Results 121 to 130 of about 22,945 (246)
A microRNA cluster in the Fragile-X region expressed during spermatogenesis targets FMR1. [PDF]
, 2019 Testis-expressed X-linked genes typically evolve rapidly. Here, we report on a testis-expressed X-linked microRNA (miRNA) cluster that despite rapid alterations in sequence has retained its position in the Fragile-X region of the X chromosome in ...
Cook-Andersen, Heidi +12 more
core
Reviewer #3 (Public Review): FMRP regulates neuronal migration via MAP1B
, 2023 Safia El Messaoudi +7 more
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Characterization of Fragile X mental retardation antibodies for use in cross-species immunoblotting, immunohistochemistry, and electron microscopy [PDF]
, 2009 This information is provided on Cogprints for colleagues in the Fragile X field who have requested it directly in the past. It is also a companion work to the article “Human Fragile X gene locus P1 artificial chromosome transgenic mice” from our group ...
Bauchwitz, Dr. Robert
core
Additional file 1 of FMRP attenuates activity dependent modifications in the mitochondrial proteome
, 2021 Pernille Bülow +4 more
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, 2014 Fragile X Syndrome (FXS) is a genetic disease due to a CGG trinucleotide expansion, named full mutation (greater than 200 CGG repeats), in the fragile X mental retardation 1 gene locus Xq27.3; which leads to an hypermethylated region in the gene promoter
Ayala-Zapata, Sebastián +5 more
core +1 more source
Frontiers in Aging Neuroscience, 2017 Fragile X mental retardation protein (FMRP) encoded by Fragile X mental retardation 1 (FMR1) gene is a RNA-binding regulator of mRNA translation, transport and stability with multiple targets responsible for proper synaptic function. Epigenetic silencing
Roman Smidak +12 more
doaj +1 more source
Frontiers in Neural Circuits, 2009 Fragile X syndrome, the most frequent form of familial mental retardation, is caused by mutation of the Fmr1 gene. Fmr1 encodes the Fragile X Mental Retardation Protein (FMRP), an mRNA binding protein regulating local, postsynaptic mRNA translation ...
Chanxia Li +3 more
doaj +1 more source
Implementação de um programa de mentoring para estudantes de graduação em saúde: a experiência da FMRP-USP [PDF]
, 2021 Gisele Curi de Barros +2 more
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eLife, 2019 Loss of the RNA binding protein FMRP causes Fragile X Syndrome (FXS), the most common cause of inherited intellectual disability, yet it is unknown how FMRP function varies across brain regions and cell types and how this contributes to disease ...
Kirsty Sawicka +8 more
doaj +1 more source
Pumping the brakes: A noncanonical RNA-binding domain in FMRP stalls elongating ribosomes [PDF]
, 2022 Sara K. Young
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