Results 61 to 70 of about 56,684 (297)
Haematologica, 2009 Background The JAK2V617F mutation has been associated with constitutive and enhanced activation of neutrophils, while no information is available concerning other leukocyte subtypes.Design and Methods We evaluated correlations between JAK2V617F mutation ...
Lisa Pieri +7 more
doaj +1 more source
Basophils and Systemic Lupus Erythematosus in Murine Models and Human Patients
Biology, 2020 Basophils are the rarest cell population in the blood. Even though basophils are known to participate in some allergic reactions and immune responses to parasitic infections, their immunological role is still largely elusive.
Kuanysh Dossybayeva +2 more
doaj +1 more source
Identification of CD203c as a New Basophil-Specific Flow-Marker in Ph+ Chronic Myeloid Leukemia
Cells, 2022 Basophilia is a crucial prognostic variable in Ph-chromosome-positive chronic myeloid leukemia (CML). The ectoenzyme CD203c is an activation-linked surface antigen that is expressed specifically on basophil-committed progenitor cells and mature basophils.
Irina Sadovnik +11 more
doaj +1 more source
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda +4 more
wiley +1 more source
Elevated, FcεRI‐dependent MRGPRX2 expression on basophils in chronic urticaria
Skin Health and Disease, 2023 Background Chronic urticaria (CU) is a skin condition driven by mast cells and basophils. The exact responsiveness profile of these cells, especially regarding the anti‐IgE treatment, Omalizumab, is not fully investigated.
Ewa A. Bartko +4 more
doaj +1 more source
Basophils in Tumor Microenvironment and Surroundings
, 2020 Basophils represent approximately 1% of human peripheral blood leukocytes. Their effector functions were initially appreciated in the 1970s when basophils were shown to express the high-affinity receptor (FcεRI) for IgE and to release proinflammatory ...
Varricchi, Gilda +5 more
core +1 more source
BH3 mimetics efficiently induce apoptosis in mouse basophils and mast cells. [PDF]
, 2017 Basophil granulocytes and mast cells are recognized for their roles in immunity and are central effectors of diverse immunological disorders. Despite their similarities, there is emerging evidence for non-redundant roles of the circulating yet scarce ...
Reinhart, Ramona +9 more
core +2 more sources
Animal Research and One Health, EarlyView.Intensive or organic farming systems may expose pigs to management or environmental challenges. Our preliminary results concluded that organic farming might enhance adaptive immune function, showing that improvements in welfare can translate into measurable immunological benefits, based on the correlation between welfare assessment and physiological ...
Dorotea Ippolito +15 more
wiley +1 more source
Basophils in pruritic skin diseases
Frontiers in Immunology, 2023 Basophils are rare cells in the peripheral blood which have the capability to infiltrate into the skin. Invasion of basophils has been detected in pruritic skin diseases, including atopic dermatitis, bullous pemphigoid, chronic spontaneous urticaria and ...
Daniela Wiebe +6 more
doaj +1 more source
Basophils promote innate lymphoid cell responses in inflamed skin. [PDF]
, 2014 Type 2 inflammation underlies allergic diseases such as atopic dermatitis, which is characterized by the accumulation of basophils and group 2 innate lymphoid cells (ILC2s) in inflamed skin lesions.
Wang, Kelvin +10 more
core +1 more source