Results 11 to 20 of about 50,276 (321)

An Assessment of the Pathological Classification and Postoperative Outcome of Focal Cortical Dysplasia by Simultaneous Hybrid PET/MRI

Brain Sciences, 2023
Objectives: The purpose of this research was to investigate whether MRI and Simultaneous Hybrid PET/MRI images were consistent in the histological classification of patients with focal cortical dysplasia. Additionally, this research aimed to evaluate the
Ning Wang, Lingjie Wang, Yixing Yu, Guangzheng Li, Changhao Cao, Rui Xu, Bin Jiang, Yongfeng Bi, Minjia Xie, Chunhong Hu, Wei Gao, Mo Zhu   +11 more
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Not Your Everyday FCD: Imaging Findings of Focal Cortical Dysplasia Type 1

Journal of the Belgian Society of Radiology, 2022
Teaching Point: The imaging findings of focal cortical dysplasia type 1 are less well-known than focal cortical dysplasia type 2 and consist of increased white matter signal intensity and blurring of the gray-white matter in a large region of the brain ...
Stijn Marcelis, Stephanie Vanden Bossche, Sven Dekeyzer   +2 more
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Limbic network co‐localization predicts pharmacoresistance in dysplasia‐related epilepsy

Annals of Clinical and Translational Neurology, 2023
To evaluate the role of focal cortical dysplasia co‐localization to cortical functional networks in the development of pharmacoresistance. One hundred thirty‐six focal cortical dysplasia patients with 3.0 T or 1.5 T MRI were identified from clinical ...
Nathan T. Cohen, Phat Chang, Taha Gholipour, Chima Oluigbo, L. Gilbert Vezina, Hua Xie, Anqing Zhang, William D. Gaillard   +7 more
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An integrated genetic analysis of epileptogenic brain malformed lesions

Acta Neuropathologica Communications, 2023
Focal cortical dysplasia is the most common malformation during cortical development, sometimes excised by epilepsy surgery and often caused by somatic variants of the mTOR pathway genes.
Atsushi Fujita, Mitsuhiro Kato, Hidenori Sugano, Yasushi Iimura, Hiroharu Suzuki, Jun Tohyama, Masafumi Fukuda, Yosuke Ito, Shimpei Baba, Tohru Okanishi, Hideo Enoki, Ayataka Fujimoto, Akiyo Yamamoto, Kentaro Kawamura, Shinsuke Kato, Ryoko Honda, Tomonori Ono, Hideaki Shiraishi, Kiyoshi Egawa, Kentaro Shirai, Shinji Yamamoto, Itaru Hayakawa, Hisashi Kawawaki, Ken Saida, Naomi Tsuchida, Yuri Uchiyama, Kohei Hamanaka, Satoko Miyatake, Takeshi Mizuguchi, Mitsuko Nakashima, Hirotomo Saitsu, Noriko Miyake, Akiyoshi Kakita, Naomichi Matsumoto   +33 more
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The ILAE consensus classification of focal cortical dysplasia: An update proposed by an ad hoc task force of the ILAE diagnostic methods commission

Epilepsia, 2022
Ongoing challenges in diagnosing focal cortical dysplasia (FCD) mandate continuous research and consensus agreement to improve disease definition and classification.
I. Najm, D. Lal, M. Alonso Vanegas, F. Cendes, Í. Lopes-Cendes, A. Palmini, E. Paglioli, H. Sarnat, C. Walsh, S. Wiebe, E. Aronica, S. Baulac, R. Coras, K. Kobow, J. Cross, R. Garbelli, H. Holthausen, K. Rössler, M. Thom, A. El-Osta, J. Lee, H. Miyata, R. Guerrini, Y. Piao, Dong Zhou, I. Blümcke   +25 more
semanticscholar   +1 more source

Multicenter Validation of a Deep Learning Detection Algorithm for Focal Cortical Dysplasia

Neurology, 2022
In the Research Article “Multicenter Validation of a Deep Learning Detection Algorithm for Focal Cortical Dysplasia” by Gill et al.,1 several links to the supplemental content were omitted in the final manuscript.

semanticscholar   +1 more source

Malformation of the Cortical Development Associated with Severe Clusters of Epileptic Seizures

Veterinary Sciences, 2022
Three cases of the malformation of the cortical development are described: a mixed breed dog and a Border Collie pup with a focal and diffuse cortical dysplasia, respectively, and a kitten with lissencephaly. All cases presented with intractable epilepsy
Aurora Cocchetto, Antonella Gallucci, Federica Biggio, Carlo Cantile   +3 more
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An open presurgery MRI dataset of people with epilepsy and focal cortical dysplasia type II

Scientific Data, 2023
Automated detection of lesions using artificial intelligence creates new standards in medical imaging. For people with epilepsy, automated detection of focal cortical dysplasias (FCDs) is widely used because subtle FCDs often escape conventional ...
Fabiane Schuch, Lennart Walger, Matthias H Schmitz, B. David, T. Bauer, A. Harms, Laura Fischbach, Freya Schulte, M. Schidlowski, Johannes T Reiter, Felix Bitzer, R. von Wrede, Atilla Rácz, Tobias Baumgartner, Valeri Borger, M. Schneider, Achim Flender, A. Becker, H. Vatter, B. Weber, Louisa Specht-Riemenschneider, A. Radbruch, R. Surges, T. Rüber   +23 more
semanticscholar   +1 more source

Detection of brain somatic mutations in focal cortical dysplasia during epilepsy presurgical workup

Brain Communications, 2023
Brain-restricted somatic variants in genes of the mechanistic target of rapamycin signalling pathway cause focal epilepsies associated with focal cortical dysplasia type II.
R. Checri, M. Chipaux, S. Ferrand-Sorbets, E. Raffo, C. Bulteau, S. Rosenberg, M. Doladilhe, G. Dorfmüller, H. Adle-Biassette, S. Baldassari, S. Baulac   +10 more
semanticscholar   +1 more source

mTOR pathway: Insights into an established pathway for brain mosaicism in epilepsy

Neurobiology of Disease, 2023
The mechanistic target of rapamycin (mTOR) signaling pathway is an essential regulator of numerous cellular activities such as metabolism, growth, proliferation, and survival.
Anna Gerasimenko, Sara Baldassari, Stéphanie Baulac   +2 more
doaj   +1 more source