Results 11 to 20 of about 191,617 (348)
Frontiers in Cardiovascular Medicine, 2022 Foam cells play a vital role in the initiation and development of atherosclerosis. This review aims to summarize the novel insights into the origins, consequences, and molecular mechanisms of foam cells in atherosclerotic plaques.
Yuzhou Gui +3 more
doaj +3 more sources
BBA Advances, 2021 Objective: Probucol is a cholesterol-lowering agent whose ability to prevent atherosclerosis is currently under study. Herein, we investigate the putative mechanism of probucol by observation of changes in cellular cholesterol efflux and lipid droplet ...
Anouar Hafiane, MSc, PhD +5 more
doaj +1 more source
Preliminary study on the role of miR-16 in progression of coronary atherosclerosis and possible molecular mechanism [PDF]
Zhenduanxue lilun yu shijian, 2021 Objective: To explore the role of microRNA (miRNA, miR) -16 in the development of coronary atheromatous plaques and to study possible mechanism involved in the process.
ZHA Qing, YU Chenxi, LIU Ya, YANG Ling, YE Jiawen, LIU Yan
doaj +1 more source
Materials & Design, 2023 In this study, two types of polymeric periodic hybrid (PPH) structures with hexagonal and re-entrant cells were proposed and manufactured by 3D printing using polylactic acid (PLA). PVC foam was adopted as filler material.
Ting Liu, Changhai Chen, Yuansheng Cheng
doaj +1 more source
Foam Cell Specific LXRα Ligand [PDF]
PLoS ONE, 2013 The liver X receptor α (LXRα) is a ligand-dependent nuclear receptor and the major regulator of reverse cholesterol transport in macrophages. This makes it an interesting target for mechanistic study and treatment of atherosclerosis.We optimized a promising stilbenoid structure (STX4) in order to reach nanomolar effective concentrations in LXRα ...
Feldmann, Radmila +8 more
openaire +5 more sources
Frontiers in Physiology, 2022 Cholesterol-overloaded cells or “foam cells” in the artery wall are the biochemical hallmark of atherosclerosis, and are responsible for much of the growth, inflammation and susceptibility to rupture of atherosclerotic lesions.
Pinhao Xiang +2 more
doaj +1 more source
Identification and quantification of cell gas evolution in rigid polyurethane foams by novel GCMS methodology [PDF]
, 2019 Producción CientíficaThis paper presents a new methodology based on gas chromatography-mass spectrometry (GCMS) in order to separate and quantify the gases presented inside the cells of rigid polyurethane (RPU) foams.
Galakhova, Anastasiia +5 more
core +2 more sources
Foam: A General purpose Monte Carlo Cellular Algorithm [PDF]
, 2002 A general-purpose, self-adapting Monte Carlo (MC) algorithm implemented in the program {\tt Foam} is described. The high efficiency of the MC, that is small maximum weight or variance of the MC weight is achieved by means of dividing the integration ...
de Doncker +5 more
core +3 more sources
TREM-1 is a positive regulator of TNF-α and IL-8 production in U937 foam cells
Biomolecules & Biomedicine, 2012 The purpose of our study was to investigate the expression levels of TREM-1 (triggering receptor expressed on myeloid cells-1) in U937 foam cells and determine whether TREM-1 regulates the production of tumor necrosis factor-alpha and interleukin-8 in ...
Yu-Shi Wang, Xiang-Jun Li, Wai-Ou Zhao
doaj +1 more source
Identification and validation of hub genes involved in foam cell formation and atherosclerosis development via bioinformatics [PDF]
PeerJ, 2023 Background Foam cells play crucial roles in all phases of atherosclerosis. However, until now, the specific mechanisms by which these foam cells contribute to atherosclerosis remain unclear.
Da Teng +9 more
doaj +2 more sources