Results 71 to 80 of about 1,404,808 (156)
NeurotherapeuticsThe clinical translation of Pterostilbene, a neuroactive stilbene with broad therapeutic potential, is hampered by its poor aqueous solubility and insufficient brain accumulation.
Xiaobo Yang +20 more
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, 2017 The alpha-folate receptor (alpha-FR) is highly-expressed in various non-mucinous tumors of epithelial origin, including ovarian carcinoma. The aim of this study was to investigate the relationship between alpha-folate receptor (alpha-FR) and the clinico ...
鄭文芳;陳祈安;江盈澄;謝長堯 +1 more
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Pharmacogenomics and Personalized Medicine, 2014 Loredana Serpe, Margherita Gallicchio, Roberto Canaparo, Franco DosioDepartment of Drug Science and Technology, University of Turin, ItalyAbstract: Among the gynecological malignancies, ovarian cancer is the leading cause of mortality in developed ...
Serpe L +3 more
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Frontiers in ImmunologyFolate receptors can perform folate transport, cell adhesion, and/or transcription factor functions. The beta isoform of the folate receptor (FRβ) has attracted considerable attention as a biomarker for immunosuppressive macrophages and myeloid-derived ...
Fenghua Zhang +16 more
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Biomolecules, 2019 In this study, we identified the proton-coupled folate transporter (PCFT) as a route for targeted delivery of drugs to some gliomas. Using the techniques of confocal imaging, quantitative reverse transcription-polymerase chain reaction (qRT-PCR), and ...
Yuriy V. Kucheryavykh +10 more
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, 2017 We investigated the effect of paternal folate status on folate content and expression of the folate transporter folate receptor α (FRα) in rat placental tissues.
장남수
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International Journal of Nanomedicine, 2008 Scott D Swanson1, Jolanta F Kukowska-Latallo2, Anil K Patri5, Chunyan Chen6, Song Ge4, Zhengyi Cao3, Alina Kotlyar3, Andrea T East7, James R Baker31Department of Radiology, The University of Michigan Medical School, 2Department of Internal Medicine, The ...
Scott D Swanson +5 more
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Specificity of the Interactions of Folate-Based Vectors with Folate Receptor-α
The study explores the molecular-level binding of a set of vector ligands─folate, methotrexate, raltitrexed, pemetrexed, 5-methyltetrahydrofolate, and pteroyl ornithine─to the membrane-embedded folate receptor-α, a relevant target in cancer therapy ...
Nikoleta Ivanova +6 more
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, 2014 Renal disease is the eighth leading cause of death in the United States. Early diagnosis is usually based on the detection of proteinuria or elevated serum creatinine, a relatively poor biomarker that does not accurately predict renal disease progression.
Elizabeth B. Somers +2 more
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Multimodal Bacteriochlorophyll Theranostic Agent
Theranostics, 2011 The complimentary ability of different noninvasive imaging technologies with therapeutic modalities can be used in tandem providing high-resolution and highly sensitive imaging of events at the molecular and cellular level providing a means for image ...
Tracy W.B. Liu, Juan Chen, Laura Burgess, Weiguo Cao, Jiyun Shi, Brian C. Wilson, Gang Zheng
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