Results 41 to 50 of about 5,896 (149)

A Stable Isopterin Mimic of a Potent Bacterial Stimulant of T Cells

Chemistry – A European Journal, EarlyView.
A microbial metabolite covalently binds immunological protein MR1 to potently activate specific lymphocytes called MAIT cells, but it is too unstable for biological applications. Here, using synthesis, assays, protein crystallography, and computer modelling, we report a water‐stable analogue that activates reporter cells expressing the MAIT T cell ...
Jeffrey Y. W. Mak, Huy N. Hoang, Wael Awad, Xin Yi Lim, Damica D. Laurie, Ryan J. D. Rivero, James McCluskey, Alexandra J. Corbett, Jamie Rossjohn, David P. Fairlie   +9 more
wiley   +1 more source

N‐terminal pro‐brain natriuretic peptide and cardiorenal outcome in patients with anaemia in chronic kidney disease

ESC Heart Failure, Volume 12, Issue 2, Page 848-858, April 2025.
Abstract Aims Blood levels of N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) may be modified by low renal clearance and anaemia. The aim of this study was to investigate the impact of the blood NT‐proBNP level on cardiovascular and renal outcomes in patients with these two manifestations.
Hiroshi Nishi, Masaomi Nangaku, Tadashi Sofue, Tatsuo Kagimura, Ichiei Narita   +4 more
wiley   +1 more source

Diagnosis and management guidelines for infantile epileptic spasms syndrome around the world: A scoping review and comparative study of international approaches

Epilepsia, EarlyView.
Abstract Objective Infantile epileptic spasms syndrome (IESS) is an epileptic encephalopathy requiring rapid diagnosis and treatment to optimize neurodevelopmental outcomes. Although multiple national and regional guidelines exist, recommendations vary.
Gozde Erdemir, Chethan K. Rao, Anne Francine Pino, Christina Briscoe, Debopam Samanta, Jo M. Wilmshurst, Sonal Bhatia, Jessica L. Carpenter, Christina Hoei‐Hansen, Puneet Jain, Tommy Stodberg, Robyn Whitney, Ryuki Matsuura, Karina Rosso Astorga, Keryma Acevedo Gallinato, Pratibha Singhi, Aristides Hadijinicolaou, Gia Melikishvili, Patricia Smeyers, Nicola Specchio, Stéphane Auvin, Pediatric Epilepsy Research Consortium Infantile Spasm Work Group and International Committee   +21 more
wiley   +1 more source

Folic-acid Antagonists in Treatment of Psoriasis [PDF]

BMJ, 1965
A B, SHRANK, L M, BLENDIS
openaire   +2 more sources

PHENYLALANINE METABOLISM AND FOLIC ACID ANTAGONISTS* [PDF]

Journal of Clinical Investigation, 1961
T L, GOODFRIEND, S, KAUFMAN
openaire   +2 more sources

Synergistic antimicrobial activities of folic acid antagonists and nucleoside analogs. [PDF]

Antimicrob Agents Chemother, 2010
Zander J, Besier S, Ackermann H, Wichelhaus TA.   +3 more
europepmc   +1 more source

Folic-acid antagonists in psoriasis. [PDF]

BMJ, 1966
openaire   +3 more sources

Antagonism of Kinin Receptors B1 and B2 Attenuates Folic Acid-Induced Tubulointerstitial Fibrosis in Mice. [PDF]

Basic Clin Pharmacol Toxicol
Estrela GR, Budu A, Silva J, Brito R, Wasinski F, Barrera-Chimal J, Araujo RC.   +6 more
europepmc   +1 more source

The relationship between vitamin B9 (folate) supplementation and suicidality: a scoping review. [PDF]

Ment Health Clin
Noel C, Lombardi N, Price M, Herbert E, Lavigne JE.   +4 more
europepmc   +1 more source

Impact of RAAS blockers on serum potassium and mortality in a large dialysis cohort: a longitudinal analysis. [PDF]

Clin Kidney J
Calabrese V, Tripepi GL, Santoro D, Cernaro V, Mezzatesta S, Mattace-Raso F, Torino C.   +6 more
europepmc   +1 more source