Results 11 to 20 of about 53,289 (299)
Allergology International, 2023 Chronic spontaneous urticaria (CSU) is a common skin disease without an etiology in the vast majority of cases. The similarity of symptoms and pathology to allergen-induced skin reactions supports that skin mast cell IgE receptor activation is also ...
Sarbjit S. Saini
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Basophils Orchestrating Eosinophils’ Chemotaxis and Function in Allergic Inflammation [PDF]
Cells, 2021 Eosinophils are well known to contribute significantly to Th2 immunity, such as allergic inflammations. Although basophils have often not been considered in the pathogenicity of allergic dermatitis and asthma, their role in Th2 immunity has become ...
Joseena Iype, Michaela Fux
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Basophils from allergy to cancer
Frontiers in Immunology, 2022 Human basophils, first identified over 140 years ago, account for just 0.5-1% of circulating leukocytes. While this scarcity long hampered basophil studies, innovations during the past 30 years, beginning with their isolation and more recently in the ...
Remo Poto +15 more
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CD25 as a unique marker on human basophils in stable-mildly symptomatic allergic asthma [PDF]
Frontiers in Immunology, 2023 BackgroundBasophils in acute asthma exacerbation are activated as evidenced by their increased expression levels of activation markers such as CD203c and CD63.
Joseena Iype +7 more
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Basophils beyond allergic and parasitic diseases
Frontiers in Immunology, 2023 Basophils bind IgE via FcεRI-αβγ2, which they uniquely share only with mast cells. In doing so, they can rapidly release mediators that are hallmark of allergic disease.
Remo Poto +18 more
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Selective depletion of basophils ameliorates immunoglobulin E-mediated anaphylaxis [PDF]
Biochemistry and Biophysics Reports, 2017 Basophils, which are the rarest granulocytes, play crucial roles in protective immunity against parasites and development of allergic disorders. Although immunoglobulin (Ig)E-dependent responses via receptor for IgE (FcεRI) in basophils have been ...
Takeshi Nakamura +6 more
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Emerging roles of basophils in allergic inflammation
Allergology International, 2017 Basophils have long been neglected in immunological studies because they were regarded as only minor relatives of mast cells. However, recent advances in analytical tools for basophils have clarified the non-redundant roles of basophils in allergic ...
Kensuke Miyake, Hajime Karasuyama
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Journal of Clinical Investigation, 1980 Factors influencing basophil production from the bone marrow of ovalbumin (OA)-sensitized guinea pigs have been examined in vitro. Autologous co-cultures of marrow and spleen cells from OA-immune animals contained significantly higher numbers of basophils after 7 d of liquid culture in the presence of OA, compared with control co-cultures or with ...
J A, Denburg, M, Davison, J, Bienenstock
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Immunity, 2008 In this issue of Immunity, Tsujimura et al. (2008) report that the release of platelet-activating factor by basophils stimulated with immunoglobulin G1 (IgG1)-antigen immune complexes contributes substantially to the expression of an IgG1-dependent alternative pathway of systemic anaphylaxis in mice.
Galli, Stephen J. +1 more
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The Basophilic Granulocyte [PDF]
Blood, 1959 Abstract 1. The history, morphology and technics of counting of basophils have been briefly reviewed. 2. A marked relative and absolute increase of basophils was always found in chronic myelogenous leukemia. Moderate relative and absolute increases of basophils usually occurred in myeloid metaplasias (including ...
R E, FREDRICKS, W C, MOLONEY
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