Results 31 to 40 of about 713,420 (262)

Focal Myoclonus and Cortical Dysplasia

Pediatric Neurology Briefs, 1988
Four patients aged 9 to 19 years with focal myoclonus and intractable focal motor seizures beginning at age 4 to 6 years were treated surgically at the Montreal Neurological Hospital and Institute, McGill University, Montreal, Quebec, Canada.
J Gordon Millichap
doaj   +1 more source

Focal cortical dysplasia. Clinical-radiological-pathological associations

Neurología (English Edition), 2012
Introduction: The term focal cortical dysplasia (FCD) describes a particular migration disorder with a symptomatology mainly characterised by drug-resistant epileptic seizures, typical neuroradiological images, and histological characteristics, as well ...
I. Pascual-Castroviejo, J.L. Hernández-Moneo, M.L. Gutiérrez-Molina, J. Viaño, S.I. Pascual-Pascual, R. Velazquez-Fragua, C. Morales, D. Quiñones   +7 more
doaj   +1 more source

Simplified Classification of Focal Cortical Dysplasia

Pediatric Neurology Briefs, 2002
Sections of cortex from 52 of 224 (23%) patients with cortical dysplasia, operated on for drug-resistant partial epilepsy, were retrospectively re-examined histologically at Niguarda Hospital, and Istituto Nazionale Neurologico ‘C. Besta’, Milan, Italy.
J Gordon Millichap
doaj   +1 more source

Diffusion tensor imaging discriminates focal cortical dysplasia from normal brain parenchyma and differentiates between focal cortical dysplasia types

Insights into Imaging, 2023
Key points 1. DTI derived indices may be a useful tool for FCD characterisation. 2. FA and MD discriminated between FCD and contralateral brain parenchyma (CBP). 3. Status epilepticus increased the FA difference values between FCD and CBP. 4.
Antonio Giulio Gennari, Dorottya Cserpan, Ilona Stefanos-Yakoub, Raimund Kottke, Ruth O’Gorman Tuura, Georgia Ramantani   +5 more
doaj   +1 more source

Junctional instability in neuroepithelium and network hyperexcitability in a focal cortical dysplasia human model [PDF]

, 2021
Focal cortical dysplasia is a highly epileptogenic cortical malformation with few treatment options. Here, we generated human cortical organoids from patients with focal cortical dysplasia type II.
Delay, Lauriane, Araújo, Patricia AOR, Montenegro, Maria A, Almeida, Vanessa S, Cendes, Fernando, Adams, Jason W, Araújo, Patricia A O R, Avansini, Simoni H, Rogerio, Fabio, Puppo, Francesca, Tedeschi, Helder, Alvim, Marina K M, Coan, Ana C, França, Andréa FEC, Dias, Elayne V, Molina, Elsa, Rocha, Cristiane S, Yasuda, Clarissa L, Muotri, Alysson R, Alvim, Marina KM, França, Andréa F E C, Torres, Fabio R, Lopes Cendes, Iscia, Vieira, Andre S, Athié, Maria C, Martin, Mariana, Ghizoni, Enrico, Yaksh, Tony L, Elayne V Dias, Tony L Yaksh, Maria C Athié, Fabio R Torres, Simoni H Avansini, Vanessa S Almeida, Mariana Martin, Andre S Vieira, Patricia A O R Araújo, Jason W Adams, Ana C Coan, Helder Tedeschi, Cristiane S Rocha, Marina K M Alvim, Enrico Ghizoni, Fabio Rogerio, Clarissa L Yasuda, Andréa F E C França, Iscia Lopes Cendes, Maria A Montenegro, Alysson R Muotri, Francesca Puppo, Fernando Cendes, Lauriane Delay, Elsa Molina   +52 more
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Histological Subtypes of Focal Cortical Dysplasia

Pediatric Neurology Briefs, 2008
Clinical, EEG, MRI, neuropsychological, surgical, and seizure outcome data in 200 children with histologically proven cortical malformations were analyzed in a study at Motol University Hospital, Prague, Czech Republic, Miami Children's Hospital, and ...
J Gordon Millichap
doaj   +1 more source

Dual Pathology in Rasmussen’s Encephalitis: A Report of Coexistent Focal Cortical Dysplasia and Review of the Literature

Case Reports in Pathology, 2012
Rasmussen’s encephalitis is a well-established, albeit rare cause of medically intractable epilepsy. In a small number of Rasmussen's cases, a second pathology is identified, which independently can cause medically intractable seizures (dual pathology ...
Richard A. Prayson
doaj   +1 more source

Surgical Outcome in Focal Cortical Dysplasia

Pediatric Neurology Briefs, 2009
The predictors of surgical outcome and relevance of pathological severity were determined in 166 consecutive patients with intractable epilepsy and focal cortical dysplasias treated surgically at Konkuk University Medical Center, and National University ...
J Gordon Millichap
doaj   +1 more source

Neurologic phenotype of Schimke immuno-osseous dysplasia and neurodevelopmental expression of SMARCAL1

, 2008
Schimke immuno-osseous dysplasia (OMIM 242900) is an uncommon autosomal-recessive multisystem disease caused by mutations in SMARCAL1 (swi/snf-related, matrix-associated, actin-dependent regulator of chromatin, subfamily a-like 1), a gene encoding a ...
Hirano, R., Fujita, Y., Kanemura, Y., Deguchi, K., Sloan, E.A., Clewing, J.M., Lou, S., Choi, K., Powell, R., Northrop, J., Elizondo, L.I., Inoue, K., SantaCruz, K., Boerkoel, C.F., Huang, C., Willaime-Morawek, S., van der Kooy, D., Marwedel, K.M., Okano, H., Armstrong, D.L., Lucke, T.   +20 more
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Taylor’s focal cortical dysplasia revisited: History, original specimens and impact [PDF]

, 2021
50 years ago back in 1971, David C. Taylor and colleagues from England reported on a small series of surgical epilepsy cases proposing a new type of tissue lesion as a cause of difficult-to-treat focal epilepsy: a localized malformation of cerebral ...
Kasper, Burkhard S.
core   +1 more source