Results 31 to 40 of about 12,926 (286)

Detection of Single Nucleotide Polymorphism Rs2013162 of IRF6 Gene in Patient with Cleft Lip and Palate [PDF]

, 2019
Background: Cleft lip and palate are congenital disorders which induce affected individuals medically, socially and psychologically. The objective of this study was to investigate the association of Single Nucleotide Polymorphism(SNP); rs2013162 of ...
Shehzad, H. (Husnain), Shehzad, O. (Osheen)   +1 more
core   +3 more sources

Evaluation of dihydrofolate reductase and dihydropteroate synthetase genotypes that confer resistance to sulphadoxine-pyrimethamine in Plasmodium falciparum in Haiti

Malaria Journal, 2012
Background Malaria caused by Plasmodium falciparum infects roughly 30,000 individuals in Haiti each year. Haiti has used chloroquine (CQ) as a first-line treatment for malaria for many years and as a result there are concerns that malaria parasites may ...
Carter Tamar E, Warner Megan, Mulligan Connie J, Existe Alexander, Victor Yves S, Memnon Gladys, Boncy Jacques, Oscar Roland, Fukuda Mark M, Okech Bernard A   +9 more
doaj   +1 more source

Polimorfismos en los genes de dihidrofolato-reductasa (dhfr) y dihidropteroato-sintasa (dhps) y modelado estructural del gen dhps en aislamientos colombianos de Toxoplasma gondii

Biomédica: revista del Instituto Nacional de Salud, 2014
Introducción. No existen reportes sobre las variaciones en la secuencia de los genes blanco de los medicamentos anti-Toxoplasma en aislamientos provenientes de Suramérica. Objetivo.
Liliana Jazmín Cortés, Sofía Duque, Myriam Consuelo López, Diego Moncada, Diego Molina, Jorge Enrique Gómez-Marín, María Luz Gunturiz   +6 more
doaj   +1 more source

Prescription and Other Medication Use in Pregnancy [PDF]

, 2018
OBJECTIVE: To characterize prescription and other medication use in a geographically and ethnically diverse cohort of women in their first pregnancy.
Caritis, Steve N., Chung, Judith, Dang, Danny T., Elovitz, Michal A., Esplin, M. Sean, Grobman, William A., Haas, David M., Hoffman, Matthew K., Iams, Jay D., Marsh, Derek J., Mercer, Brian M., Parker, Corette B., Parry, Samuel, Peaceman, Alan M., Reddy, Uma M., Saade, George R., Silver, Robert M., Simhan, Hyagriv N., Wapner, Ronald J., Wing, Deborah A.   +19 more
core   +1 more source

Dynamics of antifolate transport via the reduced folate carrier and the membrane folate receptor in murine leukaemia cells in vitro and in vivo [PDF]

, 2008
Murine L1210 leukaemia cells expressing either the reduced folate carrier (RFC) or the membrane folate receptor (MFR) were studied in vitro and in vivo to assess the dynamics of membrane transport of two categories antifolates; folate-based ...
Comijn, Elizabeth, Jansen, Gerrit, Kathmann, Ietje, Mauritz, Robert, Noordhuis, Paul, Peters, Godefridus, Pinedo, Herbert, Teshale, Habte   +7 more
core   +1 more source

What is the long term acid inhibitor treatment in gastroesophageal reflux disease? What are the potential problems related to long term acid inhibitor treatment in gastroesophageal reflux disease? How should these cases be followed?

The Turkish Journal of Gastroenterology, 2017
The meta-analyses of observational studies (OBS) showed the risk of any fracture and hip fracture slightly increased with proton pump inhibitor (PPI) treatment depending on the dose and regardless of time.
İbrahim Hatemi, Sinem Nihal Esatoğlu
doaj   +1 more source

Methotrexate – Genotoxic and teratogenic for medical staff of oncology wards?

Medycyna Pracy, 2015
Methotrexate (MTX) is one of the most widely used cytostatic drugs belonging to the folic acid antagonists. It is a substance non-classified as a carcinogen in the European Union and by the International Agency for Research on Cancer (IARC) as there is ...
Małgorzata Kupczewska-Dobecka
doaj   +1 more source

Distribution of Pharmacogenetic Polymorphisms and the Intervention Effects of Folic Acid Combined with Vitamin D in Community-based Patients with H-type Hypertension [PDF]

Zhongguo quanke yixue
Background H-type hypertension seriously affects people's health and quality of life. Currently, the clinical treatment of hypertension mainly selects drugs based on the experience, and the antihypertensive effect is not ideal.
PANG Aimei, GAO Wei, ZHANG Heng, PU Shuangshuang, GUO Lili, FAN Zirong, LIU Haixia, LIU Ruixia
doaj   +1 more source

Safety and benefits of interventions to increase folate status in malaria-endemic areas. [PDF]

, 2017
For decades, folic acid has routinely been given to prevent or treat anaemia in children, pregnant women and people with sickle cell disease. However, there is no conclusive evidence that folate deficiency anaemia constitutes a public health problem in ...
Adjalla, Allen, Antony, Baggott, Bailey, Beaudin, Benoist, Berry, Boele van Hensbroek, Calis, Carter, Charles, Choumenkovitch, Christianson, Chulay, Clark, Clarke, Crider, Daly, De Regil, Desai, Dhur, Dixit, Dzinjalamala, Eichholzer, Eijk, Ferone, Fishman, Fleming, Fleming, Fleming, Furness, Galloway, Geary, Gregson, Guyatt, Hubner, Kalmbach, Kamen, Kelly, Khanna, Koury, Krungkrai, Lassi, Lengeler, Levene, Lohner, Lucock, Luzzatto, Mahomed, Mbaye, Meremikwu, Metz, Metz, Miller, Mulenga, Nduati, Nzila, Nzila, Nzila, Nzila, Oniyangi, Ouma, Oyediran, Pegoraro, Piel, Pietrzik, Powers, Quinlivan, Relton, Rodriguez-Cortes, Rolschau, Sazawal, Schalhorn, Stern, Stokstad, Sweeney, Timmermans, Tong, Verhoef, Wald, Wang, Wang, WHO, WHO, WHO/FAO, Wilson, Yetley, Zhang   +88 more
core   +1 more source

Metformin and Micronutrient Status in Type 2 Diabetes: Does Polypharmacy Involving Acid-Suppressing Medications Affect Vitamin B12 Levels?

Diabetes, Metabolic Syndrome and Obesity, 2020
Michael Wakeman, David T Archer Faculty of Health and Wellbeing, Sciences Complex, University of Sunderland, Sunderland SR1, UKCorrespondence: Michael WakemanFaculty of Health and Wellbeing, Sciences Complex, University of Sunderland, Sunderland SR1 3SD,
Wakeman M, Archer DT
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