Results 161 to 170 of about 17,078 (200)

Traveling-wave chemotaxis of neutrophil-like HL-60 cells. [PDF]

Mol Biol Cell
Ishida M, Uwamichi M, Nakajima A, Sawai S.   +3 more
europepmc   +1 more source

Editorial: Exploring sulfur compounds' role in inflammation and therapeutic potential. [PDF]

Front Immunol
Iciek M, Sawa T, Lauriano ER, Kotańska M.   +3 more
europepmc   +1 more source

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Granulocyte response to oxidized FMLP

Inflammation, 1984
We prepared FMoxLP by oxidation of FMLP and evaluated its ability to trigger a variety of granulocyte responses. FMoxLP was found to depolarize granulocyte membranes; increase granulocyte oxygen consumption, superoxide production, and hydrogen peroxide production; compete with FMLP for binding to granulocytes; and stimulate granulocyte chemotaxis ...
K, Van Dyke, V, Castranova, C J, Van Dyke, J, Ma, K, Michaux, K W, Mollison, G W, Carter   +6 more
openaire   +2 more sources

Mitoxantrone Inhibits FMLP-Induced Degenerative Changes in Human Neutrophils

Molecular Biology, 2021
Neutrophils fight with invading pathogens through various mechanisms including degranulation, phagocytosis, and the release of neutrophil extracellular traps (NETs). This study aimed to determine the impact of a synthetic formyl-peptide (FMLP) on human neutrophils in vitro, and to determine the role of mitoxantrone (MTX), a pharmacological blocker of ...
S G, Ali, D, Shehwar, M R, Alam
openaire   +2 more sources

Pentoxifylline inhibits FMLP-induced macromolecular leakage

American Journal of Physiology-Heart and Circulatory Physiology, 1995
The acute inflammatory responses to the chemotactic peptide N-formyl-methionyl-leucyl-phenylalanine (FMLP) and the effects of pentoxifylline (PTXF) on the responses in vivo were studied. We used intravital microscopy with rat cremaster muscle preparation to determine inflammatory responses of microcirculation. Macromolecular leakage from postcapillary
K, Nakagawa, F N, Miller, A W, Knott, M J, Edwards   +3 more
openaire   +2 more sources

Mepacrine inhibits fMLP-induced activation of human neutrophil granulocytes, leukotriene B4 formation, and fMLP binding

Journal of Leukocyte Biology, 1992
Abstract Pulmonary sequestration and activation of polymorphonuclear leukocytes (PMNLs) are characteristic of many forms of acute lung injury. The present experiments were designed to study the effects of mepacrine on human neutrophils challenged with N-formylmethionyl- leucyl-phenylalanine (fMLP).
E, Földes-Filep, J G, Filep
openaire   +2 more sources

Studies on fMLP-receptor interaction and signal transduction pathway by means of fMLP-OMe selective analogues

Cellular Signalling, 2000
For-Thp-Leu-Ain-OMe ([Thp(1), Ain(3)] fMLP-OMe) (2), for-Met-delta(z)Leu-Phe-OMe ([delta(z)Leu(2)] fMLP-OMe) (3), for-Thp-Leu-Phe-OMe ([Thp(1)] fMLP-OMe) (4), and for-Met-Leu-Ain-OMe ([Ain(3)] fMLP-OMe) (5) are for-Met-Leu-Phe-OMe (fMLP-OMe) (1) analogues which discriminate between different responses of human neutrophils.
FABBRI, Elena, SPISANI, Susanna, BARBIN, Laura, BIONDI, Carla, BUZZI, Marco, TRANIELLO, Maria Serena, PAGANI ZECCHINI G, FERRETTI, Maria Enrica   +7 more
openaire   +2 more sources

Recovery of human basophils after FMLP‐stimulated secretion

Clinical & Experimental Allergy, 1996
SummaryBackgrottnd Basophils arc circulaling, secretory grunulocytes that are generally considered to be end‐stage cells. In one species of guinea‐pigs, basophilic leucocytes have been shown to recover from stimulated secretion in short‐term cultures.
A M, Dvorak, J A, Warner, P, Fox, L M, Lichtenstein, D W, Macglashan   +4 more
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Rebamipide Suppresses Formyl-methionyl-leucyl-phenylalanine (fMLP)-Induced Superoxide Production by Inhibiting fMLP-Receptor Binding in Human Neutrophils

The Journal of Pharmacology and Experimental Therapeutics, 2001
The purpose of the present work was to investigate the mechanism underlying the inhibitory action of rebamipide on superoxide anion (O2) production induced by the chemotactic peptide formyl-methionyl-leucyl-phenylalanine (fMLP) in human neutrophils.
C, Nagano, A, Azuma, H, Ishiyama, K, Sekiguchi, K, Imagawa, M, Kikuchi   +5 more
openaire   +2 more sources