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1. The basophilic granule of blood and marrow cells does not show the brown color reaction with benzidine solutions that is characteristic of the neutrophilic and eosinophilic granules. It differs from these types also in other important microchemical and physical particulars. 2.
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Interactions between Innate Lymphoid Cells and Cells of the Innate and Adaptive Immune System
Type 2 innate lymphoid cells (ILC2s) are a major source of cytokines, which are also produced by Th2 cells and several cell types of the innate immune system.
Cornelia Symowski, David Voehringer
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NADPH oxidase-independent formation of extracellular DNA traps by basophils [PDF]
Basophils are primarily associated with a proinflammatory and immunoregulatory role in allergic diseases and parasitic infections. Recent studies have shown that basophils can also bind various bacteria both in the presence and the absence of opsonizing ...
Simon, Hans-Uwe +10 more
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Skin-homing basophils and beyond
Basophils have been implicated in type 2 inflammation and numerous disorders in the skin such as helminth infection, atopic dermatitis, and urticaria.
Rintaro Shibuya +6 more
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Caffeine affects the biological responses of human hematopoietic cells of myeloid lineage via downregulation of the mTOR pathway and xanthine oxidase activity [PDF]
Correction of human myeloid cell function is crucial for the prevention of inflammatory and allergic reactions as well as leukaemia progression. Caffeine, a naturally occurring food component, is known to display anti-inflammatory effects which have ...
Sumbayev, Vadim V. +22 more
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MHC class II expression in human basophils: induction and lack of functional significance. [PDF]
The antigen-presenting abilities of basophils and their role in initiating a Th2 phenotype is a topic of current controversy. We aimed to determine whether human basophils can be induced to express MHC Class II and act as antigen presenting cells for T ...
Astrid L Voskamp +4 more
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Role of Basophils in a Broad Spectrum of Disorders
Basophils are the rarest granulocytes and have long been overlooked in immunological research due to their rarity and similarities with tissue-resident mast cells.
Kensuke Miyake +2 more
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For many, the word adventure conjures travel to distant lands or the exploration of endless outer space. I hope this afternoon to show you that adventure still exists no further away than your fingertips. This is a chronicle of the adventures we have had with a “cinderella” cell in a drop of blood.
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Basophils in Chronic Urticaria [PDF]
Blood basophils are reduced in chronic urticaria and respond less well to immunologic stimuli.
Grattan, C.E.H., C.E.H. Grattan
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Basophils from Cancer Patients Respond to Immune Stimuli and Predict Clinical Outcome
Basophils are involved in manifestations of hypersensitivity, however, the current understanding of their propensity for activation and their prognostic value in cancer patients remains unclear.
Heather J. Bax +19 more
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