Results 61 to 70 of about 1,404,808 (156)

Folate receptor-mediated intracellular delivery of recombinant caspase-3 for inducing apoptosis

, 2005
R ecombinant reversed caspase-3 (rev-caspase-3) is a pro-apoptotic gene capable of intracellular autocatalytic processing, which leads to programmed cell death.
Park, Tae Gwan, Kim, SW, Cho, Kyung Chul, Jeong, JH, Joe, Cheol O, Kim, Sung Wan, Jeong, Ji Hoon, Cho, KC, Chung, Hyun Jung   +8 more
core   +1 more source

Folate Receptor–Targeted Single-Photon Emission Computed Tomography/Computed Tomography to Detect Activated Macrophages in Atherosclerosis: Can It Distinguish Vulnerable from Stable Atherosclerotic Plaques?

Molecular Imaging, 2014
The need for noninvasive imaging to distinguish stable from vulnerable atherosclerotic plaques is evident. Activated macrophages play a role in atherosclerosis and express folate receptor folate receptor β (FR-β).
Leah C.J. Winkel, Harald C. Groen, Bibi S. van Thiel, Cristina Müller, Antonius F.W. van der Steen, Jolanda J. Wentzel, Marion de Jong, Kim Van der Heiden   +7 more
doaj   +1 more source

Comparison Study of Two Differently Clicked 18F-Folates—Lipophilicity Plays a Key Role

Pharmaceuticals, 2018
Within the last decade, several folate-based radiopharmaceuticals for Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET) have been evaluated; however, there is still a lack of suitable 18F-folates for clinical PET ...
Kathrin Kettenbach, Laura M. Reffert, Hanno Schieferstein, Stefanie Pektor, Raphael Eckert, Matthias Miederer, Frank Rösch, Tobias L. Ross   +7 more
doaj   +1 more source

Gluten-Free Products Are Insufficient Source of Folate and Vitamin B12 for Coeliac Patients [PDF]

, 2011
Bezglutenska prehrana, jedini lijek za oboljele od celijakije, može biti neuravnotežena zbog nedostataka nekih hranjivih tvari. Bezglutenski proizvodi sadrže manju količinu vitamina B, osobito folata, nego slični proizvodi koji sadrže gluten.
Panjkota Krbavčić, Ines, Colić Barić, Irena, Bituh, Martina, Zadro, Zvonko, Žižić, Vesna   +4 more
core  

Folate affects neural tube development through KDM6A [PDF]

Jichu yixue yu linchuang, 2020
Objective To investigate the effects of lysine-specific demethylase 6A (KDM6A) on neural tube defects (NTDs) in low folate environment. Methods Mouse embryonic stem cells (SV129), NTD mouse models and NTD human specimens were used.
GAO Jun, LI Jian-ting, XIE Qiu, ZHANG Yong-feng, QIAO Li-na, LIU Chang-yun, WANG Jian-hua
doaj  

Multifunctional folate receptor-targeting and pH-responsive nanocarriers loaded with methotrexate for treatment of rheumatoid arthritis

, 2017
Jinlong Zhao,1 Menghui Zhao,1 Changhui Yu,1 Xueyan Zhang,1 Jiaxin Liu,1 Xinwei Cheng,2 Robert J Lee,1,2 Fengying Sun,1 Lesheng Teng,1 Youxin Li1 1School of Life Sciences, Jilin University, Changchun, China; 2College of Pharmacy, Ohio State University ...
Zhao M, Liu J, Lee RJ, Li Y, Yu C, Zhang X, Sun F, Zhao J, Cheng X, Teng L   +9 more
core  

Synthesis and Preclinical Evaluation of Folate-NOTA-Al¹⁸F for PET Imaging of Folate-Receptor-Positive Tumors

, 2016
Folate-receptor-targeted PET radiotracers can potentially serve as versatile imaging agents for the diagnosis, staging, and prediction of response to therapy of patients with folate-receptor (FR)-expressing cancers.
Zhizhen Zeng (1948171), Dinko González Trotter (1929919), Patricia Miller (1948189), Philip S. Low (371711), Qingshou Chen (577262), Xiangjun Meng (384157), Daniel Rubins (2613742), Shu-An Lin (627149), Paul McQuade (1929925), Hyking Haley (2613739)   +9 more
core   +1 more source

Folates in berries [PDF]

, 2003
Folate concentrations in berries and berry products were investigated, determining folate retention from raw material to the final product. Folate content was quantified using a modified and systematically evaluated radioprotein-binding assay (RPBA). The
Strålsjö, Lena
core   +1 more source

Folate in autism neurodevelopment

Frontiers in Nutrition
Folate (vitamin B9) and vitamin B12 are essential micronutrients for cell growth, DNA synthesis, methylation, and one-carbon metabolism, with particular relevance to early development.
George Ayoub
doaj   +1 more source

Receptor-mediated gene delivery by folate-PEG-baculovirus in vitro

, 2007
Gene delivery using baculovirus is a promising approach for efficient and safe gene therapy compared with animal viruses. However, obstacles of baculovirus-mediated gene delivery include inactivation of baculovirus in human serum and whole blood and the ...
Yoo, Mi-Kyong, Cho, Chong-Su, Arote, Rohidas, Choi, Jae Young, Kim, You-Kyoung, Jiang, Hu-Lin, Cho, Myung-Haing, Je, Yeon Ho   +7 more
core   +1 more source