Results 11 to 20 of about 108,915 (302)

New insights into basophil heterogeneity. [PDF]

open access: yes, 2016
Basophils have become increasingly recognized as important innate immune cells that mediate antihelminth immunity and barrier inflammation. Recent discoveries have uncovered previously unrecognized heterogeneity in basophil populations.
Kim, BS   +5 more
core   +3 more sources

Basophil Production [PDF]

open access: yesJournal of Clinical Investigation, 1980
Factors influencing basophil production from the bone marrow of ovalbumin (OA)-sensitized guinea pigs have been examined in vitro. Autologous co-cultures of marrow and spleen cells from OA-immune animals contained significantly higher numbers of basophils after 7 d of liquid culture in the presence of OA, compared with control co-cultures or with ...
J A, Denburg, M, Davison, J, Bienenstock
openaire   +2 more sources

Plasmacytoid dendritic cells diminution in peripheral blood is prevalent in drug reaction with eosinophilia and systemic symptoms and may precede human herpesvirus 6 reactivation

open access: yesDermatologica Sinica, 2021
Background: Plasmacytoid dendritic cells (pDCs) are implicated in the reactivation of human herpesvirus 6 (HHV-6) in drug reaction with eosinophilia and systemic symptoms (DRESS).
Shao-Hsuan Hsu   +6 more
doaj   +1 more source

Urticaria and basophils

open access: yesAllergology International, 2023
Chronic spontaneous urticaria (CSU) is a common skin disease without an etiology in the vast majority of cases. The similarity of symptoms and pathology to allergen-induced skin reactions supports that skin mast cell IgE receptor activation is also involved in CSU.
openaire   +3 more sources

Basophils Are Back! [PDF]

open access: yesImmunity, 2008
In this issue of Immunity, Tsujimura et al. (2008) report that the release of platelet-activating factor by basophils stimulated with immunoglobulin G1 (IgG1)-antigen immune complexes contributes substantially to the expression of an IgG1-dependent alternative pathway of systemic anaphylaxis in mice.
Galli, Stephen J.   +1 more
openaire   +2 more sources

Immune-Mediated Mechanisms in Cofactor-Dependent Food Allergy and Anaphylaxis: Effect of Cofactors in Basophils and Mast Cells

open access: yesFrontiers in Immunology, 2021
Cofactors may explain why in some cases food ingestion leads to anaphylaxis while in others elicits a milder reaction or tolerance. With cofactors, reactions become more severe and/or have a lower allergen threshold. Cofactors are present in up to 58% of
Rosa Muñoz-Cano   +31 more
doaj   +1 more source

Is There a Role for Basophils in Cancer?

open access: yesFrontiers in Immunology, 2020
Basophils were identified in human peripheral blood by Paul Ehrlich over 140 years ago. Human basophils represent <1% of peripheral blood leukocytes.
Giancarlo Marone   +18 more
doaj   +1 more source

Immune Clues to Sinus Blues: Linking Biomarkers to Radiologic Score of Rhinosinusitis. [PDF]

open access: yesWorld J Otorhinolaryngol Head Neck Surg
ABSTRACT Background Chronic rhinosinusitis (CRS) is a prolonged inflammatory condition of the nasal and paranasal sinuses that significantly affects quality of life. This study examines the relationship between CRS severity (based on Lund‐Mackay [LM] scores), osteitis, and systemic inflammatory markers, including neutrophil‐to‐lymphocyte ratio (NLR ...
Khreesha L   +10 more
europepmc   +2 more sources

When is a mouse basophil not a basophil?

open access: yesBlood, 2006
AbstractThe identification and characterization of mouse basophils have historically been hampered by the extreme rarity of this cell type. Virtually no photomicrographs of hematologically stained (eg, Wright-Giemsa) examples of mouse basophils exist in the literature. However, 4 recent studies in the past 2 years have used flow cytometry and a defined
James J, Lee, Michael P, McGarry
openaire   +3 more sources

Human cord blood derived immature basophils show dual characteristics, expressing both basophil and eosinophil associated proteins [PDF]

open access: yes, 2012
Basophils are blood cells of low abundance associated with allergy, inflammation and parasite infections. To study the transcriptome of mature circulating basophils cells were purified from buffy coats by density gradient centrifugations and two-step ...
Grundström Jeanette   +30 more
core   +2 more sources

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