Results 81 to 90 of about 10,115,388 (315)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
AIP AdvancesFor meeting the requirements of tactical missiles seeking miniaturized launch devices for storage, transportation, and launch, a tube-launched missile wing is adopted, which folds before launch and quickly unfolds after launch.
Tiegang Lv +7 more
doaj +1 more source
Aerodynamic Analysis and Simulation for a Z-Shaped Folding Wing UAV
AerospaceThe potential of folding wing unmanned aerial vehicles (UAVs) in enhancing the adaptability of complex missions is substantial. Analyzing the aerodynamic characteristics of these UAVs is vital for optimizing the design of their folding wing configuration
Jin-Gang Wang, Xiang-Ying Guo
doaj +1 more source
Free energy landscape and multiple folding pathways of an H-type RNA pseudoknot. [PDF]
PLoS ONE, 2015 How RNA sequences fold to specific tertiary structures is one of the key problems for understanding their dynamics and functions. Here, we study the folding process of an H-type RNA pseudoknot by performing a large-scale all-atom MD simulation and bias ...
Yunqiang Bian +4 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Tissue-scale in vitro epithelial wrinkling and wrinkle-to-fold transition
Nature CommunicationsAlthough epithelial folding is commonly studied using in vivo animal models, such models exhibit critical limitations in terms of real-time observation and independent control of experimental parameters.
Jaeseung Youn +4 more
doaj +1 more source
Applied SciencesThe rapid deployment of folding wings is characterized by high-energy impacts, which require an immediate and effective response from the locking mechanism.
Guangqing Zhai +6 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Magnetic tweezers to capture the fast-folding λ6-85 in slow motion
Communications PhysicsForce spectroscopy gives access to the underlying free energy landscape of protein folding. Proteins exhibit folding rates between microseconds and hours.
César Augusto Quintana-Cataño +5 more
doaj +1 more source
Deep clustering of protein folding simulations
BMC Bioinformatics, 2018 Background We examine the problem of clustering biomolecular simulations using deep learning techniques. Since biomolecular simulation datasets are inherently high dimensional, it is often necessary to build low dimensional representations that can be ...
Debsindhu Bhowmik +3 more
doaj +1 more source