Results 31 to 40 of about 56,684 (297)
Immunity & Ageing, 2018 Background The influence of age on basophils is poorly understood, as well as the effect of aging-associated microbiota on basophils. Therefore, we studied the influence of aging and aging-associated microbiota on basophil frequency and phenotype, and ...
Adriaan A. van Beek +5 more
doaj +1 more source
New Insights into the Roles for Basophils in Acute and Chronic Allergy
Allergology International, 2009 Basophils represent less than 1% of peripheral blood leukocytes. They are often recruited to the site of allergic inflammation, albeit in small numbers.
Kaori Mukai +3 more
doaj +1 more source
好塩基球からのヒスタミン遊離に関する研究. 1 自動分析装置による全血からのヒスタミン遊離の測定 [PDF]
, 1983 Histamine released from whole blood was determined by an automated fiuorometric histamine analysis system. The increased release of histamine from basophils by anti-IgE was observed in ten healthy subjects and 12 extrinsic asthma patients, while the ...
Tanizaki, Yoshiro +9 more
core +1 more source
Basophils and Skin Disorders [PDF]
, 2014 Since their discovery in 1879, basophils have been viewed as circulating blood granulocytes with limited immune function. New research tools for their functional analysis in vivo have revealed previously unrecognized roles for basophils in several skin ...
BORRIELLO, FRANCESCO +2 more
core +2 more sources
Clinical and Translational Allergy, 2022 Background IgE and high‐affinity IgE receptor (FcεRI) expression on basophils have been scarcely explored in patients with chronic inducible urticaria (CIndU).
Ana M. Giménez‐Arnau +5 more
doaj +1 more source
The Basoph8 Mice Enable an Unbiased Detection and a Conditional Depletion of Basophils
Frontiers in Immunology, 2019 Basophils are granulocytes involved in parasite immunity and allergic diseases, known for their potent secretion of type 2 cytokines. Identifying their functions has proven to be controversial due to their relative rarity and their complex lineage ...
Christophe Pellefigues +9 more
doaj +1 more source
SARS-CoV-2 Induces Cytokine Responses in Human Basophils
Frontiers in Immunology, 2022 Basophils play a key role in the orientation of immune responses. Though the interaction of SARS-CoV-2 with various immune cells has been relatively well studied, the response of basophils to this pandemic virus is not characterized yet.
Srinivasa Reddy Bonam +8 more
doaj +1 more source
UDP/P2Y6 receptor signaling regulates IgE-dependent degranulation in human basophils
Allergology International, 2017 Background: P2Y purinergic receptors (P2YR) are G protein-coupled receptors that are stimulated by extracellular nucleotides. They mediate cellular effects by regulating cAMP production, protein kinase C activation, inositol trisphosphate generation, and
Manabu Nakano +7 more
doaj +1 more source
Biomarkers for Allergen Immunotherapy in Cedar Pollinosis
Allergology International, 2009 To initiate, monitor, and complete effective immunotherapy, biomarkers to predict and visualize the immune responses are needed. First, we need to identify the right candidate for immunotherapy.
Takao Fujisawa +9 more
doaj +1 more source
Effect of brimonidine tartrate on basophil activation in glaucoma patients
International Journal of Ophthalmology, 2020 AIM: To evaluate the mechanism of which brimonidine tartrate 0.15% causes clinical hypersensitivity. METHODS: A prospective case-control study comparing 8 glaucoma patients with clinical hypersensitivity to brimonidine to a control group consisting 13 ...
Eldar Rosenfeld +7 more
doaj +1 more source