Results 111 to 120 of about 7,212 (245)
Laser-scanning cytometry can quantify human adipocyte browning and proves effectiveness of irisin [PDF]
, 2015 Laser-scanning cytometry is presented as a tool allowing population scale analysis of ex vivo human brown adipogenic differentiation. It combines texture analysis and detection of Ucp1 protein content in single brown adipocytes of mixed cell populations ...
Bacso, Zsolt +5 more
core +1 more source
Advanced Science, Volume 13, Issue 11, 23 February 2026.Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang +18 more
wiley +1 more source
Irisina y envejecimiento [PDF]
, 2018 El envejecimiento es un proceso natural complejo que aborda un amplio espectro de cambios físicos y fisiológicos, y que puede conllevar la aparición dediferentes enfermedades relacionadas.
Carrasco Blanco, Alberto
core
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.ABSTRACT Background Irisin, an exercise‐induced myokine and adiponectin, an adipocyte‐derived hormone, are involved in energy metabolism and musculoskeletal health. However, their associations with obesity, abdominal obesity, sarcopenia and sarcopenic obesity remain unclear, and longitudinal evidence is limited.
Yejin Kim +7 more
wiley +1 more source
Metabolic effects of FGF-21: thermoregulation and beyond [PDF]
, 2015 Fibroblast growth factor (FGF)-21, a member of the FGF family, is a novel hormone involved in the control of metabolism by modulating glucose homeostasis, insulin sensitivity, ketogenesis, and promoting adipose tissue “browning.” Recent studies ...
Celi, Francesco S. +3 more
core +3 more sources
Effect of exercise training on the FNDC5/BDNF pathway in spontaneously hypertensive rats
Physiological Reports, 2019 Increased sympathetic activity contributes to the development of cardiovascular diseases such as hypertension. Exercise training lowers sympathetic activity and is beneficial for the prevention and treatment of hypertension and associated cognitive ...
Tao Wang +5 more
doaj +1 more source
La expresión génica de FNDC5 en distintos tejidos, y los niveles circulantes de irisina, están modificados por la dieta y las condiciones hormonales [PDF]
, 2016 ResumenXunta de Galicia; EM2013/011Instituto de Salud Carlos III; PI13 ...
Cordido, Fernando +4 more
core
Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function [PDF]
, 2016 Peripheral processes that mediate beneficial effects of exercise on the brain remain sparsely explored. Here, we show that a muscle secretory factor, cathepsin B (CTSB) protein, is important for the cognitive and neurogenic benefits of running. Proteomic
Becke, A +11 more
core +1 more source
Increased FNDC5 is associated with insulin resistance in high fat-fed mice
Physiological Reports, 2017 FNDC5/irisin, has recently been identified as a novel protein that stimulates the "browning" of white adipose by inducing thermogenesis via increased uncoupling protein 1 (UCP1). We tested the hypothesis that high fat diet-induced prediabetic mice would exhibit increased FNDC5 and this effect would be attenuated by chronic exercise.
Guilford, Brianne L. +5 more
openaire +2 more sources
Effect of saffron aqueous extract during resistance training on the expression of fibronectin type III domain-containing protein 5 in the hippocampus of rats with type 2 diabetes [PDF]
Complementary Medicine Journal of Faculty of Nursing and MidwiferyIntroduction: It has been demonstrated that fibronectin type III domain-containing protein 5 (FNDC5) improves cognitive function by increasing neurotrophic factors. Furthermore, type 2 diabetes causes a decrease in cognitive function. The combined effect
Farzad Baratyan +2 more
doaj