Results 51 to 60 of about 506,213 (249)

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

The Impact of High-Energy Mining-Induced Tremor in a Fault Zone on Damage to Buildings

Energies, 2021
Seismic energy propagation from the hypocentre of mining-induced tremors usually causes an uneven distribution of the peak ground velocity PGVHmax in tectonically complicated structures, and consequently, an uneven distribution of damage to buildings ...
Elżbieta Pilecka, Krystyna Stec, Jacek Chodacki, Zenon Pilecki, Renata Szermer-Zaucha, Krzysztof Krawiec   +5 more
doaj   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

The MedSupport Multilevel Intervention to Enhance Support for Pediatric Medication Adherence: Development and Feasibility Testing

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard, Hital Patel, Paula C. Vincent, Justine Kahn, Kira Bona, Thai Hoa Tran, Elisa M. Rodriguez, Kristopher Attwood, Kara M. Kelly   +8 more
wiley   +1 more source

Focal Segmental Glomerulosclerosis: Genetics, Mechanism, and Therapies [PDF]

BioMed Research International, 2016
Focal segmental glomerulosclerosis (FSGS) is one of the primary glomerular disorders in both children and adults which can progress to end-stage renal failure. Recent advances in cell biology and genetics have found new molecules and signaling mechanisms in podocytes for the pathogenesis of FSGS. In addition, evidence-based approaches will guide to the
Andreas Kronbichler, Jun Oh, Björn Meijers, Jae Il Shin   +3 more
openaire   +4 more sources

Determination of focal mechanism solutions of the earthquakes with M≥4.0 occurred in the mainland of China during March to June 2024

地震科学进展
In this paper，the regional full waveform inversion using the broadband waveforms recorded by China Seismic Network were conducted，and the focal mechanism solutions of the 59 earthquakes with M≥4.0 occurred in the mainland of China during March to June ...
Shanshan Liang, Liye Zou, Yanqiong Liu, Xumao Li, Xiao Ren   +4 more
doaj   +1 more source

Focal Mechanism and Parameter of Volcano-Tectonic Earthquake Source, in Mount Guntur, West Java

Indonesian Journal on Geoscience, 2014
DOI: 10.17014/ijog.v6i1.111Guntur Volcano in West Java is one of the most active volcanoes in Indonesia. The last eruption took place in 1847 and the volcanic activity has been dormant since then, however its seismicity is active.
Sri Hidayati, Y. Suparman, A. Loeqman
doaj   +1 more source

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

Glucocorticoid receptor signalling activates YAP in breast cancer [PDF]

, 2017
The Hippo pathway is an oncosuppressor signalling cascade that plays a major role in the control of cell growth, tissue homoeostasis and organ size. Dysregulation of the Hippo pathway leads to aberrant activation of the transcription co-activator YAP ...
Bertolio, Rebecca, Bicciato, Silvio, Cappuzzello, Elisa, Del Sal, Giannino, Forcato, Mattia, Ingallina, Eleonora, Mano, Miguel, Marotta, Carolina, Neri, Carmelo, Rosato, Antonio, Ruggeri, Naomi, Sorrentino, Giovanni, Zannini, Alessandro   +12 more
core   +3 more sources

Focal depth determination of earthquakes with M≥2.5 in Jiaokou reservoir area in 2019 by multiple methods

地震科学进展, 2023
In this paper, the focal depth of earthquakes with magnitude 2.5 or above in Jiaokou reservoir area in 2019 was determined using the CAP method, the sPL depth phase method and the double difference positioning method.
Xiao Peng, Beilei Zhang
doaj   +1 more source