Results 31 to 40 of about 53,289 (299)

IL-1β promotes immunoregulatory responses in human blood basophils.

open access: yes, 2021
Human basophils are essential effector cells of chronic allergic inflammation. IL-1 family cytokines such as interleukin (IL)-33 and IL-1β are elevated in serum and bronchoalveolar lavage fluid of allergic asthmatics.
Fux, Michaela   +9 more
core   +1 more source

IgE and high‐affinity IgE receptor in chronic inducible urticaria, pathogenic, and management relevance

open access: yesClinical and Translational Allergy, 2022
Background IgE and high‐affinity IgE receptor (FcεRI) expression on basophils have been scarcely explored in patients with chronic inducible urticaria (CIndU).
Ana M. Giménez‐Arnau   +5 more
doaj   +1 more source

SARS-CoV-2 Induces Cytokine Responses in Human Basophils

open access: yesFrontiers in Immunology, 2022
Basophils play a key role in the orientation of immune responses. Though the interaction of SARS-CoV-2 with various immune cells has been relatively well studied, the response of basophils to this pandemic virus is not characterized yet.
Srinivasa Reddy Bonam   +8 more
doaj   +1 more source

The Basoph8 Mice Enable an Unbiased Detection and a Conditional Depletion of Basophils

open access: yesFrontiers in Immunology, 2019
Basophils are granulocytes involved in parasite immunity and allergic diseases, known for their potent secretion of type 2 cytokines. Identifying their functions has proven to be controversial due to their relative rarity and their complex lineage ...
Christophe Pellefigues   +9 more
doaj   +1 more source

Biomarkers for Allergen Immunotherapy in Cedar Pollinosis

open access: yesAllergology International, 2009
To initiate, monitor, and complete effective immunotherapy, biomarkers to predict and visualize the immune responses are needed. First, we need to identify the right candidate for immunotherapy.
Takao Fujisawa   +9 more
doaj   +1 more source

Effect of brimonidine tartrate on basophil activation in glaucoma patients

open access: yesInternational Journal of Ophthalmology, 2020
AIM: To evaluate the mechanism of which brimonidine tartrate 0.15% causes clinical hypersensitivity. METHODS: A prospective case-control study comparing 8 glaucoma patients with clinical hypersensitivity to brimonidine to a control group consisting 13 ...
Eldar Rosenfeld   +7 more
doaj   +1 more source

Interactions between Innate Lymphoid Cells and Cells of the Innate and Adaptive Immune System

open access: yesFrontiers in Immunology, 2017
Type 2 innate lymphoid cells (ILC2s) are a major source of cytokines, which are also produced by Th2 cells and several cell types of the innate immune system.
Cornelia Symowski, David Voehringer
doaj   +1 more source

THE HEMIC BASOPHIL [PDF]

open access: yesJournal of Experimental Medicine, 1920
1. The basophilic granule of blood and marrow cells does not show the brown color reaction with benzidine solutions that is characteristic of the neutrophilic and eosinophilic granules. It differs from these types also in other important microchemical and physical particulars. 2.
openaire   +2 more sources

MHC class II expression in human basophils: induction and lack of functional significance. [PDF]

open access: yesPLoS ONE, 2013
The antigen-presenting abilities of basophils and their role in initiating a Th2 phenotype is a topic of current controversy. We aimed to determine whether human basophils can be induced to express MHC Class II and act as antigen presenting cells for T ...
Astrid L Voskamp   +4 more
doaj   +1 more source

Role of Basophils in a Broad Spectrum of Disorders

open access: yesFrontiers in Immunology, 2022
Basophils are the rarest granulocytes and have long been overlooked in immunological research due to their rarity and similarities with tissue-resident mast cells.
Kensuke Miyake   +2 more
doaj   +1 more source

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