Results 71 to 80 of about 345,699 (263)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Dilatancy and the seismic focal mechanism [PDF]
In a recent paper F. C. Frank suggested that the seismic focal stress drop might by the consequence of a mechanical instability of deformation due to dilatancy of the crust and mantle. A more complete calculation shows that the instability attributed to dilatancy is a familiar general property of compacted granular masses independent of dilatancy.
openaire +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The accuracy of the focal mechanism solution can depend very significantly on the number of stations used, especially in the case of weak earthquakes and sparse networks.
D.V. Malytskyy +9 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Comparison of Crustal Stress and Strain Fields in the Himalaya–Tibet Region: Geodynamic Implications
The Himalaya–Tibet region represents a complex region of active deformation related to the ongoing India–Eurasia convergence process. To provide additional constraints on the active processes shaping this region, we used a comprehensive dataset of GNSS ...
Federico Pietrolungo +11 more
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The Intraplate Stress Field of West Africa
West Africa continues to host a growing number of low and intermediate‐magnitude earthquakes (M2‐5) along its passive margins, and its continental interior.
Jean‐Joel Legre +3 more
doaj +1 more source
Characteristics of focal mechanisms in Chile subduction
We use the Centroid Moment Tensor (CMT) solution of the earthquakes occurred in Chile subduction to analyze the characteristics of focal mechanisms. We define the angle between P, B, and T axes of focal mechanisms and three stress axes of tectonic stress
Wang Xiaoshan +3 more
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source

