Results 111 to 120 of about 5,116 (221)

Curcumin relieves CUMS-induced depressive-like behaviors through PGC-1α/FNDC5/BDNF pathway [PDF]

open access: gold, 2021
Yanqin Wu   +6 more
openalex   +1 more source

Eight Weeks of High-Intensity Interval Static Strength Training Improves Skeletal Muscle Atrophy and Motor Function in Aged Rats via the PGC-1α/FNDC5/UCP1 Pathway

open access: yesClinical Interventions in Aging, 2021
Yijie Liu,1,2,* Chaoyang Guo,1,* Shuting Liu,1 Shuai Zhang,3 Yun Mao,4 Lei Fang1 1School of Rehabilitation Science, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, People’s Republic of China; 2Institute of Rehabilitation ...
Liu Y   +5 more
doaj  

Differential mitochondrial adaptation and FNDC5 production in brown and white adipose tissue in response to cold and obesity

open access: yesObesity
Fibronectin type III domain‐containing protein 5 (FNDC5) modulates adipocyte metabolism by increasing white and brown adipose tissue (WAT and BAT) browning and activity, respectively.
Gabriela Neira   +12 more
semanticscholar   +1 more source

Irisin Ameliorate Acute Pancreatitis and Acinar Cell Viability through Modulation of the Unfolded Protein Response (UPR) and PPARγ-PGC1α-FNDC5 Pathways

open access: yesBiomolecules
Acute pancreatitis (AP) entails pancreatic inflammation, tissue damage and dysregulated enzyme secretion, including pancreatic lipase (PL). The role of irisin, an anti-inflammatory and anti-apoptotic cytokine, in AP and exocrine pancreatic stress is ...
Avital Horwitz, Ruth Birk
semanticscholar   +1 more source

FNDC5/Irisin in dementia and cognitive impairment: update and novel perspective

open access: yesBrazilian Journal of Medical and Biological Research
Epidemiological surveys show that the incidence of age-related dementia and cognitive impairment is increasing and it has been a heavy burden for society, families, and healthcare systems, making the preservation of cognitive function in an increasingly aging population a major challenge. Exercise is beneficial for brain health, and FDNC5/irisin, a new
Xiaofeng Guo   +5 more
openaire   +3 more sources

Early Movement Restriction Affects FNDC5/Irisin and BDNF Levels in Rat Muscle and Brain

open access: yesInternational Journal of Molecular Sciences
Interaction with the environment appears necessary for the maturation of sensorimotor and cognitive functions in early life. In rats, a model of sensorimotor restriction (SMR) from postnatal day 1 (P1) to P28 has shown that low and atypical sensorimotor ...
Orlane Dupuis   +6 more
semanticscholar   +1 more source

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