Results 1 to 10 of about 56,684 (297)
Allergology International, 2023 Chronic spontaneous urticaria (CSU) is a common skin disease without an etiology in the vast majority of cases. The similarity of symptoms and pathology to allergen-induced skin reactions supports that skin mast cell IgE receptor activation is also ...
Sarbjit S. Saini
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Nature Communications, 2023 Basophils are the rarest granulocytes and are recognized as critical cells for type 2 immune responses. However, their differentiation pathway remains to be fully elucidated.
Kenji Ishiwata +2 more
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Is There a Role for Basophils in Cancer?
Frontiers in Immunology, 2020 Basophils were identified in human peripheral blood by Paul Ehrlich over 140 years ago. Human basophils represent <1% of peripheral blood leukocytes.
Giancarlo Marone +18 more
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Basophils in antihelminth immunity
Seminars in Immunology, 2021 It has been appreciated that basophilia is a common feature of helminth infections for approximately 50 years. The ability of basophils to secrete IL-4 and other type 2 cytokines has supported the prevailing notion that basophils contribute to antihelminth immunity by promoting optimal type 2 T helper (Th2) cell responses.
Jianya Peng
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Systemic immunologic effects of long-term dupilumab treatment in severe eosinophilic asthma beyond clinical outcomes [PDF]
Frontiers in AllergyIntroductionDupilumab, an IL-4Rα antagonist that blocks IL-4/IL-13 signalling, is used in severe eosinophilic asthma to improve clinical control and suppress type 2 inflammation.MethodsWe evaluated the clinical and systemic immunologic effects of ...
Sabina Škrgat +11 more
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Allergology International, 2021 Background: Although basophils are considered to play an important role for maintenance of type 2 inflammation in atopic dermatitis (AD), studies on basophils in AD patients are limited.
Shinya Imamura +5 more
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The Basophilic Granulocyte [PDF]
Blood, 1959 Abstract 1. The history, morphology and technics of counting of basophils have been briefly reviewed. 2. A marked relative and absolute increase of basophils was always found in chronic myelogenous leukemia. Moderate relative and absolute increases of basophils usually occurred in myeloid metaplasias (including ...
R E, FREDRICKS, W C, MOLONEY
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IgE Autoreactivity in Atopic Dermatitis: Paving the Road for Autoimmune Diseases?
Antibodies, 2020 Atopic dermatitis (AD) is a common skin disease affecting 20% of the population beginning usually before one year of age. It is associated with the emergence of allergen-specific IgE, but also with autoreactive IgE, whose function remain elusive.
Christophe Pellefigues
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The roles of basophils in mediating the immune responses
European Journal of Inflammation, 2021 Basophils are the rarest blood cell population and have not been extensively studied. Our understanding of the functions of basophils is limited to their roles as the main effector cells in hypersensitivity reactions.
Na Zhang, Ze-Ming Zhang, Xiao-Fei Wang
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Basophils as a potential marker of lupus nephritis by flow cytometry
Future Science OA, 2021 Objective: To establish a convenient and simple flow cytometry immunophenotyping panel to explore immune cellular alterations and potential cellular biomarkers in systemic lupus erythematosus.
Yanni Jiang +5 more
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