Results 131 to 140 of about 6,156 (251)

The effects of resistance training, testosterone and palm (Phoenix dactylifera L.) pollen extract on the expression of FNDC5 and IGF1 genes in brown adipose tissue in male rats [PDF]

مجله علوم پزشکی فیض (پیوسته), 2023
Background and Aim: The use of testosterone enanthate is popular among athletes, especially resistance sports. Considering the side effects of using testosterone enanthate, it seems necessary to find alternative methods.
Ali Arbati, Hasan Matinhomaee, Mohammad Ali Azarbayjani, Saleh Rahmati   +3 more
doaj  

Greek goddess or Greek myth: the effects of exercise on irisin/FNDC5 in humans

The Journal of Physiology, 2013
While the fibronectin type 3-domain containing protein 5 (FNDC5) gene was first discovered over a decade ago (Ferrer-Martinez et al. 2002), new claims were recently attributed to the physiological function of FNDC5. In a paper published in Nature, Bostrom et al.
Philip J. Atherton, Bethan E. Phillips
openaire   +3 more sources

Irisin, Two Years Later [PDF]

, 2013
In January 2012, Boström and colleagues identified a new muscle tissue secreted peptide, which they named irisin, to highlight its role as a messenger that comes from skeletal muscle to other parts of the body.
CONTRERAS JIMENEZ, CRISTINA, Diéguez González, Carlos, Garrido Novelle, Marta, López Pérez, Miguel A., Romero Picó, Amparo   +4 more
core   +3 more sources

The Role of Exerkines in the Treatment of Knee Osteoarthritis: From Mechanisms to Exercise Strategies

Orthopaedic Surgery, Volume 17, Issue 4, Page 1021-1035, April 2025.
Exercise‐induced exerkines like interleukin‐6, insulin‐like growth factor‐1, and transforming growth factor‐β offer targeted benefits in knee osteoarthritis therapy, reducing inflammation, promoting cartilage repair, and relieving pain. This study highlights personalized exercise as a promising, noninvasive strategy to harness these molecular effects ...
Yuxiong Xu, Yizhuo Yang, Hanan Song, Ming Li, Weihao Shi, Tongwu Yu, Jianhao Lin, Yanli Yu   +7 more
wiley   +1 more source

Effects of physical activity on the link between PGC-1a and FNDC5 in muscle, circulating Ιrisin and UCP1 of white adipocytes in humans: A systematic review [PDF]

, 2017
Background:Exercise may activate a brown adipose-like phenotype in white adipose tissue. The aim of this systematic review was to identify the effects of physical activity on the link between peroxisome proliferator-activated receptor gamma coactivator 1-
Andreas D. Flouris, George S. Metsios, Ian M. Lahart, James A. Timmons, Per-Arne Svensson, Petros C. Dinas, Yiannis Koutedakis   +6 more
core   +1 more source

Driving research on successful aging and neuroprotection in Latin America: Insights from the inaugural symposium on brain resilience and healthy longevity

Alzheimer's &Dementia, Volume 21, Issue 3, March 2025.
Abstract INTRODUCTION Global life expectancy has steadily increased in recent decades, resulting in a significant rise in the number of individuals aged 80 years and older. This trend is also evident in Latin America, where life expectancy is improving, though at varying rates across countries and regions.
Yakeel T. Quiroz, David Aguillón, Joseph Arboleda‐Velasquez, Yamile Bocanegra, Gloria Patricia Cardona‐Gómez, Maria M. Corrada, Ibai Diez, Elkin Garcia‐Cifuentes, Kenneth Kosik, Lusiana Martinez, David Pineda‐Salazar, Rafael Posada, Norbel Roman, Diego Sepulveda‐Falla, Andrea Slachevsky, Marcio Soto‐Añari, Evelyn Tabilo, Daniel Vasquez, Andrés Villegas‐Lanau   +18 more
wiley   +1 more source

Feature Selection and Molecular Classification of Cancer Using Genetic Programming [PDF]

, 2007
Despite important advances in microarray-based molecular classification of tumors, its application in clinical settings remains formidable. This is in part due to the limitation of current analysis programs in discovering robust biomarkers and developing
Almal, Arpit A., Chinnaiyan, Arul M., Dhanasekaran, Saravana M., Ghosh, Debashis, Worzel, William P., Yu, Jianjun, Yu, Jindan   +6 more
core   +2 more sources

Irisin‐mediated muscle‐renal crosstalk as a protective mechanism against contrast‐induced acute kidney injury via cGAS‐STING signalling inhibition

Clinical and Translational Medicine, Volume 15, Issue 3, March 2025.
Irisin is identified as a crucial factor in muscle‒kidney crosstalk, inhibiting cGAS‐STING signaling and preventing dsDNA leakage via integrin αV/β5 in tubular epithelial cells (TECs), thus mitigating tubular injury and inflammation. ABSTRACT Background Contrast‐induced acute kidney injury (CI‐AKI) continues to pose a pressing clinical challenge during
Long Peng, Suhua Li, Qiang Huang, Yuxiang Sun, Juan Sun, Ting Luo, Yanlin Wang, Zhaoyong Hu, Weiyan Lai, Hui Peng   +9 more
wiley   +1 more source

Белая и бурая жировые ткани: взаимодействие со скелетной мышечной тканью [PDF]

, 2014
белая жировая тканьЖИРОВАЯ ТКАНЬЖИРОВАЯ ТКАНЬ БУРАЯСКЕЛЕТГИППОКАМПГОРМОНЫКАМБИАЛЬНЫЕ КЛЕТКИСТВОЛОВЫЕ КЛЕТКИМЫШЕЧНЫЕ ВОЛОКНАУМСТВЕННАЯ СПОСОБНОСТЬЧЕЛОВЕКА ...
Кичигина, Т. Н., Мяделец, В. О., Мяделец, О. Д., Соболевская, И. С.   +3 more
core  

Effect of Obesity and Exercise on the Expression of the Novel Myokines, Myonectin and Fibronectin Type III Domain Containing 5 [PDF]

, 2014
Metabolic dysfunction in skeletal muscle is a major contributor to the development of type 2 diabetes. Endurance exercise training has long been established as an effective means to directly restore skeletal muscle glucose and lipid uptake and metabolism.
Bond, Cherie E., Mart, Ryan, Peterson, Jonathan M.   +2 more
core   +3 more sources