6 more
doaj   +1 more source

Increased migration of monocytes in essential hypertension is associated with increased transient receptor potential channel canonical type 3 channels. [PDF]

PLoS ONE, 2012
Increased transient receptor potential canonical type 3 (TRPC3) channels have been observed in patients with essential hypertension. In the present study we tested the hypothesis that increased monocyte migration is associated with increased TRPC3 ...
Zhigang Zhao, Yinxing Ni, Jing Chen, Jian Zhong, Hao Yu, Xingsen Xu, Hongbo He, Zhencheng Yan, Alexandra Scholze, Daoyan Liu, Zhiming Zhu, Martin Tepel   +11 more
doaj   +1 more source