Results 161 to 170 of about 51,195 (186)
Some of the next articles are maybe not open access.
Journal of Cellular Physiology, 1995
AbstractOur previous work demonstrated that 12(S)‐HETE, a lipoxygenase metabolite of arachidonic acid, promoted B16 amelanotic melanoma (B16a) cell spreading on fibronectin. In the current study, we investigated the biochemical mechanisms of the 12(S)‐HETE induced response.
D G, Tang +3 more
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AbstractOur previous work demonstrated that 12(S)‐HETE, a lipoxygenase metabolite of arachidonic acid, promoted B16 amelanotic melanoma (B16a) cell spreading on fibronectin. In the current study, we investigated the biochemical mechanisms of the 12(S)‐HETE induced response.
D G, Tang +3 more
openaire +2 more sources
Biochemical Journal, 2015
In blood platelets, stimulation of G protein-coupled receptors (GPCRs) by thrombin triggers the activation of Src family kinases (SFKs), resulting in the tyrosine-phosphorylation of multiple substrates, but the mechanism underlying this process is still poorly understood.
Canobbio, I. +9 more
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In blood platelets, stimulation of G protein-coupled receptors (GPCRs) by thrombin triggers the activation of Src family kinases (SFKs), resulting in the tyrosine-phosphorylation of multiple substrates, but the mechanism underlying this process is still poorly understood.
Canobbio, I. +9 more
openaire +3 more sources
Current Pharmaceutical Design, 2007
The formation of capillary-like structures during angiogenesis requires a series of well-orchestrated cellular events allowing endothelial cells and pericytes to migrate into the perivascular space. The proper activation of the migratory machinery in these cells is fine controlled by the presence of angiogenic challenges and by the interactions with ...
ANGELUCCI, ADRIANO, BOLOGNA, Mauro
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The formation of capillary-like structures during angiogenesis requires a series of well-orchestrated cellular events allowing endothelial cells and pericytes to migrate into the perivascular space. The proper activation of the migratory machinery in these cells is fine controlled by the presence of angiogenic challenges and by the interactions with ...
ANGELUCCI, ADRIANO, BOLOGNA, Mauro
openaire +3 more sources
Molecular Cancer Therapeutics, 2011
Abstract PTK2/FAK is a widely expressed non-receptor tyrosine kinase located mainly at focal adhesions. Sensing upstream signals from growth factor receptors as well as integrins, the enzyme contributes to activation of multiple downstream signaling pathways involved in the regulation of cell survival, proliferation and motility.
Ulrich A. Hirt +9 more
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Abstract PTK2/FAK is a widely expressed non-receptor tyrosine kinase located mainly at focal adhesions. Sensing upstream signals from growth factor receptors as well as integrins, the enzyme contributes to activation of multiple downstream signaling pathways involved in the regulation of cell survival, proliferation and motility.
Ulrich A. Hirt +9 more
openaire +1 more source
Der Pathologe, 2002
Expression analysis of the protein tyrosine kinases, focal adhesion kinase (FAK) and proline-rich tyrosine kinase2 (Pyk2) in high grade osteosarcomas.Expression of the kinases was evaluated qualitatively by immunohistochemical staining and quantitatively by real-time PCR.Osteoblastic cells of high grade osteosarcomas show a distinct FAK expression but ...
A, Schröder, G, Delling, E A, Kaiser
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Expression analysis of the protein tyrosine kinases, focal adhesion kinase (FAK) and proline-rich tyrosine kinase2 (Pyk2) in high grade osteosarcomas.Expression of the kinases was evaluated qualitatively by immunohistochemical staining and quantitatively by real-time PCR.Osteoblastic cells of high grade osteosarcomas show a distinct FAK expression but ...
A, Schröder, G, Delling, E A, Kaiser
openaire +1 more source
Progress on AlGaN-based solar-blind ultraviolet photodetectors and focal plane arrays
Light: Science and Applications, 2021Qing Cai, Haifan You, Hui Guo
exaly
Exploring the NK cell platform for cancer immunotherapy
Nature Reviews Clinical Oncology, 2020Jeffrey S Miller
exaly
Focal adhesion kinase: in command and control of cell motility
Nature Reviews Molecular Cell Biology, 2005David D Schlaepfer
exaly