Results 81 to 90 of about 17,078 (200)

Basophil Activation Test as Biomarker of Severity and Threshold of Allergic Reactions to Cow's Milk During Oral Food Challenges

Allergy, Volume 81, Issue 4, Page 1193-1204, April 2026.
The threshold of reactivity during fresh milk challenges was 70% lower than that of baked milk challenges, reflecting the higher allergenicity of fresh milk. BAT was the only biomarker statistically significantly different between severity and threshold groups, for baked milk and fresh milk allergies, respectively.
Holly Boyd, Irene Bartha, Ru‐Xin Foong, Marta Krawiec, Andreina Marques‐Mejias, Hannah F. Marshall, Suzana Radulovic, Faye Harrison, Grammatiki Antoneria, Zainab Jama, Matthew Kwok, Ewa Pietraszewicz, Malak Eghleilib, Cristian Ricci, Tom Marrs, Gideon Lack, George Du Toit, Alexandra F. Santos   +17 more
wiley   +1 more source

Punicic acid a conjugated linolenic acid inhibits TNFalpha-induced neutrophil hyperactivation and protects from experimental colon inflammation in rats. [PDF]

PLoS ONE, 2009
BACKGROUND:Neutrophils play a major role in inflammation by releasing large amounts of ROS produced by NADPH-oxidase and myeloperoxidase (MPO). The proinflammatory cytokine TNFalpha primes ROS production through phosphorylation of the NADPH-oxidase ...
Tarek Boussetta, Houssam Raad, Philippe Lettéron, Marie-Anne Gougerot-Pocidalo, Jean-Claude Marie, Fathi Driss, Jamel El-Benna   +6 more
doaj   +1 more source

Neutrophil‐reactive autoantibodies in blood donors: Can we expect TRALI?

Transfusion, Volume 66, Issue 4, Page 794-802, April 2026.
Abstract Background Transfusion‐related acute lung injury (TRALI) is a clinical condition characterized by acute non‐cardiogenic pulmonary edema during or after transfusion. Despite several mitigation strategies, TRALI remains a leading cause of transfusion‐related deaths.
Stefanie Jehle, Darvin Preuss, Yannick Waxmann, Anja Spies‐Naumann, Silke Schmidt, Rick Kapur, Ulrich J. Sachs, Behnaz Bayat   +7 more
wiley   +1 more source

Phosphoinositide Lipid Posphatase SHIP1 and PTEN Coordinate to Regulate Cell Migration and Adhesion [PDF]

, 2014
The second messenger phosphatidylinositol\((3,4,5)P_3 (PtdIns(3,4,5)P_3)\) is formed by stimulation of various receptors, including G protein–coupled receptors and integrins.
Bajrami, Besnik, Luo, Hongbo, Mondal, Subhanjan, Sakai, Jiro, Subramanian, Kulandayan K.   +4 more
core   +1 more source

ROS Activated NETosis of Bone Marrow CD55+ Intermediate Mature Neutrophils Through HIF1α‐PADI4 Pathway to Initiate Bone Aging

Advanced Science, Volume 13, Issue 16, 18 March 2026.
In this study, we find CD55+ neutrophils show activated NETosis within bone marrow, induce BMSC senescence and osteogenesis inhibition, finally leading to bone aging initiation. Mechanistically, ROS synergizes with the CD55‐driven HIF1α‐PADI4 pathway to promote NETosis.
Yutong Guo, Shengjie Cui, Xi Wen, Yidi Wang, Ben Wu, Yixiang Wang, Yan Gu   +6 more
wiley   +1 more source

Differences in Lectin‐Like Oxidized Low‐Density Lipoprotein Receptor‐1 Expression and Chemotaxis Between Neutrophils in the Oral Cavity and Those in Whole Blood

Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.
Polymorphonuclear neutrophils (PMNs) are crucial for oral health, yet their surface characteristics remain poorly understood. This study reveals elevated LOX‐1 expression on oral PMNs, indicating a heightened activation state, as evidenced by altered CD11b, CD66b, and CD62L levels.
Richard F. Kraus, Vanessa J. Stampfer, Konstantin J. Scholz, Michael A. Gruber, Fabian Cieplik   +4 more
wiley   +1 more source

Prompt inhibition of fMLP-induced Ca2+ mobilization by parenteral lipid emulsions in human neutrophils

Journal of Lipid Research, 2002
It remains unclear whether modulation of immune system functions by lipids contributes to the increased infection rate observed in patients treated with parenteral nutrition.
Geert Wanten, Angelique Rops, Sjenet E. van Emst-de Vries, Ton Naber, Peter H.G.M. Willems   +4 more
doaj   +1 more source

Ultraviolet light A irradiation induces immunosuppression associated with the generation of reactive oxygen species in human neutrophils [PDF]

Journal of Innovative Optical Health Sciences, 2016
Ultraviolet blood irradiation has been used as a physical therapy to treat many nonspecific diseases in clinics; however, the underlying mechanisms remain largely unclear.
Cunbo Li, Xuechen Shi, Mincai Chen, Guangxue Xu, Xinglei Su, Pengchong Jiang, Leiting Pan   +6 more
doaj   +1 more source

In vitro evaluation of the behaviour of human polymorphonuclear neutrophils in direct contact with chitosan-based membranes [PDF]

, 2007
Several novel biodegradable materials have been proposed for wound healing applications in the past few years. Taking into consideration the biocompatibility of chitosan-based biomaterials, and that they promote adequate cell adhesion, this work aims at
Castro, António G., Mano, J. F., Marques, A. P., Oliveira, Joaquim M., Reis, R. L., Santos, T. C., Silva, Simone Santos   +6 more
core   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, Volume 16, Issue 2, Page 268-278, February 2026.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source