Results 61 to 70 of about 9,863 (285)

Pancytopénie sévère secondaire à un déficit en folates en dépit d’un dosage de folatesérythrocytaires normal

open access: yes, 2016
International audienceWe report the case of an alcoholic patient with severe pancytopenia with lowplasma folate level but normal erythrocyte folates and cobalamin levels.
Garnotel, Roselyne   +5 more
core   +1 more source

Sex‐ and Time‐Resolved Physiological and Gut Ecosystem Responses to a Food‐Grade Microbiome‐Targeted Intervention in Collegiate Endurance Athletes

open access: yesAdvanced Science, EarlyView.
In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang   +8 more
wiley   +1 more source

TROP2‐Targeting Chimeras (TRTACs) for Tumor Cell‐Selective Membrane Protein Degradation and Enhanced Drug Delivery

open access: yesAdvanced Science, EarlyView.
TROP2 is identified as a novel tumor‐selective lysosomal‐targeting receptor with established clinical relevance. TROP2‐targeting chimeras (TRTACs) are developed by genetically fusing a TROP2‐binding nanobody to nanobodies against specific target proteins.
Luping Chen   +10 more
wiley   +1 more source

Contraceptives with folate – new possibilities for prophylaxis of fetal congenital abnormalities

open access: yesГинекология, 2013
Neural tube defects (NTD) are a group of fetal congenital abnormalities which are formed in the first weeks of embryonal development. NTDs are formed when neural tube is not fully closed for the first 28 days after conception, i.e when a woman does not ...
V N Prilepskaya   +2 more
doaj  

Contraception and folates: new opportunities for prevention and treatment [PDF]

open access: yesГинекология, 2018
The article presents the latest information on new contraceptive drugs containing folic acid in the form of levomefolate calcium, which have not only contraceptive properties, but also have new capabilities for preparing for a future pregnancy and ...
V N Prilepskaia, E G Nazarenko
doaj   +1 more source

Context‐Dependent Inverse Association of Glucose–Lipid Metabolic Status With Anemia: Evidence From Multinational Multicohort Analyses

open access: yesAdvanced Science, EarlyView.
Across six multinational cohorts, higher triglyceride–glucose index values are consistently associated with lower prevalent and incident anemia, despite their established adverse cardiometabolic significance. This inverse relationship varies across inflammatory, cardiovascular, and renal contexts, suggesting that glucose–lipid metabolic status carries ...
Guosong Jiang   +13 more
wiley   +1 more source

On Folates in Yeasts -Exploring Yeasts as Vehicles for Biofortification of Folates in Food

open access: yes, 2008
High intake of the B vitamin folate during pregnancy is known to decrease the risk for development of neural tube defects. In addition, a good folate status may prevent the progression of several diseases such as megaloblastic anaemia, cardiovascular ...
Hjortmo, Sofia
core   +1 more source

The Intracellular Distribution of Folate Derivatives in Pea Leaves

open access: yesPteridines, 2003
After hydrolysis of polyglutamate derivatives, leaf extracts of pea (Pisum sativum L.) seedlings were examined for individual folates using high Performance liquid chromatography and microbiological assays employing Lactobacillus rhamnosus and ...
Chan Sherwin Y., Cossins Edwin A.
doaj   +1 more source

Folate contraception and clinical practice

open access: yesГинекология, 2020
Since the first pill, there has been a significant evolution of hormonal contraception: low- and micro-dose drugs have appeared, drugs with components as close as possible to endogenous hormones have been developed, new dosage regimens and routes of ...
Vera N. Prilepskaya   +1 more
doaj   +1 more source

Receptor‐Triggered Peptide Self‐Assembly Enables Multivalent Recruitment of Endogenous Antibodies for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Receptor‐triggered supramolecular self‐assembly converts monovalent antibody‐recruiting molecules into multivalent platforms directly on cancer cell membranes. The resulting fibrillar assemblies present clustered haptens that efficiently recruit endogenous antibodies, enabling selective complement‐mediated immune killing of EGFR‐positive cancer cells ...
Yihui Wang   +6 more
wiley   +1 more source

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