Results 301 to 310 of about 1,259,124 (381)

Nanotopography Modulates Mechanotransduction of Stem Cells and Induces Differentiation through Focal Adhesion Kinase

, 2013
Benjamin Kim Kiat Teo, Sum Thai Wong, Choon Kiat Lim, Terrence Y. S. Kung, Chong Hao Yap, Yamini Ramagopal, Lewis H. Romer, Evelyn K. F. Yim   +7 more
openalex   +2 more sources

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

Advanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou, Kenny A. van Kampen, Pierpaolo Fucile, Carlos Mota, Lorenzo Moroni   +4 more
wiley   +1 more source

How Actin Polymerization and Myosin II Activity Regulate Focal Adhesion Dynamics in Motile Cells. [PDF]

Int J Mol Sci
Kovaleva A, Solomatina E, Tlegenova M, Saidova A, Vorobjev IA.   +4 more
europepmc   +1 more source

Tuning the Dielectric Properties of Individual Clay Nanosheets by Interlayer Composition: Toward Nano‐Electret Materials

Advanced Functional Materials, EarlyView.
The dielectric properties of clays are studied on the level of individual monolayers and functional double stacks. The material breakdown characteristics and charge storage performance are analyzed. For illustration, a defined charge pattern representing a cuneiform character is produced, written into a microscopic clay tile, referencing the origins of
Sebastian Gödrich, Paul Markus, Matthias Stöter, Bernhard Biersack, Rainer Schobert, Josef Breu, Georg Papastavrou   +6 more
wiley   +1 more source

M64HCl, a focal adhesion kinase activator, promotes intestinal mucosal healing in rats. [PDF]

BMC Gastroenterol
Liu G, Elsayed AAR, Kwantwi LB, Gallardo-Macias R, Gurvich VJ, Basson MD.   +5 more
europepmc   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

Advanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram, Majd Machour, Janette Zavin, Roy Meretzki, Reut Lev‐Ari, Shulamit Levenberg   +5 more
wiley   +1 more source

Focal Adhesion Kinase Drives Rho/ROCK and mTOR Signaling to Protect and Augment Aortic Dissections. [PDF]

JACC Basic Transl Sci
Zhou Z, Guan P, Sarkar R, Yu Y, Richard A, Weiss D, Kawamura Y, Zhang C, Li Y, Vaisar T, Martin DR, Buja LM, Li Z, Venkatachalam K, Shen YH, LeMaire SA, Humphrey JD, Milewicz DM.   +17 more
europepmc   +1 more source

Advanced Flame Retardant Strategies and Fire Performance Assessment for Safer Photovoltaics in Buildings: A Two‐Part Review

Advanced Functional Materials, EarlyView.
The integration of photovoltaic (PV) systems into building structures introduces distinct fire risks with critical implications for occupant safety. This review examines the key fire hazards associated with PV implementation and explores mitigation strategies, including flame‐retardant additives.
Florian Ollagnon, Olaia Aurrekoetxea‐Arratibel, Emma Gottis, Heng‐Yu Li, Xabier Olano‐Azkune, Matthieu Despeisse, Antonin Faes, Christophe Ballif   +7 more
wiley   +1 more source

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

Activation of Focal Adhesion Pathway by <i>CIDEA</i> as Key Regulatory Axis in Lipid Deposition in Goat Intramuscular Precursor Adipocytes. [PDF]

Animals (Basel)
Shao P, Li Q, Liao Y, Wang Y, Lin Y, Xiang H, Du Z, Zhang C, Zhu J, Huang L.   +9 more
europepmc   +1 more source