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Basophil Production [PDF]

open access: yesJournal of Clinical Investigation, 1980
Factors influencing basophil production from the bone marrow of ovalbumin (OA)-sensitized guinea pigs have been examined in vitro. Autologous co-cultures of marrow and spleen cells from OA-immune animals contained significantly higher numbers of basophils after 7 d of liquid culture in the presence of OA, compared with control co-cultures or with ...
J A, Denburg, M, Davison, J, Bienenstock
openaire   +2 more sources

Basophils Are Back! [PDF]

open access: yesImmunity, 2008
In this issue of Immunity, Tsujimura et al. (2008) report that the release of platelet-activating factor by basophils stimulated with immunoglobulin G1 (IgG1)-antigen immune complexes contributes substantially to the expression of an IgG1-dependent alternative pathway of systemic anaphylaxis in mice.
Galli, Stephen J.   +1 more
openaire   +2 more sources

The Basophilic Granulocyte [PDF]

open access: yesBlood, 1959
Abstract 1. The history, morphology and technics of counting of basophils have been briefly reviewed. 2. A marked relative and absolute increase of basophils was always found in chronic myelogenous leukemia. Moderate relative and absolute increases of basophils usually occurred in myeloid metaplasias (including ...
R E, FREDRICKS, W C, MOLONEY
openaire   +2 more sources

When is a mouse basophil not a basophil?

open access: yesBlood, 2006
AbstractThe identification and characterization of mouse basophils have historically been hampered by the extreme rarity of this cell type. Virtually no photomicrographs of hematologically stained (eg, Wright-Giemsa) examples of mouse basophils exist in the literature. However, 4 recent studies in the past 2 years have used flow cytometry and a defined
James J, Lee, Michael P, McGarry
openaire   +3 more sources

Urticaria and basophils

open access: yesAllergology International, 2023
Chronic spontaneous urticaria (CSU) is a common skin disease without an etiology in the vast majority of cases. The similarity of symptoms and pathology to allergen-induced skin reactions supports that skin mast cell IgE receptor activation is also involved in CSU.
openaire   +3 more sources

THE HEMIC BASOPHIL [PDF]

open access: yesJournal of Experimental Medicine, 1920
1. The basophilic granule of blood and marrow cells does not show the brown color reaction with benzidine solutions that is characteristic of the neutrophilic and eosinophilic granules. It differs from these types also in other important microchemical and physical particulars. 2.
openaire   +2 more sources

Adventures with the Basophil

open access: yesJournal of Investigative Dermatology, 1962
For many, the word adventure conjures travel to distant lands or the exploration of endless outer space. I hope this afternoon to show you that adventure still exists no further away than your fingertips. This is a chronicle of the adventures we have had with a “cinderella” cell in a drop of blood.
openaire   +2 more sources

Isolation of Human Basophils [PDF]

open access: yesCurrent Protocols in Immunology, 2016
AbstractIsolating human basophils from blood has long been hampered by the fact that these granulocytes represent just 1% or less of the circulating leukocyte population. We describe herein laboratory protocols that have been refined over the past ∼25 years that now enable investigators to prepare basophils for use in a variety of assays to assess the ...
John T, Schroeder, Anja P, Bieneman
openaire   +2 more sources

No Mitoses in Basophilic Erythroblasts

open access: yesExperimental Biology and Medicine, 1974
SummaryIn the rabbit, under conditions in which mitoses accumulated in the acidophilic erythroblasts, none were observed in the basophilic erythroblasts. On the basis of certain assumptions, the basophilic erythroblasts were divided into two size classes: of average long diameters (as measured here) 10.3 and 8.4 nm.
H, Borsook, S, Jiggins
openaire   +2 more sources

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