Results 21 to 30 of about 50,276 (321)
Epilepsia, 2023 Focal cortical dysplasias (FCDs) are malformations of cortical development and one of the most common pathologies causing pharmacoresistant focal epilepsy.
Lennart Walger +19 more
semanticscholar +1 more source
Problems of diagnosing focal cortical dysplasia
Эпилепсия и пароксизмальные состояния, 2021 Focal cortical dysplasia (FCD) is one of the most common causes in developing pharmacoresistant epilepsy. We present the clinical case of the patient with generalized seizures.
K. D. Yakovleva +2 more
doaj +1 more source
Multimodal mapping of regional brain vulnerability to focal cortical dysplasia.
Brain : a journal of neurology, 2023 Focal cortical dysplasia (FCD) type II is a highly epileptogenic developmental malformation and a common cause of surgically treated drug-resistant epilepsy. While clinical observations suggest frequent occurrence in the frontal lobe, mechanisms for such
H. Lee +23 more
semanticscholar +1 more source
The changing landscape in epilepsy imaging: Unmasking subtle and unique entities
Diagnostic and Interventional Radiology, 2022 Dramatic changes have occurred recently in the field of epilepsy, including a fundamental shift in the etiology of epileptogenic substrates found at surgery. Hippocampal sclerosis is no longer the most common etiology found at epilepsy surgery and this
Mehmet E. Adin +5 more
doaj +1 more source
Anti-seizure gene therapy for focal cortical dysplasia
bioRxiv, 2023 Focal Cortical Dysplasias (FCDs) are a common subtype of malformation of cortical development, which frequently present with a spectrum of cognitive and behavioural abnormalities as well as pharmacoresistant epilepsy.
Amanda Almacellas Barbanoj +12 more
semanticscholar +1 more source
Pediatric Neurology, 2013 Focal cortical dysplasias are among the most common causes of intractable epilepsy in children. As the neuropathology of these conditions has been better clarified, the nomenclature has undergone numerous revisions. Their recognition has grown with the use of neuroimaging, and recent advances in imaging technology will further improve detection ...
John N, Gaitanis, John, Donahue
openaire +3 more sources
Presurgical non-invasive diagnosis of focal cortical dysplasia
Эпилепсия и пароксизмальные состояния, 2019 In recent decades, MRI increased the success rate of the diagnosis and surgical treatment of epilepsy. Approximately 30% of patients with epilepsy suffer from the drug-resistant form of this disease.
S. V. Mirkhaydarov
doaj +1 more source
Focal Cortical Dysplasia in Pediatric Epilepsy [PDF]
Annals of Child Neurology, 2019 Focal cortical dysplasia (FCD) is the most common cause of intractable focal epilepsy in children undergoing epilepsy surgery. In these patients, seizures usually develop in early childhood and are often explosive from their onset. This review summarizes
Sun Ah Choi, Ki Joong Kim
doaj +1 more source
Focal cortical dysplasia: a practical guide for neurologists
Practical Neurology, 2023 Focal cortical dysplasia (FCD) is a malformation of cortical development characterised by disruption of cortical cytoarchitecture. Classification of FCDs subtypes has initially been based on correlation of the histopathology with relevant clinical ...
S. Balestrini +3 more
semanticscholar +1 more source
Sirolimus for epileptic seizures associated with focal cortical dysplasia type II
Annals of Clinical and Translational Neurology, 2022 To determine whether sirolimus, a mechanistic target of rapamycin (mTOR) inhibitor, reduces epileptic seizures associated with focal cortical dysplasia (FCD) type II.
Mitsuhiro Kato +11 more
semanticscholar +1 more source