Results 21 to 30 of about 108,915 (302)

Regulatory T cells do not suppress rather activate human basophils by IL-3 and STAT5-dependent mechanisms

OncoImmunology, 2020
Basophils play an important role in orienting Th2 immune response, and in the pathogenesis of allergic and inflammatory disorders. However, the mechanism by which basophils are kept in check remains unclear and hence we explored the role of regulatory T ...
Mrinmoy Das, Emmanuel Stephen-Victor, Jagadeesh Bayry   +2 more
doaj   +1 more source

Immediate-Type Hypersensitivity to Succinylated Corticosteroids [PDF]

, 2010
Background: Despite their frequent use, systemic corticosteroids have rarely elicited immediate-type reactions. Objective: We report two male patients, aged 26 and 70 years, respectively, with severe immediate-type hypersensitivity secondary to the ...
Raewer, Helen-Caroline, Helen-Caroline Räwer, Wolfgang Sieber, Sieber, Wolfgang, Walker, Annett Isabel, Annett Isabel Walker, Przybilla, Bernhard, Bernhard Przybilla   +7 more
core   +1 more source

Skin-homing basophils and beyond

Frontiers in Immunology, 2022
Basophils have been implicated in type 2 inflammation and numerous disorders in the skin such as helminth infection, atopic dermatitis, and urticaria.
Rintaro Shibuya, Rintaro Shibuya, Rintaro Shibuya, Brian S. Kim, Brian S. Kim, Brian S. Kim, Brian S. Kim   +6 more
doaj   +1 more source

Granulocytes: New Members of the Antigen-Presenting Cell Family

Frontiers in Immunology, 2017
Granulocytes, the most abundant types of leukocytes, are the first line of defense against pathogen invasion. However, the plasticity and diversity of granulocytes have been increasingly revealed, especially with regard to their versatile functions in ...
Ang Lin, Ang Lin, Karin Loré, Karin Loré   +3 more
doaj   +1 more source

Involvement of Hypoxia-Inducible Factor-1 in the Inflammatory Responses of Human LAD2 Mast Cells and Basophils [PDF]

, 2012
We recently showed that hypoxia-inducible factor 1 (HIF-1) plays a crucial role in the pro-allergic functions of human basophils by transcriptional control of energy metabolism via glycolysis as well as directly triggering expression of the angiogenic ...
Claire L Streatfield, Sumbayev, Vadim V., Yasinska, Inna M., Gibbs, Bernhard F., Streatfield, Claire L., Vadim V Sumbayev, Oniku, Abraham E., Bernhard F Gibbs, Streatfield Claire L., Yasinska Inna, Sumbayev Vadim V., Inna Yasinska, Oniku Abraham E., Gibbs Bernhard F., Abraham E Oniku   +14 more
core   +2 more sources

The Allergen-Specific IgE Concentration Is Important for Optimal Histamine Release From Passively Sensitized Basophils

Frontiers in Allergy, 2022
BackgroundThe basophil histamine release (HR) assay can be used for allergy diagnosis in addition to the conventional measurement of allergen-specific IgE (sIgE).
Peter Stoffersen, Per S. Skov, Lars K. Poulsen, Bettina M. Jensen   +3 more
doaj   +1 more source

Kinetics of basophil hyporesponsiveness during short-course peanut oral immunotherapy [PDF]

, 2022
BACKGROUND: Oral immunotherapy (OIT) leads to suppression of mast cell and basophil degranulation along with changes in the adaptive immune response. OBJECTIVES: This study aimed to determine how rapidly these effects occur during OIT and more broadly ...
Keet, Corinne, Herlihy, Lauren, Li, Quefeng, Burks, A Wesley, Ye, Ping, Smeekens, Johanna M, Shreffler, Wayne, Yue, Xiaohong, Orgel, Kelly A, Kim, Edwin H, Burk, Caitlin, Hamilton, Deanna, Vickery, Brian P, Guo, Rishu, Kulis, Michael D   +14 more
core   +1 more source

カンジダ特異的IgG(4)抗体と気管支喘息 [PDF]

, 1991
Serum levels of Candida-specific IgG(4) antibodies were examined in 66 patients with bronchial asthma, relating to patient age and asthma severity. 1.
Tanizaki, Yoshiro, Okazaki, Morihiro, Harada, Hideo, Kitani, Hikaru, Takatori, Akimasa, Okuda, Hiroyuki, Mitsunobu, Fumihiro, Mifune, Takashi   +7 more
core   +1 more source

Changes in passively‐sensitized basophil activation to αS1‐casein after oral immunotherapy

Immunity, Inflammation and Disease, 2020
Introduction Immune response to cow's milk allergen (CMA) has been analyzed mostly using crude milk antigen or a mixture of various caseins. This study aimed to assess the changes in the immunological response against αS1‐casein during oral immunotherapy
Teruaki Matsui, Michihiro Naito, Kazunori Tagami, Iwao Tajima, Miyuki Teshigawara, Atsushi Makino, Katsumasa Kitamura, Yoshihiro Takasato, Shiro Sugiura, Chikako Yamada, Hidehiko Izumi, Ikuya Tsuge, Yasuto Kondo, Komei Ito   +13 more
doaj   +1 more source

Possible Association of Interleukin-31/-31RA Signalling and Basophils with Itch in Porokeratosis

Acta Dermato-Venereologica, 2023
is missing (Short communication)
Satoshi Okuno, Takashi Hashimoto, Riichiro Sugiura, Takahiro Satoh   +3 more
doaj   +1 more source